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UniProtKB - P90830 (P90830_CAEEL)
Protein
alpha-1,2-Mannosidase
Gene
CELE_F10C2.5
Organism
Caenorhabditis elegans
Status
Functioni
GO - Molecular functioni
- calcium ion binding Source: InterPro
- mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Source: InterPro
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- endoplasmic reticulum mannose trimming Source: InterPro
- mannose trimming involved in glycoprotein ERAD pathway Source: InterPro
Keywordsi
Molecular function | GlycosidaseUniRule annotation, Hydrolase |
Protein family/group databases
CAZyi | GH47, Glycoside Hydrolase Family 47 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:CELE_F10C2.5Imported, F10C2.5Imported |
Organismi | Caenorhabditis elegansImported |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | F10C2.5 ; CE09309 ; WBGene00008646 |
Subcellular locationi
Endoplasmic reticulum
Other locations
- membrane Source: InterPro
Keywords - Cellular componenti
Endoplasmic reticulumARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5004161766 | 19 – 781 | alpha-1,2-MannosidaseSequence analysisAdd BLAST | 763 |
Keywords - PTMi
GlycoproteinARBA annotationProteomic databases
EPDi | P90830 |
PaxDbi | P90830 |
PeptideAtlasi | P90830 |
Expressioni
Gene expression databases
Bgeei | WBGene00008646, Expressed in germ line (C elegans) and 5 other tissues |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 551 – 571 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 607 – 641 | Sequence analysisAdd BLAST | 35 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysis, SignalSequence analysisPhylogenomic databases
eggNOGi | KOG2429, Eukaryota |
GeneTreei | ENSGT00940000167182 |
HOGENOMi | CLU_003818_5_4_1 |
InParanoidi | P90830 |
OMAi | MVESLMY |
OrthoDBi | 434316at2759 |
PhylomeDBi | P90830 |
Family and domain databases
Gene3Di | 1.50.10.10, 1 hit |
InterProi | View protein in InterPro IPR012341, 6hp_glycosidase-like_sf IPR044674, EDEM1/2/3 IPR001382, Glyco_hydro_47 IPR036026, Seven-hairpin_glycosidases |
PANTHERi | PTHR45679, PTHR45679, 1 hit |
Pfami | View protein in Pfam PF01532, Glyco_hydro_47, 1 hit |
PRINTSi | PR00747, GLYHDRLASE47 |
SUPFAMi | SSF48225, SSF48225, 1 hit |
i Sequence
Sequence statusi: Complete.
P90830-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MITRKAIFFL ALASIIQASD DSEAPDNKKS SIRFTPSVID SYREKVQKMF
60 70 80 90 100
YHAYNGYLDH AFPLDELKPI TCVGQDTWGS FSLSLIDALD TLLVMGNTTE
110 120 130 140 150
FRRAVSLVLE KARDDANVNV SVFETNIRVV GGLISAHMLA GRHKDLVVDW
160 170 180 190 200
EGYPCDSPLL KLAVKMADRL MPAFNTETGM PYGTVNLKYG VHKDETPITC
210 220 230 240 250
TAGVGTFLIE FGTLSRLTGD DKYEKVALKA LDALWSTRSP IGLVGNHINV
260 270 280 290 300
QTGQWTATDS GIGAGVDSYF EYLAKGAYLF RRPSLMKQFH EHATSINKHV
310 320 330 340 350
RKGEWFMWVS MAKGSVSLPI FQSLEAFWPG TLTMVGDVQD ASRIMLTYSE
360 370 380 390 400
VIRKYGFPPE FYNIHNEEPG EKRAAFPLRP EMVESLMYLY RATKDETWLE
410 420 430 440 450
LGAEMIDAIE SSARTKCGYA TINNVKEHSI EDRMESFFLA ETTKYLYLLF
460 470 480 490 500
DPTNFIHSKG DQARILTSPK NLTCVIYGGG YIFNTEAHPV DPGMLDCCSV
510 520 530 540 550
QAKRDQEVGV KQVNNGDEHE KMNRTEKGGE KYFENQYGKN ENLIEFEVDE
560 570 580 590 600
KLKKESEKRK IELEAEKVKE NSHKAMLKVR EILVRAHQKD EAMQRNGETS
610 620 630 640 650
DSARKLMDQL YKAYPNHTAE LENLNKEAII EFEELQHLED IRELVREIPI
660 670 680 690 700
PEVFCEKCCV PLHEIVDSVV LRVLMADVYE YHFYPTRKTK FLHGPVCWLE
710 720 730 740 750
ETPRIEDDYK NEPPSVNTEK WNSPLFTSDQ ASLNDFIGDD LETVRKFGFK
760 770 780
TLLAPGYKKL DKLIAGQNIA LRRKKSWYYE V
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX284605 Genomic DNA Translation: CAB04078.1 |
PIRi | T20699 |
RefSeqi | NP_506018.1, NM_073617.3 |
Genome annotation databases
EnsemblMetazoai | F10C2.5.1; F10C2.5.1; WBGene00008646 |
GeneIDi | 179653 |
KEGGi | cel:CELE_F10C2.5 |
UCSCi | F10C2.5, c. elegans |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX284605 Genomic DNA Translation: CAB04078.1 |
PIRi | T20699 |
RefSeqi | NP_506018.1, NM_073617.3 |
3D structure databases
SMRi | P90830 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 6239.F10C2.5 |
Protein family/group databases
CAZyi | GH47, Glycoside Hydrolase Family 47 |
Proteomic databases
EPDi | P90830 |
PaxDbi | P90830 |
PeptideAtlasi | P90830 |
Genome annotation databases
EnsemblMetazoai | F10C2.5.1; F10C2.5.1; WBGene00008646 |
GeneIDi | 179653 |
KEGGi | cel:CELE_F10C2.5 |
UCSCi | F10C2.5, c. elegans |
Organism-specific databases
CTDi | 179653 |
WormBasei | F10C2.5 ; CE09309 ; WBGene00008646 |
Phylogenomic databases
eggNOGi | KOG2429, Eukaryota |
GeneTreei | ENSGT00940000167182 |
HOGENOMi | CLU_003818_5_4_1 |
InParanoidi | P90830 |
OMAi | MVESLMY |
OrthoDBi | 434316at2759 |
PhylomeDBi | P90830 |
Miscellaneous databases
PROi | PR:P90830 |
Gene expression databases
Bgeei | WBGene00008646, Expressed in germ line (C elegans) and 5 other tissues |
Family and domain databases
Gene3Di | 1.50.10.10, 1 hit |
InterProi | View protein in InterPro IPR012341, 6hp_glycosidase-like_sf IPR044674, EDEM1/2/3 IPR001382, Glyco_hydro_47 IPR036026, Seven-hairpin_glycosidases |
PANTHERi | PTHR45679, PTHR45679, 1 hit |
Pfami | View protein in Pfam PF01532, Glyco_hydro_47, 1 hit |
PRINTSi | PR00747, GLYHDRLASE47 |
SUPFAMi | SSF48225, SSF48225, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | P90830_CAEEL | |
Accessioni | P90830Primary (citable) accession number: P90830 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 1997 |
Last sequence update: | May 1, 1997 | |
Last modified: | January 19, 2022 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |