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Entry version 69 (12 Aug 2020)
Sequence version 1 (15 Dec 2009)
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Protein

Hydroxyacyl-thioester dehydratase type 2, mitochondrial

Gene

HTD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis.1 Publication

Miscellaneous

This protein is produced by a bicistronic gene which also produces the RPP14 protein from an overlapping reading frame.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyase
Biological processFatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P86397

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-75105, Fatty acyl-CoA biosynthesis

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000001096

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hydroxyacyl-thioester dehydratase type 2, mitochondrial1 Publication (EC:4.2.1.-)
Short name:
HsHTD21 Publication
Alternative name(s):
3-hydroxyacyl-[acyl-carrier-protein] dehydrataseBy similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HTD21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000255154.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:53111, HTD2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P86397

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi62D → A: Abolishes ability to complement a htd2-delta mutant yeast. 1 Publication1
Mutagenesisi67H → A: Abolishes ability to complement a htd2-delta mutant yeast. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
109703458

Open Targets

More...
OpenTargetsi
ENSG00000255154

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P86397, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
HTD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
281312149

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – ?Mitochondrion1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000390489? – 168Hydroxyacyl-thioester dehydratase type 2, mitochondrial1 Publication

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P86397

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P86397

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P86397

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P86397

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P86397

PeptideAtlas

More...
PeptideAtlasi
P86397

PRoteomics IDEntifications database

More...
PRIDEi
P86397

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57772

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart and liver. Expressed at lower levels in skeletal muscle, spleen, kidney and placenta.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000255154, Expressed in muscle of leg and 121 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P86397, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P86397, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000255154, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
P86397, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000481593

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P86397, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1168
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P86397

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P86397

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini41 – 146MaoC-likeAdd BLAST106

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the HTD2 family.Sequence analysis

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1206, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000065109

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_094876_3_4_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P86397

KEGG Orthology (KO)

More...
KOi
K22540

Identification of Orthologs from Complete Genome Data

More...
OMAi
PGPGCIY

Database of Orthologous Groups

More...
OrthoDBi
1326407at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P86397

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029069, HotDog_dom_sf
IPR002539, MaoC-like_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01575, MaoC_dehydratas, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54637, SSF54637, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P86397-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFPLISSHHL WWGGLRRTVC LNLPVLTLQH FQHMHIKVGD RAELRRAFTQ
60 70 80 90 100
TDVATFSELT GDVNPLHLNE DFAKHTKFGN TIVHGVLING LISALLGTKM
110 120 130 140 150
PGPGCVFLSQ EISFPAPLYI GEVVLASAEV KKLKRFIAII AVSCSVIESK
160
KTVMEGWVKV MVPEASKS
Length:168
Mass (Da):18,559
Last modified:December 15, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6AAB9445C17F4FD7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WTC8A0A087WTC8_HUMAN
Hydroxyacyl-thioester dehydratase t...
HTD2
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WUW1A0A087WUW1_HUMAN
Hydroxyacyl-thioester dehydratase t...
HTD2
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYB6A0A087WYB6_HUMAN
Hydroxyacyl-thioester dehydratase t...
HTD2
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC098479 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS87096.1

NCBI Reference Sequences

More...
RefSeqi
NP_001335641.1, NM_001348712.1
NP_001335642.1, NM_001348713.1
NP_001335643.1, NM_001348714.1
NP_001335644.1, NM_001348715.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000461393; ENSP00000484277; ENSG00000255154
ENST00000477305; ENSP00000481593; ENSG00000255154
ENST00000481972; ENSP00000482940; ENSG00000255154

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
109703458

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:109703458

UCSC genome browser

More...
UCSCi
uc010hni.4, human

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098479 mRNA No translation available.
CCDSiCCDS87096.1
RefSeqiNP_001335641.1, NM_001348712.1
NP_001335642.1, NM_001348713.1
NP_001335643.1, NM_001348714.1
NP_001335644.1, NM_001348715.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3IR3X-ray1.99A/B23-168[»]
SMRiP86397
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiP86397, 1 interactor
STRINGi9606.ENSP00000481593

Chemistry databases

SwissLipidsiSLP:000001096

Polymorphism and mutation databases

BioMutaiHTD2
DMDMi281312149

Proteomic databases

EPDiP86397
jPOSTiP86397
MassIVEiP86397
MaxQBiP86397
PaxDbiP86397
PeptideAtlasiP86397
PRIDEiP86397
ProteomicsDBi57772

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
69913, 16 antibodies

Genome annotation databases

EnsembliENST00000461393; ENSP00000484277; ENSG00000255154
ENST00000477305; ENSP00000481593; ENSG00000255154
ENST00000481972; ENSP00000482940; ENSG00000255154
GeneIDi109703458
KEGGihsa:109703458
UCSCiuc010hni.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
109703458
DisGeNETi109703458
EuPathDBiHostDB:ENSG00000255154.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
HTD2
HGNCiHGNC:53111, HTD2
HPAiENSG00000255154, Low tissue specificity
neXtProtiNX_P86397
OpenTargetsiENSG00000255154

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1206, Eukaryota
GeneTreeiENSGT00530000065109
HOGENOMiCLU_094876_3_4_1
InParanoidiP86397
KOiK22540
OMAiPGPGCIY
OrthoDBi1326407at2759
PhylomeDBiP86397

Enzyme and pathway databases

PathwayCommonsiP86397
ReactomeiR-HSA-75105, Fatty acyl-CoA biosynthesis

Miscellaneous databases

EvolutionaryTraceiP86397

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
109703458
PharosiP86397, Tdark

Protein Ontology

More...
PROi
PR:P86397
RNActiP86397, protein

Gene expression databases

BgeeiENSG00000255154, Expressed in muscle of leg and 121 other tissues
ExpressionAtlasiP86397, baseline and differential
GenevisibleiP86397, HS

Family and domain databases

InterProiView protein in InterPro
IPR029069, HotDog_dom_sf
IPR002539, MaoC-like_dom
PfamiView protein in Pfam
PF01575, MaoC_dehydratas, 1 hit
SUPFAMiSSF54637, SSF54637, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHTD2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P86397
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2009
Last sequence update: December 15, 2009
Last modified: August 12, 2020
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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