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UniProtKB - P87122 (YDL6_SCHPO)
Protein
Putative cation exchanger C3A12.06c
Gene
SPAC3A12.06c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Putative cation exchanger.
By similarityGO - Molecular functioni
- cation transmembrane transporter activity Source: PomBase
GO - Biological processi
- cation transmembrane transport Source: PomBase
- cation transport Source: GO_Central
- cellular calcium ion homeostasis Source: GO_Central
Keywordsi
Biological process | Ion transport, Transport |
Enzyme and pathway databases
Reactomei | R-SPO-425561, Sodium/Calcium exchangers R-SPO-8949215, Mitochondrial calcium ion transport |
Names & Taxonomyi
Protein namesi | Recommended name: Putative cation exchanger C3A12.06c |
Gene namesi | ORF Names:SPAC3A12.06c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPAC3A12.06c |
VEuPathDBi | FungiDB:SPAC3A12.06c |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 13 – 33 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 109 – 129 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 138 – 158 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 182 – 202 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 213 – 233 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 239 – 258 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 528 – 548 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 551 – 571 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 580 – 600 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 609 – 629 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 649 – 669 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 690 – 710 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 718 – 738 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000317130 | 1 – 743 | Putative cation exchanger C3A12.06cAdd BLAST | 743 |
Proteomic databases
PaxDbi | P87122 |
PTM databases
iPTMneti | P87122 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 279612, 17 interactors |
STRINGi | 4896.SPAC3A12.06c.1 |
Structurei
3D structure databases
AlphaFoldDBi | P87122 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2399, Eukaryota |
HOGENOMi | CLU_004979_2_1_1 |
InParanoidi | P87122 |
OMAi | MNIANEV |
PhylomeDBi | P87122 |
Family and domain databases
Gene3Di | 1.20.1420.30, 2 hits |
InterProi | View protein in InterPro IPR004837, NaCa_Exmemb IPR044880, NCX_ion-bd_dom_sf |
Pfami | View protein in Pfam PF01699, Na_Ca_ex, 2 hits |
i Sequence
Sequence statusi: Complete.
P87122-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKTSCFLKK YRLILLWCIL GIAYILFWTH RISKAFASVS STSDSTVHLF
60 70 80 90 100
ERGNTLNDSN DQILLTCNDI KNITPANQCR FAKAYCKGEA SGFFDYVEFY
110 120 130 140 150
FCTINSLRFP VLSIIVGWLI FLFITIGISA SDFFSTNLVT ISWLLQLPDS
160 170 180 190 200
VVGVTFLALG NGSPDILSTF AAVRVNSGGM AIGELLGSAF FIVAIVAGSV
210 220 230 240 250
CLIKPFKIPR RHFLRDVAFL TGTILLVIMF VLHDGSLSIW QSLVMILYYL
260 270 280 290 300
LYVLFVFFSG SSGVSVVITD ENYLPVSLPV YSPVLNSFDD SDSYSSTDSE
310 320 330 340 350
LSEEAFLLPA QASRKTQKIH YINDNDPSNS YSSYQHSHVH DFIHKNNTHS
360 370 380 390 400
NRVLSQSSGP IVRPSLLAAL DFRSSNEEQH PGLRSLDPLN IQDGDLTMHP
410 420 430 440 450
MHIRHSQSDF YPSGINTPVS GINYPNLGFS ANNSVQSLVS EIFRHPTHTD
460 470 480 490 500
EDFPLPSPSL SSLLFPTLRN FAKKSWYEKL MDVLAVPSVL IFTLALPVYQ
510 520 530 540 550
CPRLAVDPIY HMDVSNCNPS KPTWSRKLRL LQCVFVPFAF VTFSITGGNR
560 570 580 590 600
LYIYAASSVF SILCITALYY YTDEEKPPKF LPWVSFIGFV LGIIWISTIA
610 620 630 640 650
NEVVGILRAL GVIFNLNESI LGLTVFAAGN SLSDLIADIM IARSGFPEMA
660 670 680 690 700
MGGVFGGPTL NILIGIGISS FYSSISNHGN DSVIEIPHSL SITAYFLLAC
710 720 730 740
LLLLLIYVPL NRFRVNRVLG LLLFILYIVG TSTNIVVELL KDK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB08751.1 |
PIRi | T38674 |
RefSeqi | NP_593332.1, NM_001018763.2 |
Genome annotation databases
EnsemblFungii | SPAC3A12.06c.1; SPAC3A12.06c.1:pep; SPAC3A12.06c |
GeneIDi | 2543183 |
KEGGi | spo:SPAC3A12.06c |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB08751.1 |
PIRi | T38674 |
RefSeqi | NP_593332.1, NM_001018763.2 |
3D structure databases
AlphaFoldDBi | P87122 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 279612, 17 interactors |
STRINGi | 4896.SPAC3A12.06c.1 |
PTM databases
iPTMneti | P87122 |
Proteomic databases
PaxDbi | P87122 |
Genome annotation databases
EnsemblFungii | SPAC3A12.06c.1; SPAC3A12.06c.1:pep; SPAC3A12.06c |
GeneIDi | 2543183 |
KEGGi | spo:SPAC3A12.06c |
Organism-specific databases
PomBasei | SPAC3A12.06c |
VEuPathDBi | FungiDB:SPAC3A12.06c |
Phylogenomic databases
eggNOGi | KOG2399, Eukaryota |
HOGENOMi | CLU_004979_2_1_1 |
InParanoidi | P87122 |
OMAi | MNIANEV |
PhylomeDBi | P87122 |
Enzyme and pathway databases
Reactomei | R-SPO-425561, Sodium/Calcium exchangers R-SPO-8949215, Mitochondrial calcium ion transport |
Miscellaneous databases
PROi | PR:P87122 |
Family and domain databases
Gene3Di | 1.20.1420.30, 2 hits |
InterProi | View protein in InterPro IPR004837, NaCa_Exmemb IPR044880, NCX_ion-bd_dom_sf |
Pfami | View protein in Pfam PF01699, Na_Ca_ex, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | YDL6_SCHPO | |
Accessioni | P87122Primary (citable) accession number: P87122 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 5, 2008 |
Last sequence update: | July 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families