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Entry version 161 (17 Jun 2020)
Sequence version 2 (21 Feb 2001)
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Protein

Mitochondrial proton/calcium exchanger protein

Gene

Letm1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi700 – 7111PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi783 – 7942PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiport, Calcium transport, Ion transport, Transport
LigandCalcium, Metal-binding

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.97.1.3 the mitochondrial inner membrane k(+)/h(+) and ca(2+)/h(+) exchanger (letm1) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mitochondrial proton/calcium exchanger proteinCurated
Alternative name(s):
Leucine zipper-EF-hand-containing transmembrane protein 1
Short name:
dLetm11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Letm1
Synonyms:anon-60Da
ORF Names:CG4589
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0284252 Letm1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei237 – 257HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 60MitochondrionSequence analysisAdd BLAST60
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000007386161 – 1013Mitochondrial proton/calcium exchanger proteinAdd BLAST953

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P91927

PRoteomics IDEntifications database

More...
PRIDEi
P91927

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0019886 Expressed in adult hindgut (Drosophila) and 31 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P91927 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
63485, 5 interactors

Database of interacting proteins

More...
DIPi
DIP-23753N

Protein interaction database and analysis system

More...
IntActi
P91927, 7 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0072255

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P91927

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini280 – 554Letm1 RBDPROSITE-ProRule annotationAdd BLAST275
Domaini687 – 722EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini770 – 805EF-hand 2PROSITE-ProRule annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili104 – 131Sequence analysisAdd BLAST28
Coiled coili488 – 525Sequence analysisAdd BLAST38
Coiled coili573 – 653Sequence analysisAdd BLAST81
Coiled coili823 – 919Sequence analysisAdd BLAST97

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the LETM1 family.Curated

Keywords - Domaini

Coiled coil, Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1043 Eukaryota
ENOG410XRSP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183167

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008958_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P91927

KEGG Orthology (KO)

More...
KOi
K17800

Identification of Orthologs from Complete Genome Data

More...
OMAi
RVNKMIS

Database of Orthologous Groups

More...
OrthoDBi
516860at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P91927

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR011685 LETM1
IPR033122 LETM1_RBD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13202 EF-hand_5, 2 hits
PF07766 LETM1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00054 EFh, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473 SSF47473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS51758 LETM1_RBD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P91927-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNALLRHKGR NLRTSHLAQN VYKRFLKSNC CACSSVNVTD EPAKEDELPR
60 70 80 90 100
RSASTSVLEL SRSLGTYRRF QPHANYGYDY SGYGFRHLHT SRTLLETSSS
110 120 130 140 150
KIDATVKKLK NQQKEKVEEI MKEVANGQAA AVRASSAATA TASSEKGQNA
160 170 180 190 200
SATAGSTSAT ASTTSLAKTA DKSVAKPKKP LRTRIWDELV HYYHGFRLLF
210 220 230 240 250
IDVAICSKLL WRVLNGKTLT RRENKQLQRT TSDLFRLIPF SVFIIVPFME
260 270 280 290 300
LLLPLFIKFF PGMLPSTFQT STDRQEKLRQ SLSVRLEVAK FLQQTLDQMP
310 320 330 340 350
VQHKEHSSEE AKQFEAFFTK IRNPTEPVSN DEIIKFAKRF DDEITLDSLS
360 370 380 390 400
REQLAALCRV LELNTIGTTT LLRFQLRLKL RSLATDDRVI AREGVDSLDL
410 420 430 440 450
LELQQACKAR GMRAYGLTEE RLRFQLKEWI DLSLNEQVPP TLLLLSRTML
460 470 480 490 500
ISDDSITTDK LKETIRVLPD AVGAHTRHAI GESEGKVDNK TKIEIIKEEE
510 520 530 540 550
RKIREEREEE REETIAKRSA IKEEIPAPYV FAEKLSGSQD LLDHKEQSSV
560 570 580 590 600
SETDKGISST DVQLLSEALK TLSSDKQLVV EKETIKELKE ELADYKEDVE
610 620 630 640 650
ELREVRQVVK EPVRESRAAK LLYNRVNKMI SQLDNVLNDL EARQHQIKQA
660 670 680 690 700
ESSDYAASSP TVEPQQMVHI DELVATIRRM KEASDEERFK VVGDLLVKLD
710 720 730 740 750
ADKDGVISVN EITKAVQSID REATNIDKKQ LEEFTELLSK LASRRRHEEI
760 770 780 790 800
VHIDDLMNNI KVLKETSDEA RLKHIEAVLE KFDADKDGVV TVNDIRKVLE
810 820 830 840 850
SIGRDNIKLS DKAIEELISL LDKEQVLQAE QKIEKAIAKS MKEAEKLKSE
860 870 880 890 900
VDKADKDLSK LVNDIHDSAK EIQDIANEMR DKEETVPDKA KELKAEPAFK
910 920 930 940 950
DTAKTLKDNA KDLDDLAKDP KSDPKSPTKA STGSGPAGLS GGGPSSGSSG
960 970 980 990 1000
IATGSTTESA LREAAERQME KILPSTDIGL PPTIQTPSQP PTSKKATATA
1010
STLSTTITAK KLL
Length:1,013
Mass (Da):113,580
Last modified:February 21, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8C710380263F262E
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA71853 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti687E → Q in CAA71853 (PubMed:10071211).Curated1
Sequence conflicti690K → G in CAA71853 (PubMed:10071211).Curated1
Sequence conflicti717Q → H in CAA71853 (PubMed:10071211).Curated1
Sequence conflicti736E → D in CAA71853 (PubMed:10071211).Curated1
Sequence conflicti740K → R in CAA71853 (PubMed:10071211).Curated1
Sequence conflicti761K → E in CAA71853 (PubMed:10071211).Curated1
Sequence conflicti943G → S in CAA71853 (PubMed:10071211).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAM68316.1
AE013599 Genomic DNA Translation: AAM68317.1
AY047527 mRNA Translation: AAK77259.1
Y10912 mRNA Translation: CAA71853.1 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_611922.1, NM_138078.3
NP_726453.1, NM_166674.2
NP_726454.1, NM_166675.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0072347; FBpp0072254; FBgn0284252
FBtr0072348; FBpp0072255; FBgn0284252
FBtr0072349; FBpp0072256; FBgn0284252

