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Entry version 127 (26 Feb 2020)
Sequence version 4 (01 Oct 2003)
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Protein
Submitted name:

SSD domain-containing protein

Gene

ptr-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • molting cycle, collagen and cuticulin-based cuticle Source: WormBase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SSD domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ptr-5Imported
ORF Names:C53C11.3Imported, CELE_C53C11.3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C53C11.3 ; CE34277 ; WBGene00004220 ; ptr-5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei72 – 89HelicalSequence analysisAdd BLAST18
Transmembranei326 – 346HelicalSequence analysisAdd BLAST21
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei390 – 412HelicalSequence analysisAdd BLAST23
Transmembranei432 – 454HelicalSequence analysisAdd BLAST23
Transmembranei461 – 486HelicalSequence analysisAdd BLAST26
Transmembranei526 – 547HelicalSequence analysisAdd BLAST22
Transmembranei754 – 770HelicalSequence analysisAdd BLAST17
Transmembranei776 – 797HelicalSequence analysisAdd BLAST22
Transmembranei804 – 825HelicalSequence analysisAdd BLAST22
Transmembranei859 – 879HelicalSequence analysisAdd BLAST21
Transmembranei886 – 914HelicalSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P91184

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P91184

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004220 Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini325 – 487SSDInterPro annotationAdd BLAST163

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 38DisorderedSequence analysisAdd BLAST38

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1934 Eukaryota
ENOG410XRZ4 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002359_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P91184

Identification of Orthologs from Complete Genome Data

More...
OMAi
VCAIFIP

Database of Orthologous Groups

More...
OrthoDBi
210960at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P91184

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003392 Ptc/Disp
IPR000731 SSD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02460 Patched, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50156 SSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P91184-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEDRVEQHD KQPMSDSDPL NTEKEHVLET EEPERAVSAM DNRQEKLNCL
60 70 80 90 100
HGFLSLRRMF YLVGYSVGRY PHAYLIVAFL ISINSLGMYR MVLKDRIRDG
110 120 130 140 150
YTPTNAPSRY ETDVLREFYN ISGDPAMTIM ILMPKNGTSM HAKANLDEAE
160 170 180 190 200
KLSKFFFNEF NASRDGRTLR FSQLCEPYCQ INKVFDLYKS AYDEQYKLFT
210 220 230 240 250
TERRISKSSN LSYPLATMSG FDIHLERSLF GVELNPKTEE NTTKLTTSDM
260 270 280 290 300
PPHRIITNMK HVEVIVFIFR GDRDSADKEK DLSRWELDAY EWSLNEHKSD
310 320 330 340 350
IVEVQIVGTD VLDNEMMKDG RRLTPFFAAG FGFEITFVSL CVILTAVYHN
360 370 380 390 400
CLDQGKLLIS LGAVLCPILA ITSTYGIVSI LGMRTNSFML VMPFLVMGIG
410 420 430 440 450
VDSCFLMIHS WQKERRAQAS GTGNRLGMVY ESVGPSITIT SLTDFLSFAI
460 470 480 490 500
GALAPTPETR LFCIASSIAL ALTYILQLVL FGPILAVATR YEHKTTTTSN
510 520 530 540 550
CNWRKWLKAC WKKCINVYCK ILSNKFFAVV VMLGTAIYWY FAIYGLMTMK
560 570 580 590 600
TRLDAVKILP KDSPLQRPNL VLTNLVWANY HPVTILINAP LDLENRHQMD
610 620 630 640 650
RYWNMVDEFE KMHNCKGKAS TLSWLRDYIK FSYHGEPFNL FAFFGLMTPE
660 670 680 690 700
VYEEVDPYQA NITTAKLPEF LKSPFFKHWD SFIHYHYEEG VIKLDRFMMN
710 720 730 740 750
VAYDNTSSWD TRIQLMTDWR KVANNYSDLN VTVWEPNGMF VDQMLSLGRT
760 770 780 790 800
ATQTGIWTLV CMAVVCAIFI PNPCSIITAT VSIASITTGV MGFLSLWSFD
810 820 830 840 850
LDPVVMAAVL MSIGLSVDFI AHVAYHFQLA HRKEIRNGKI KKIPLKGSTE
860 870 880 890 900
RLEHTLGAVA WPMIQAGVST ICCILPLLFR ASYSPSVFVA AIFLVVTFGM
910 920 930 940 950
LHGLLILPTF LAALPESVTT ANCYRVFLSS SSERSCRYVP RRDSTNSIEL
960
QKMERKDSLL N
Length:961
Mass (Da):109,465
Last modified:October 1, 2003 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCD89938649995232
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD67927.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T25657

NCBI Reference Sequences

More...
RefSeqi
NP_510810.3, NM_078409.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C53C11.3.1; C53C11.3.1; WBGene00004220

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181764

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C53C11.3

UCSC genome browser

More...
UCSCi
C53C11.3 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD67927.1
PIRiT25657
RefSeqiNP_510810.3, NM_078409.5

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

EPDiP91184
PaxDbiP91184

Genome annotation databases

EnsemblMetazoaiC53C11.3.1; C53C11.3.1; WBGene00004220
GeneIDi181764
KEGGicel:CELE_C53C11.3
UCSCiC53C11.3 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181764
WormBaseiC53C11.3 ; CE34277 ; WBGene00004220 ; ptr-5

Phylogenomic databases

eggNOGiKOG1934 Eukaryota
ENOG410XRZ4 LUCA
HOGENOMiCLU_002359_2_1_1
InParanoidiP91184
OMAiVCAIFIP
OrthoDBi210960at2759
PhylomeDBiP91184

Gene expression databases

BgeeiWBGene00004220 Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR003392 Ptc/Disp
IPR000731 SSD
PfamiView protein in Pfam
PF02460 Patched, 1 hit
PROSITEiView protein in PROSITE
PS50156 SSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP91184_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P91184
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: October 1, 2003
Last modified: February 26, 2020
This is version 127 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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