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Entry version 117 (25 May 2022)
Sequence version 1 (01 Jul 1997)
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Protein

Uncharacterized protein C57A7.05

Gene

SPAC57A7.05

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C57A7.05
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPAC57A7.05
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPAC57A7.05

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPAC57A7.05

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei209 – 229HelicalSequence analysisAdd BLAST21
Transmembranei241 – 261HelicalSequence analysisAdd BLAST21
Transmembranei267 – 287HelicalSequence analysisAdd BLAST21
Transmembranei328 – 348HelicalSequence analysisAdd BLAST21
Transmembranei361 – 381HelicalSequence analysisAdd BLAST21
Transmembranei387 – 407HelicalSequence analysisAdd BLAST21
Transmembranei917 – 937HelicalSequence analysisAdd BLAST21
Transmembranei975 – 995HelicalSequence analysisAdd BLAST21
Transmembranei997 – 1017HelicalSequence analysisAdd BLAST21
Transmembranei1021 – 1041HelicalSequence analysisAdd BLAST21
Transmembranei1066 – 1086HelicalSequence analysisAdd BLAST21
Transmembranei1275 – 1295HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001166401 – 1337Uncharacterized protein C57A7.05Add BLAST1337

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P87136

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P87136

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
279337, 1 interactor

STRING: functional protein association networks

More...
STRINGi
4896.SPAC57A7.05.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
P87136

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 94DisorderedSequence analysisAdd BLAST94
Regioni119 – 174DisorderedSequence analysisAdd BLAST56
Regioni623 – 662DisorderedSequence analysisAdd BLAST40
Regioni868 – 894DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 42Polar residuesSequence analysisAdd BLAST42
Compositional biasi61 – 94Polar residuesSequence analysisAdd BLAST34
Compositional biasi123 – 160Polar residuesSequence analysisAdd BLAST38

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4711, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003918_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P87136

Identification of Orthologs from Complete Genome Data

More...
OMAi
WAWSCLG

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P87136

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018823, ArAE_2_N
IPR018820, BRE4-related_DUF2421

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10334, ArAE_2, 1 hit
PF10337, ArAE_2_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P87136-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPTSGAPSNL DRANAQLSNT SSTESSSSNN SSTASGSRHV KIESNRVSLP
60 70 80 90 100
PLKIQKGSFP AIRQPTESST HFQSSHSVSN AHNQSPLNQS QSSANPVTFE
110 120 130 140 150
IADEPSPSFN HSFFEKDNAR DIPQQPSHSQ NPSSSSSSSS SQSSQHSTHL
160 170 180 190 200
QFQIPSNEKK SLDDPSPRRK PSFFSKSNLK RKYRYLKNPD AWNLPPSLQF
210 220 230 240 250
IPKNLNRKGL KPVIRAAINS WIAFLLVLAR HTNRVLGMSS FFVVITSILV
260 270 280 290 300
PAMEPIAPML WKTLFQFLLL FSAYAWTVLA AKLATVARGS PSREASLAQA
310 320 330 340 350
VSEGFVCPDP SQGFNYCIRE AVFQGYFVRP LPSIIWALFE FSAVALFIRL
360 370 380 390 400
KMKYPPLNFP CVFSIICTAV SANMGPMYPY FYPRIGLFFI VPNCVQTGIT
410 420 430 440 450
IGCTLFILPE TCNHAYNTML CKLTEDTSSF LKRQTEMLSH SPASSHWASF
460 470 480 490 500
SSLENEIANL KNLLSKMKST ELFLDMEFSY GRLKGEDLVS IQRIFKKTIL
510 520 530 540 550
RLSAFSYFQR LIDHNMQIYD DETIQKAGEA TVSSWLNTPA LSAASARTSS
560 570 580 590 600
GRNSSESDRV SYFGLAPVNA TTQDSERNGE EIRRLASKQL NVPVNNNFRT
610 620 630 640 650
VGYASPSNAS TASFNDIVQR GRSHVRTGSN NSEAPLAAKT STTKRNGDLL
660 670 680 690 700
EPQSPSLRSH KSRLHLPSSL GKFYKKRKKS YKPVGVLEAQ QYLALESRLP
710 720 730 740 750
FNKPQFLDSL LSILKNSSGD LFDQAIYSLD ALNAWLVELN HDRIKKIFSK
760 770 780 790 800
RDQKAAGRDR LKLIKLHYDH LSQALHEYER EKCFDVRKPY ESLFQNQDVQ
810 820 830 840 850
QFYMHSLRSL FVVYYYESHL MQAVRGILQI LETVIDLEER RPIRRLWWPL
860 870 880 890 900
RSIRRSLLSQ LTGHQGDYDE NIHNDVDKDM NQSSTQPRDP DADHPSSLYH
910 920 930 940 950
ICGYRLTKFF KSIFRPMNVF VLKVGTLAVI CTIPAFCRSS AGWYYRNRGL
960 970 980 990 1000
WAVILAIMSL QRFTADTVYG YLMRIFGTFF GAILGMVIWY TGSGHGLGNA
1010 1020 1030 1040 1050
YGLAAVWGAA IPFIQFIRVH FVILTPMPAV IFCVTAALTV TYSWKSNHEP
1060 1070 1080 1090 1100
GVVTLGIGWD VAYRRFLTVA AGITVAFIFS FLPQPRTAKY AVRKNIGNTL
1110 1120 1130 1140 1150
IDIGSIHCEI SNFARRPVHN HIDPDIQSKV LNLSNTIQSL IGRLNMVNFE
1160 1170 1180 1190 1200
PSFKGRWPME KYQLLCKTQL ELVDLLNSLM TTITTLEDRW LFALLYRVGW
1210 1220 1230 1240 1250
LDHKFVADQL AVLYMSSNAL QTGNPLPQVV PSPLVDRFFT TSGDVFLPPG
1260 1270 1280 1290 1300
LNDAPVPIPK AMEYELLNNM QYLNFAVGCT IAYAVVNHID RIMFITKSLC
1310 1320 1330
GEIFEIDKWP FHFDDEYLYT CHPTNSPDQR KSPHDLV
Length:1,337
Mass (Da):150,849
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA549BC8E00D08791
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB08763.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T38949

NCBI Reference Sequences

More...
RefSeqi
NP_593376.1, NM_001018808.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC57A7.05.1; SPAC57A7.05.1:pep; SPAC57A7.05

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2542893

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC57A7.05

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB08763.1
PIRiT38949
RefSeqiNP_593376.1, NM_001018808.2

3D structure databases

AlphaFoldDBiP87136
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi279337, 1 interactor
STRINGi4896.SPAC57A7.05.1

PTM databases

iPTMnetiP87136

Proteomic databases

PaxDbiP87136

Genome annotation databases

EnsemblFungiiSPAC57A7.05.1; SPAC57A7.05.1:pep; SPAC57A7.05
GeneIDi2542893
KEGGispo:SPAC57A7.05

Organism-specific databases

PomBaseiSPAC57A7.05
VEuPathDBiFungiDB:SPAC57A7.05

Phylogenomic databases

eggNOGiKOG4711, Eukaryota
HOGENOMiCLU_003918_2_0_1
InParanoidiP87136
OMAiWAWSCLG
PhylomeDBiP87136

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P87136

Family and domain databases

InterProiView protein in InterPro
IPR018823, ArAE_2_N
IPR018820, BRE4-related_DUF2421
PfamiView protein in Pfam
PF10334, ArAE_2, 1 hit
PF10337, ArAE_2_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYDM5_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P87136
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: May 25, 2022
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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