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Entry version 148 (07 Apr 2021)
Sequence version 2 (26 Apr 2004)
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Protein

Intermediate filament protein ifa-1

Gene

ifa-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cytoplasmic intermediate filaments make up the structural component of the cytoskeleton providing mechanical strength to cells. Essential protein required during embryogenesis especially for survival past the L1 larva stage, involved in intestine morphogenesis.2 Publications

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-4419969, Depolymerisation of the Nuclear Lamina

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Intermediate filament protein ifa-1
Alternative name(s):
Cel IF A1
Intermediate filament protein A1
Short name:
IF-A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ifa-1
ORF Names:F38B2.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
F38B2.1a ; CE31506 ; WBGene00002050 ; ifa-1
F38B2.1b ; CE31507 ; WBGene00002050 ; ifa-1
F38B2.1c ; CE05824 ; WBGene00002050 ; ifa-1
F38B2.1d ; CE24961 ; WBGene00002050 ; ifa-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Intermediate filament

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000638341 – 575Intermediate filament protein ifa-1Add BLAST575

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P90901

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P90901

PeptideAtlas

More...
PeptideAtlasi
P90901

PRoteomics IDEntifications database

More...
PRIDEi
P90901

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P90901

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform d is abundantly expressed in the marginal cells of the pharynx, forming apicobasally oriented thick filament bundles that are attached to the apical and basal plasma membrane by hemi-adherens junctions. Expression of isoform c is also seen in the excretory cells and in the uterus. Isoform c is detectable in the amphid sensory neurins and the pharyngeal-intestinal valve. Both isoform c and isoform d are expressed in the rectum and vulva and in some neurons of the tail. In larvae, expression is seen in the excretory cell, the vulva, the rectum and in the thick filament bundles of the pharynx. Expression in pharynx begins in late embryos.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00002050, Expressed in multi-cellular organism and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms some heteropolymeric filaments with ifb-1.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
46226, 22 interactors

Database of interacting proteins

More...
DIPi
DIP-25729N

Protein interaction database and analysis system

More...
IntActi
P90901, 10 interactors

Molecular INTeraction database

More...
MINTi
P90901

STRING: functional protein association networks

More...
STRINGi
6239.F38B2.1d

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P90901

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini69 – 422IF rodPROSITE-ProRule annotationAdd BLAST354
Domaini455 – 572LTDPROSITE-ProRule annotationAdd BLAST118

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 72HeadAdd BLAST72
Regioni73 – 104Coil 1AAdd BLAST32
Regioni105 – 118Linker 1Add BLAST14
Regioni119 – 256Coil 1BAdd BLAST138
Regioni257 – 274Linker 12Add BLAST18
Regioni275 – 422Coil 2Add BLAST148
Regioni423 – 572TailAdd BLAST150

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0977, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P90901

Identification of Orthologs from Complete Genome Data

More...
OMAi
THNIRNM

Database of Orthologous Groups

More...
OrthoDBi
701388at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P90901

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.5.1160, 2 hits
2.60.40.1260, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018039, IF_conserved
IPR039008, IF_rod_dom
IPR042180, IF_rod_dom_coil1B
IPR016451, Intermed_filament_ifa/ifb
IPR001322, Lamin_tail_dom
IPR036415, Lamin_tail_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00038, Filament, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF005546, Intermed_filamnt_Ifb-2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01391, Filament, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF74853, SSF74853, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00226, IF_ROD_1, 1 hit
PS51842, IF_ROD_2, 1 hit
PS51841, LTD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform a (identifier: P90901-1) [UniParc]FASTAAdd to basket
Also known as: a1-M

