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Entry version 105 (08 May 2019)
Sequence version 1 (01 Jul 1997)
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Protein

Uncharacterized UPF0442 protein C16A10.01

Gene

SPAC16A10.01

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized UPF0442 protein C16A10.01
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPAC16A10.01
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPAC16A10.01

Schizosaccharomyces pombe database

More...
PomBasei
SPAC16A10.01

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei505 – 525HelicalSequence analysisAdd BLAST21
Transmembranei529 – 549HelicalSequence analysisAdd BLAST21
Transmembranei551 – 571HelicalSequence analysisAdd BLAST21
Transmembranei584 – 604HelicalSequence analysisAdd BLAST21
Transmembranei622 – 642HelicalSequence analysisAdd BLAST21
Transmembranei659 – 679HelicalSequence analysisAdd BLAST21
Transmembranei691 – 711HelicalSequence analysisAdd BLAST21
Transmembranei715 – 735HelicalSequence analysisAdd BLAST21
Transmembranei740 – 760HelicalSequence analysisAdd BLAST21
Transmembranei802 – 822HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001166421 – 830Uncharacterized UPF0442 protein C16A10.01Add BLAST830

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P87293

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P87293

PRoteomics IDEntifications database

More...
PRIDEi
P87293

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4896.SPAC16A10.01.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0442 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P87293

Identification of Orthologs from Complete Genome Data

More...
OMAi
KRCEFIL

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P87293

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010619 ThrE
IPR024528 ThrE_2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06738 ThrE, 1 hit
PF12821 ThrE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P87293-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVQLKLDPN SKNWLRQPDQ QPIQDSICTL PGPGSLLKKK IRKTEFRIDN
60 70 80 90 100
GLLGNTSPII NVESKIPFHR RANSTPEESR KRVSFSLTSN DGAKSDRSSQ
110 120 130 140 150
KSSNSRKSIR SQSRSRSSSV GSDSQASIQS GTNSEVVSDD EEDGNFASIP
160 170 180 190 200
ELHEDNEYHS NLATSSNPFS DGSSSKSASL TASSAAASPT VSFSPASTSE
210 220 230 240 250
NLTPTSSKSL ASNTSLVQSF NSASRSSSIS GNQYTYNLLG KSTDESPKIT
260 270 280 290 300
ISAGTSMSHF PSASSKLIQM RRHAHMNSEK CDPELLSHNE YFPMMKRGFI
310 320 330 340 350
SRFLCLFVSR DANVYIGPLE SSHAKPYRPF GSFVSRFTNR VASDLESQIP
360 370 380 390 400
DALEAVLTQN NDYDFNSFLH NMGYSRCYVD ENYHITIHVS SYERRVEFML
410 420 430 440 450
AVCEAMMLYG SPSHKIQQSL RIASRILQLP ATFLYLPDCM FVYFKKLEQY
460 470 480 490 500
SPDVFVVRVT SQTDLNRMVL VNEIFRRVMR DKLSAEDGTE VLRNITSFRP
510 520 530 540 550
LYRDWLVAFM HGVASASILP VVYGGGWRDM LIGFVLGLLL GIFRVYINPR
560 570 580 590 600
FFLFDSLFEV IISIILSFLG RAFGSISRYD KPVFCFAALV EGAITLILPG
610 620 630 640 650
YVVFCGVLEL QSKNIVAGGV RMLYAVIFSL FLSFGITIGS ALYGWMDKDA
660 670 680 690 700
TDADTCMSII AVSPYWYILL IPIFTLSLLI VTQSHPRQWP IQMFVACCGY
710 720 730 740 750
VVYYFSSLHF GASQISSAIG SFAVGCLGNM YSHFIKSSSF AVVLPAIFVL
760 770 780 790 800
VPSGFAAQGG VSAGLDTASQ ITSKNTTTNT TTVTTENSQN SSLEFGFTMV
810 820 830
EIAIGIAIGF LASSLTVYPF FGYRRKNMML
Length:830
Mass (Da):91,659
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i89910F885F9B602F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB10002.1
AB027818 Genomic DNA Translation: BAA87122.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T37766

NCBI Reference Sequences

More...
RefSeqi
NP_594041.1, NM_001019466.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC16A10.01.1; SPAC16A10.01.1:pep; SPAC16A10.01

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2542317

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC16A10.01

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB10002.1
AB027818 Genomic DNA Translation: BAA87122.1
PIRiT37766
RefSeqiNP_594041.1, NM_001019466.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4896.SPAC16A10.01.1

Proteomic databases

MaxQBiP87293
PaxDbiP87293
PRIDEiP87293

Genome annotation databases

EnsemblFungiiSPAC16A10.01.1; SPAC16A10.01.1:pep; SPAC16A10.01
GeneIDi2542317
KEGGispo:SPAC16A10.01

Organism-specific databases

EuPathDBiFungiDB:SPAC16A10.01
PomBaseiSPAC16A10.01

Phylogenomic databases

InParanoidiP87293
OMAiKRCEFIL
PhylomeDBiP87293

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P87293

Family and domain databases

InterProiView protein in InterPro
IPR010619 ThrE
IPR024528 ThrE_2
PfamiView protein in Pfam
PF06738 ThrE, 1 hit
PF12821 ThrE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYDN1_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P87293
Secondary accession number(s): Q9USE6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: May 8, 2019
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
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