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UniProtKB - P94556 (MURI1_BACSU)
Protein
Glutamate racemase 1
Gene
racE
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Provides the (R)-glutamate required for cell wall biosynthesis.
UniRule annotationCatalytic activityi
- EC:5.1.1.3UniRule annotation
: peptidoglycan biosynthesis Pathwayi
This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationView all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 74 | Proton donor/acceptorUniRule annotationBy similarity | 1 | |
Active sitei | 185 | Proton donor/acceptorUniRule annotationBy similarity | 1 |
GO - Molecular functioni
- amino-acid racemase activity Source: GO_Central
- glutamate racemase activity Source: GO_Central
GO - Biological processi
- cell wall organization Source: UniProtKB-KW
- peptidoglycan biosynthetic process Source: GO_Central
- regulation of cell shape Source: UniProtKB-KW
Keywordsi
Molecular function | Isomerase |
Biological process | Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis |
Enzyme and pathway databases
BioCyci | BSUB:BSU28390-MONOMER |
BRENDAi | 5.1.1.1, 658 5.1.1.3, 658 |
UniPathwayi | UPA00219 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:racE Synonyms:glr, murI Ordered Locus Names:BSU28390 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000095453 | 1 – 272 | Glutamate racemase 1Add BLAST | 272 |
Proteomic databases
jPOSTi | P94556 |
PaxDbi | P94556 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P94556 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P94556 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 10 – 11 | Substrate bindingUniRule annotationCombined sources1 Publication | 2 | |
Regioni | 42 – 43 | Substrate bindingUniRule annotationCombined sources1 Publication | 2 | |
Regioni | 75 – 76 | Substrate bindingUniRule annotationCombined sources1 Publication | 2 | |
Regioni | 186 – 187 | Substrate bindingUniRule annotationCombined sources1 Publication | 2 |
Sequence similaritiesi
Belongs to the aspartate/glutamate racemases family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0796, Bacteria |
InParanoidi | P94556 |
OMAi | MPWGPRT |
PhylomeDBi | P94556 |
Family and domain databases
HAMAPi | MF_00258, Glu_racemase, 1 hit |
InterProi | View protein in InterPro IPR015942, Asp/Glu/hydantoin_racemase IPR001920, Asp/Glu_race IPR018187, Asp/Glu_racemase_AS_1 IPR033134, Asp/Glu_racemase_AS_2 IPR004391, Glu_race |
PANTHERi | PTHR21198:SF2, PTHR21198:SF2, 1 hit |
Pfami | View protein in Pfam PF01177, Asp_Glu_race, 1 hit |
SUPFAMi | SSF53681, SSF53681, 2 hits |
TIGRFAMsi | TIGR00067, glut_race, 1 hit |
PROSITEi | View protein in PROSITE PS00923, ASP_GLU_RACEMASE_1, 1 hit PS00924, ASP_GLU_RACEMASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P94556-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLEQPIGVID SGVGGLTVAK EIMRQLPKEN IIYVGDTKRC PYGPRPEEEV
60 70 80 90 100
LQYTWELTNY LLENHHIKML VIACNTATAI ALDDIQRSVG IPVVGVIQPG
110 120 130 140 150
ARAAIKVTDN QHIGVIGTEN TIKSNAYEEA LLALNPDLKV ENLACPLLVP
160 170 180 190 200
FVESGKFLDK TADEIVKTSL YPLKDTSIDS LILGCTHYPI LKEAIQRYMG
210 220 230 240 250
EHVNIISSGD ETAREVSTIL SYKGLLNQSP IAPDHQFLTT GARDQFAKIA
260 270
DDWFGHEVGH VECISLQEPI KR
Sequence cautioni
The sequence BAA28871 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 160 | K → Q in CAA99552 (PubMed:8969504).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z75208 Genomic DNA Translation: CAA99552.1 AL009126 Genomic DNA Translation: CAB14799.2 AB003685 Genomic DNA Translation: BAA28871.1 Different initiation. |
PIRi | B69688 |
RefSeqi | NP_390717.2, NC_000964.3 WP_010886589.1, NZ_JNCM01000036.1 |
Genome annotation databases
EnsemblBacteriai | CAB14799; CAB14799; BSU_28390 |
GeneIDi | 935934 |
KEGGi | bsu:BSU28390 |
PATRICi | fig|224308.43.peg.2969 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z75208 Genomic DNA Translation: CAA99552.1 AL009126 Genomic DNA Translation: CAB14799.2 AB003685 Genomic DNA Translation: BAA28871.1 Different initiation. |
PIRi | B69688 |
RefSeqi | NP_390717.2, NC_000964.3 WP_010886589.1, NZ_JNCM01000036.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1ZUW | X-ray | 1.75 | A/B/C | 1-272 | [»] | |
SMRi | P94556 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU28390 |
Proteomic databases
jPOSTi | P94556 |
PaxDbi | P94556 |
Genome annotation databases
EnsemblBacteriai | CAB14799; CAB14799; BSU_28390 |
GeneIDi | 935934 |
KEGGi | bsu:BSU28390 |
PATRICi | fig|224308.43.peg.2969 |
Phylogenomic databases
eggNOGi | COG0796, Bacteria |
InParanoidi | P94556 |
OMAi | MPWGPRT |
PhylomeDBi | P94556 |
Enzyme and pathway databases
UniPathwayi | UPA00219 |
BioCyci | BSUB:BSU28390-MONOMER |
BRENDAi | 5.1.1.1, 658 5.1.1.3, 658 |
Miscellaneous databases
EvolutionaryTracei | P94556 |
Family and domain databases
HAMAPi | MF_00258, Glu_racemase, 1 hit |
InterProi | View protein in InterPro IPR015942, Asp/Glu/hydantoin_racemase IPR001920, Asp/Glu_race IPR018187, Asp/Glu_racemase_AS_1 IPR033134, Asp/Glu_racemase_AS_2 IPR004391, Glu_race |
PANTHERi | PTHR21198:SF2, PTHR21198:SF2, 1 hit |
Pfami | View protein in Pfam PF01177, Asp_Glu_race, 1 hit |
SUPFAMi | SSF53681, SSF53681, 2 hits |
TIGRFAMsi | TIGR00067, glut_race, 1 hit |
PROSITEi | View protein in PROSITE PS00923, ASP_GLU_RACEMASE_1, 1 hit PS00924, ASP_GLU_RACEMASE_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MURI1_BACSU | |
Accessioni | P94556Primary (citable) accession number: P94556 Secondary accession number(s): O82826 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | July 7, 2009 | |
Last modified: | February 23, 2022 | |
This is version 147 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families