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMEITRETMS FTSTTPSARA PLGGRTTGNV TSQDRMLKIV TEMRSGAGSG
60 70 80 90 100
LSPFGQNAAS TIRDSREREK KEMSDLNDRL ASYIEKVRFL EAQNRKLAAD
110 120 130 140 150
LDALRSKWGK DTHNIRNMYE GELVDAQKLI DETNKQRKDM EGQLKKMQDE
160 170 180 190 200
LAEMRRKLED ATKGREQDRA KIDALLVTLS NLEAEISLLK RRIAQLEDEV
210 220 230 240 250
KRIKQENQRL LSELQRARTD LDQETLNRID YQNQVQTLLE EIDFLRRVHD
260 270 280 290 300
NEIKELQTLA SRDTTPENRE FFKNELSSAI RDIREEYDQV NNVHRNDMES
310 320 330 340 350
WYRLKVQEIQ TQSARQNMEQ GYAKEEVKRL RTQLSDLRGK LADLESRNSL
360 370 380 390 400
LEKQIQELNY QLEDDQRSYE AALNDRDSQI RKMREECQAL MVELQMLLDT
410 420 430 440 450
KQTLDAEIAI YRKMLEGEEN RAGLKQLVEQ VVKTHAITQE TDTETMRVVK
460 470 480 490 500
GETASRQSFQ RSAKGNVSIH EASPDGKFIV LQNTHRAKDE AIGEWKLKRR
510 520 530 540 550
IDGKRENVYT LPRDFVLRAG KTLKIFARNQ GVASPPDQLV YDAEDSFGSG
560 570
NNVQTILFNK EGEERATHIQ RQSTA
Length:575
Mass (Da):66,531
Last modified:April 26, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6B7C9679071B4A70
GO
Isoform b (identifier: P90901-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-8: MMEITRET → MYTTTRPA

Show »
Length:575
Mass (Da):66,461
Checksum:iF4BF0D4CCDF1A633
GO
Isoform c (identifier: P90901-3) [UniParc]FASTAAdd to basket
Also known as: a1-L, A1a

The sequence of this isoform differs from the canonical sequence as follows:
     1-8: Missing.

Show »
Length:567
Mass (Da):65,539
Checksum:iF204D5D0338534C9
GO
Isoform d (identifier: P90901-4) [UniParc]FASTAAdd to basket
Also known as: a1-H, A1b

The sequence of this isoform differs from the canonical sequence as follows:
     8-8: T → SEFLHFNYLNYSDDFPGA

Show »
Length:592
Mass (Da):68,548
Checksum:i3E2B474370CAC876
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A4V0IIR6A0A4V0IIR6_CAEEL
Intermediate filament protein ifa-1
ifa-1 CELE_F38B2.1, F38B2.1
604Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti124V → VV in CAA50182 (PubMed:8013462).Curated1
Sequence conflicti442 – 443Missing in CAA50182 (PubMed:8013462).Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0101441 – 8MMEITRET → MYTTTRPA in isoform b. Curated8
Alternative sequenceiVSP_0101451 – 8Missing in isoform c. Curated8
Alternative sequenceiVSP_0101468T → SEFLHFNYLNYSDDFPGA in isoform d. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X70834 Genomic DNA Translation: CAA50182.1
Z50045, Z73423 Genomic DNA Translation: CAA90365.3
Z50045, Z73423 Genomic DNA Translation: CAD44129.1
Z50045, Z73423 Genomic DNA Translation: CAL36494.1
Z50045, Z73423 Genomic DNA Translation: CBI83234.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T18872

NCBI Reference Sequences

More...
RefSeqi
NP_001076764.1, NM_001083295.2 [P90901-3]
NP_001257139.1, NM_001270210.1 [P90901-4]
NP_741902.1, NM_171777.5 [P90901-1]
NP_741903.1, NM_171778.3 [P90901-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F38B2.1a.1; F38B2.1a.1; WBGene00002050 [P90901-1]
F38B2.1b.1; F38B2.1b.1; WBGene00002050 [P90901-2]
F38B2.1c.1; F38B2.1c.1; WBGene00002050 [P90901-3]
F38B2.1c.2; F38B2.1c.2; WBGene00002050 [P90901-3]
F38B2.1c.3; F38B2.1c.3; WBGene00002050 [P90901-3]
F38B2.1d.1; F38B2.1d.1; WBGene00002050 [P90901-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181316

