Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 77 (02 Jun 2021)
Sequence version 1 (01 May 1997)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Myosin-I binding protein Acan125

Gene
N/A
Organism
Acanthamoeba castellanii (Amoeba)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myosin-I binding protein Acan125Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcanthamoeba castellanii (Amoeba)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5755 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
AmoebaDB:ACA1_218370

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P90630

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P90630

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni860 – 935DisorderedSequence analysisAdd BLAST76
Regioni957 – 1121DisorderedSequence analysisAdd BLAST165

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi861 – 888Polar residuesSequence analysisAdd BLAST28
Compositional biasi895 – 915Polar residuesSequence analysisAdd BLAST21
Compositional biasi976 – 998Pro residuesSequence analysisAdd BLAST23
Compositional biasi1028 – 1079Basic and acidic residuesSequence analysisAdd BLAST52

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029766, CARMIL3
IPR001611, Leu-rich_rpt
IPR032675, LRR_dom_sf
IPR011993, PH-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24112:SF43, PTHR24112:SF43, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13516, LRR_6, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P90630-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSRSSSSGG GSTIMAKPVT EAEQQSVASI LGQRKDELQY VGWVAELVKK
60 70 80 90 100
KAEERVVVVG KWRIYFFSLV KGAAKLLRDA HLLELKEIKS TDSTTLVELV
110 120 130 140 150
FKTFSVPLGN CAADDLITAI RQSYEDVFFN LPPAIKCKLN VTPESRLRDV
160 170 180 190 200
EGPAQATLAK NCGGFSGTYQ ALCDFYGIPV RADICWDMDN LLPANHVKKF
210 220 230 240 250
NMKEFEQPVT PNELKALVDT LHFNNYFIGF VARDYRLDKD SMKVLTDMIG
260 270 280 290 300
VNTKMEELVL SRVEGTASAF EELGQAIAKN RNSALTSIDW SNNLIKDAGV
310 320 330 340 350
AALAAAVASM GHGLTSISLK GGDATKKGTV ALCTAFKKNV EMSRTLTVLN
360 370 380 390 400
LAGNRLDSDG TSALAAFVSG PNALQTLNIS GTAANLEMLL PAVMRGCTEL
410 420 430 440 450
EKFNISHNKV TAKTGPELKK FLQSCGRLSE LHMRDTAVPV QVVRDVIKAI
460 470 480 490 500
IGNNFITDFQ LDLAANKLGV LGANMLAGLA AEITTIKSLD LTDNDFGDEG
510 520 530 540 550
MSIIADGLCH NSSLRELHLG DNWTRNKTKA RSQAVDNLIE LISSECPLHK
560 570 580 590 600
LDLSCKVADN QIKTDILPFI YSLATNDTLK ELDISGNAMG DKVGIALGKA
610 620 630 640 650
FQINRTLSSL IWDRNGTRYA GFLGLKNGLE RNNVLVNMPV PVFDISDLLK
660 670 680 690 700
NEKPESALQV QQVVLHISEY IARNQSPKSK FAQGEDFSQH ISLMGTGAQE
710 720 730 740 750
EVQKLRQRIR AGQEEFTPGQ AAVLKDAEEN DNRIAAMQRI QDEVQQALAD
760 770 780 790 800
EVASKLGQFA SQLVPFLAST HDQLIDRVVD QVKEYKGFEK SAVEKLKMDL
810 820 830 840 850
KENAKTSLSK DAINKILAKS AASEITSEMT QGFVSSVSLT VDFVFDSLLD
860 870 880 890 900
KLDSIYYSQK GGAPTPRSQV ESADTRAESL PETSTADDTP SEASEEEPNL
910 920 930 940 950
GSESSDTSDL PTTTTDAAAA AEEAEPAVSV PARPTGVPMG GVALPFGAMR
960 970 980 990 1000
TGMPAMPMGG VVLRPTGSPL SQSATDRPKP VPPPRGAKPA PPPRTAKPLS
1010 1020 1030 1040 1050
FSQQPVLMPK PELLQPTTPT KPAAEPVTPV KKPEKEVKKN DTPAKKPEKD
1060 1070 1080 1090 1100
SKKPEKPAKS PKKPEKSLAK SKEPEPASAD MTELEAAESN LTHMTKDRPM
1110 1120
GPQRRRPQRK PQRRPMMSTA D
Length:1,121
Mass (Da):121,610
Last modified:May 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2C02AFB52B103698
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U89688 mRNA Translation: AAB57739.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T02764

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89688 mRNA Translation: AAB57739.1
PIRiT02764

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DRKX-ray1.42B977-986[»]
SMRiP90630
ModBaseiSearch...
PDBe-KBiSearch...

Organism-specific databases

VEuPathDBiAmoebaDB:ACA1_218370

Miscellaneous databases

EvolutionaryTraceiP90630

Family and domain databases

Gene3Di2.30.29.30, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR029766, CARMIL3
IPR001611, Leu-rich_rpt
IPR032675, LRR_dom_sf
IPR011993, PH-like_dom_sf
PANTHERiPTHR24112:SF43, PTHR24112:SF43, 1 hit
PfamiView protein in Pfam
PF13516, LRR_6, 3 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP90630_ACACA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P90630
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: June 2, 2021
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again