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UniProtKB - P87207 (MNT3_CANAL)
Protein
Probable mannosyltransferase MNT3
Gene
MNT3
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Functioni
Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
GO - Molecular functioni
- alpha-1,2-mannosyltransferase activity Source: GO_Central
- mannosylphosphate transferase activity Source: CGD
GO - Biological processi
- cell wall mannoprotein biosynthetic process Source: GO_Central
- mannosylation Source: GO_Central
- protein N-linked glycosylation Source: CGD
- protein O-linked glycosylation Source: GO_Central
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Protein family/group databases
CAZyi | GT15, Glycosyltransferase Family 15 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:MNT3 Ordered Locus Names:CAALFM_CR05290WA ORF Names:CaO19.8624 |
Organismi | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Taxonomic identifieri | 237561 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Candida/Lodderomyces clade › Candida › |
Proteomesi |
|
Organism-specific databases
CGDi | CAL0000188769, MNT3 |
VEuPathDBi | FungiDB:CR_05290W_A |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type II membrane protein Curated
Golgi apparatus
- Golgi apparatus Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 4 | CytoplasmicSequence analysis | 4 | |
Transmembranei | 5 – 25 | Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 26 – 378 | LumenalSequence analysisAdd BLAST | 353 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000208249 | 1 – 378 | Probable mannosyltransferase MNT3Add BLAST | 378 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 73 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 149 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinFamily & Domainsi
Sequence similaritiesi
Belongs to the glycosyltransferase 15 family.Curated
Keywords - Domaini
Signal-anchor, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG4472, Eukaryota |
HOGENOMi | CLU_024327_4_2_1 |
InParanoidi | P87207 |
OrthoDBi | 948664at2759 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR002685, Glyco_trans_15 IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR31121, PTHR31121, 1 hit |
Pfami | View protein in Pfam PF01793, Glyco_transf_15, 1 hit |
PIRSFi | PIRSF018153, Glyco_trans_15, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
i Sequence
Sequence statusi: Complete.
P87207-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLWHLVFILI AILLLTFSPK IESLFKSFTI NKPTKTTCYQ YTTREQLKSI
60 70 80 90 100
LESDTHETNF CIEKPSISPP KTNSTLLMLC RNSDVFSVLE TIQNIQDRFN
110 120 130 140 150
DKYNYDYTFL NDVPFNYEFI YLVSSIIPHG KINFGLIPIE HWSYPSHINI
160 170 180 190 200
SLATEIRQNY ANVPYGDSES YRHMCRFYSG FFYKHELVKQ YQYYWRIEPG
210 220 230 240 250
IKIYCDIDYD VFEYMIINDK KYGFVISLFE YSETIPTLWN HVVQYINDNE
260 270 280 290 300
IKSELLPLLT NKYNWYNLCH FWSNFEIANL DIFNNDDYEN FFQYLDNLGG
310 320 330 340 350
FYYERWGDAP IHSIAIALFL QKKDIHWFEN IGYYHVPYLQ CPQDIDLYVK
360 370
NKCTCNPDED FTWSDLSCTN HFLNILHN
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 3 | W → R in CAA73985 (Ref. 1) Curated | 1 | |
Sequence conflicti | 18 | S → P in CAA73985 (Ref. 1) Curated | 1 | |
Sequence conflicti | 29 | T → I in CAA73985 (Ref. 1) Curated | 1 | |
Sequence conflicti | 55 | T → I in CAA73985 (Ref. 1) Curated | 1 | |
Sequence conflicti | 67 | I → T in CAA73985 (Ref. 1) Curated | 1 | |
Sequence conflicti | 81 – 85 | RNSDV → QNSDI in CAA73985 (Ref. 1) Curated | 5 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y13642 Genomic DNA Translation: CAA73985.1 CP017630 Genomic DNA Translation: AOW31254.1 |
RefSeqi | XP_710275.2, XM_705183.2 |
Genome annotation databases
GeneIDi | 3648123 |
KEGGi | cal:CAALFM_CR05290WA |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y13642 Genomic DNA Translation: CAA73985.1 CP017630 Genomic DNA Translation: AOW31254.1 |
RefSeqi | XP_710275.2, XM_705183.2 |
3D structure databases
SMRi | P87207 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 237561.P87207 |
Protein family/group databases
CAZyi | GT15, Glycosyltransferase Family 15 |
Genome annotation databases
GeneIDi | 3648123 |
KEGGi | cal:CAALFM_CR05290WA |
Organism-specific databases
CGDi | CAL0000188769, MNT3 |
VEuPathDBi | FungiDB:CR_05290W_A |
Phylogenomic databases
eggNOGi | KOG4472, Eukaryota |
HOGENOMi | CLU_024327_4_2_1 |
InParanoidi | P87207 |
OrthoDBi | 948664at2759 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR002685, Glyco_trans_15 IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR31121, PTHR31121, 1 hit |
Pfami | View protein in Pfam PF01793, Glyco_transf_15, 1 hit |
PIRSFi | PIRSF018153, Glyco_trans_15, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MNT3_CANAL | |
Accessioni | P87207Primary (citable) accession number: P87207 Secondary accession number(s): A0A1D8PSZ3, Q59KJ8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | March 15, 2017 | |
Last modified: | February 23, 2022 | |
This is version 107 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Candida albicans
Candida albicans: entries and gene names - SIMILARITY comments
Index of protein domains and families