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F38B2.1

UCSC genome browser

More...
UCSCi
F38B2.1c.4, c. elegans

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X70834 Genomic DNA Translation: CAA50182.1
Z50045, Z73423 Genomic DNA Translation: CAA90365.3
Z50045, Z73423 Genomic DNA Translation: CAD44129.1
Z50045, Z73423 Genomic DNA Translation: CAL36494.1
Z50045, Z73423 Genomic DNA Translation: CBI83234.1
PIRiT18872
RefSeqiNP_001076764.1, NM_001083295.2 [P90901-3]
NP_001257139.1, NM_001270210.1 [P90901-4]
NP_741902.1, NM_171777.5 [P90901-1]
NP_741903.1, NM_171778.3 [P90901-2]

3D structure databases

SMRiP90901
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi46226, 22 interactors
DIPiDIP-25729N
IntActiP90901, 10 interactors
MINTiP90901
STRINGi6239.F38B2.1d

PTM databases

iPTMnetiP90901

Proteomic databases

EPDiP90901
PaxDbiP90901
PeptideAtlasiP90901
PRIDEiP90901

Genome annotation databases

EnsemblMetazoaiF38B2.1a.1; F38B2.1a.1; WBGene00002050 [P90901-1]
F38B2.1b.1; F38B2.1b.1; WBGene00002050 [P90901-2]
F38B2.1c.1; F38B2.1c.1; WBGene00002050 [P90901-3]
F38B2.1c.2; F38B2.1c.2; WBGene00002050 [P90901-3]
F38B2.1c.3; F38B2.1c.3; WBGene00002050 [P90901-3]
F38B2.1d.1; F38B2.1d.1; WBGene00002050 [P90901-4]
GeneIDi181316
KEGGicel:CELE_F38B2.1
UCSCiF38B2.1c.4, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181316
WormBaseiF38B2.1a ; CE31506 ; WBGene00002050 ; ifa-1
F38B2.1b ; CE31507 ; WBGene00002050 ; ifa-1
F38B2.1c ; CE05824 ; WBGene00002050 ; ifa-1
F38B2.1d ; CE24961 ; WBGene00002050 ; ifa-1

Phylogenomic databases

eggNOGiKOG0977, Eukaryota
InParanoidiP90901
OMAiTHNIRNM
OrthoDBi701388at2759
PhylomeDBiP90901

Enzyme and pathway databases

ReactomeiR-CEL-4419969, Depolymerisation of the Nuclear Lamina

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P90901

Gene expression databases

BgeeiWBGene00002050, Expressed in multi-cellular organism and 4 other tissues

Family and domain databases

Gene3Di1.20.5.1160, 2 hits
2.60.40.1260, 1 hit
InterProiView protein in InterPro
IPR018039, IF_conserved
IPR039008, IF_rod_dom
IPR042180, IF_rod_dom_coil1B
IPR016451, Intermed_filament_ifa/ifb
IPR001322, Lamin_tail_dom
IPR036415, Lamin_tail_dom_sf
PfamiView protein in Pfam
PF00038, Filament, 1 hit
PIRSFiPIRSF005546, Intermed_filamnt_Ifb-2, 1 hit
SMARTiView protein in SMART
SM01391, Filament, 1 hit
SUPFAMiSSF74853, SSF74853, 1 hit
PROSITEiView protein in PROSITE
PS00226, IF_ROD_1, 1 hit
PS51842, IF_ROD_2, 1 hit
PS51841, LTD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIFA1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P90901
Secondary accession number(s): G5ECT5
, Q0G822, Q17599, Q20141, Q8MLX8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 26, 2004
Last modified: April 7, 2021
This is version 148 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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