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
37912

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG4589

UCSC genome browser

More...
UCSCi
CG4589-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAM68316.1
AE013599 Genomic DNA Translation: AAM68317.1
AY047527 mRNA Translation: AAK77259.1
Y10912 mRNA Translation: CAA71853.1 Frameshift.
RefSeqiNP_611922.1, NM_138078.3
NP_726453.1, NM_166674.2
NP_726454.1, NM_166675.2

3D structure databases

SMRiP91927
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi63485, 5 interactors
DIPiDIP-23753N
IntActiP91927, 7 interactors
STRINGi7227.FBpp0072255

Protein family/group databases

TCDBi2.A.97.1.3 the mitochondrial inner membrane k(+)/h(+) and ca(2+)/h(+) exchanger (letm1) family

Proteomic databases

PaxDbiP91927
PRIDEiP91927

Genome annotation databases

EnsemblMetazoaiFBtr0072347; FBpp0072254; FBgn0284252
FBtr0072348; FBpp0072255; FBgn0284252
FBtr0072349; FBpp0072256; FBgn0284252
GeneIDi37912
KEGGidme:Dmel_CG4589
UCSCiCG4589-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3954
FlyBaseiFBgn0284252 Letm1

Phylogenomic databases

eggNOGiKOG1043 Eukaryota
ENOG410XRSP LUCA
GeneTreeiENSGT00950000183167
HOGENOMiCLU_008958_1_0_1
InParanoidiP91927
KOiK17800
OMAiRVNKMIS
OrthoDBi516860at2759
PhylomeDBiP91927

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
37912

Protein Ontology

More...
PROi
PR:P91927

Gene expression databases

BgeeiFBgn0019886 Expressed in adult hindgut (Drosophila) and 31 other tissues
GenevisibleiP91927 DM

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR011685 LETM1
IPR033122 LETM1_RBD
PfamiView protein in Pfam
PF13202 EF-hand_5, 2 hits
PF07766 LETM1, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 2 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS51758 LETM1_RBD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLETM1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P91927
Secondary accession number(s): A4UZV1, Q0E8W7, Q9W160
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 21, 2001
Last modified: June 17, 2020
This is version 161 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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