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UniProtKB - P88946 (P88946_HHV8)
Protein
Submitted name:
ORF K9
Gene
N/A
Organism
Human herpesvirus 8 type M
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- transcription cis-regulatory region binding Source: InterPro
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: UniProtKB
Names & Taxonomyi
Protein namesi | Submitted name: ORF K9Imported |
Organismi | Human herpesvirus 8 type MImported |
Taxonomic identifieri | 435895 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Peploviricota › Herviviricetes › Herpesvirales › Herpesviridae › Gammaherpesvirinae › Rhadinovirus › |
Interactioni
Binary interactionsi
P88946
With | #Exp. | IntAct |
---|---|---|
P88954 | 2 | EBI-936023,EBI-7923439 |
Q98141 | 2 | EBI-936023,EBI-7922007 |
Crebbp [P45481] from Mus musculus. | 6 | EBI-936023,EBI-296306 |
Protein-protein interaction databases
IntActi | P88946, 4 interactors |
MINTi | P88946 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 89 – 195 | IRF tryptophan pentad repeatInterPro annotationAdd BLAST | 107 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 60 | DisorderedSequence analysisAdd BLAST | 60 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 23 – 37 | Polar residuesSequence analysisAdd BLAST | 15 |
Family and domain databases
CDDi | cd00103, IRF, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 2.60.200.10, 1 hit |
InterProi | View protein in InterPro IPR001346, Interferon_reg_fact_DNA-bd_dom IPR019471, Interferon_reg_factor-3 IPR017855, SMAD-like_dom_sf IPR008984, SMAD_FHA_dom_sf IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR11949, PTHR11949, 2 hits |
Pfami | View protein in Pfam PF00605, IRF, 1 hit PF10401, IRF-3, 1 hit |
SMARTi | View protein in SMART SM00348, IRF, 1 hit SM01243, IRF-3, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF49879, SSF49879, 1 hit |
PROSITEi | View protein in PROSITE PS51507, IRF_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P88946-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDPGQRPNPF GAPGAIPKKP CLSQGSPGTS GSGAPCDEPS RSESPGEGPS
60 70 80 90 100
GTGGSAAAGD ITRQAVVAAI TEWSRTRQLR ISTGASEGKA SIKDWIVCQV
110 120 130 140 150
NSGKFPGVEW EDEERTRFRI PVTPLADPCF EWRRDGELGV VYIRERGNMP
160 170 180 190 200
VDASFKGTRG RRRMLAALRR TRGLQEIGKG ISQDGHHFLV FRVRKPEEEQ
210 220 230 240 250
CVECGVVAGA VHDFNNMARL LQEGFFSPGQ CLPGEIVTPV PSCTTAEGQE
260 270 280 290 300
AVIDWGRLFI RMYYNGEQVH ELLTTSQSGC RISSALRRDP AVHYCAVGSP
310 320 330 340 350
GQVWLPNVPN LACEIAKREL CDTLDACAKG ILLTSSCNGI FCVCYHNGPV
360 370 380 390 400
HFIGNTVPPD SGPLLLPQGK PTRIFNPNTF LVGLANSPLP APSHVTCPLV
410 420 430 440
KLWLGKPVAV GKLEPHAPSP RDFAARCSNF SDACVVLEIM PKPLWDAMQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U75698 Genomic DNA Translation: AAC57140.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U75698 Genomic DNA Translation: AAC57140.1 |
3D structure databases
SMRi | P88946 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | P88946, 4 interactors |
MINTi | P88946 |
Miscellaneous databases
PROi | PR:P88946 |
Family and domain databases
CDDi | cd00103, IRF, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 2.60.200.10, 1 hit |
InterProi | View protein in InterPro IPR001346, Interferon_reg_fact_DNA-bd_dom IPR019471, Interferon_reg_factor-3 IPR017855, SMAD-like_dom_sf IPR008984, SMAD_FHA_dom_sf IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR11949, PTHR11949, 2 hits |
Pfami | View protein in Pfam PF00605, IRF, 1 hit PF10401, IRF-3, 1 hit |
SMARTi | View protein in SMART SM00348, IRF, 1 hit SM01243, IRF-3, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF49879, SSF49879, 1 hit |
PROSITEi | View protein in PROSITE PS51507, IRF_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | P88946_HHV8 | |
Accessioni | P88946Primary (citable) accession number: P88946 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 1997 |
Last sequence update: | May 1, 1997 | |
Last modified: | September 29, 2021 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |