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Protein

Transmembrane protein 170B

Gene

Tmem170b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 170BImported
Gene namesi
Name:Tmem170bImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:3647046 Tmem170b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 37ExtracellularSequence analysisAdd BLAST37
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Topological domaini59 – 68CytoplasmicSequence analysis10
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Topological domaini90 – 104ExtracellularSequence analysisAdd BLAST15
Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
Topological domaini126 – 132CytoplasmicSequence analysis7

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003549761 – 132Transmembrane protein 170BAdd BLAST132

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi12N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP86050
PRIDEiP86050

PTM databases

PhosphoSitePlusiP86050

Expressioni

Gene expression databases

BgeeiENSMUSG00000087370
ExpressionAtlasiP86050 baseline and differential
GenevisibleiP86050 MM

Interactioni

Subunit structurei

Interacts with CTNNB1.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM170 family.Sequence analysis

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4349 Eukaryota
ENOG4111MVH LUCA
GeneTreeiENSGT00390000002101
HOVERGENiHBG108536
InParanoidiP86050
OMAiLWCLFSS
OrthoDBiEOG091G0V4L
PhylomeDBiP86050
TreeFamiTF314615

Family and domain databases

InterProiView protein in InterPro
IPR019334 Transmembrane_pr_170
PANTHERiPTHR22779 PTHR22779, 1 hit
PfamiView protein in Pfam
PF10190 Tmemb_170, 1 hit

Sequencei

Sequence statusi: Complete.

P86050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAEGADHSM INLSVQQVLS LWAHGTVLRN LTEMWYWIFL WALFSSLFVH
60 70 80 90 100
GAAGVLMFVM LQRHRQGRVI SIIAVSIGFL ASVTGAMITS AAVAGIYRVA
110 120 130
GKNMAPLEAL VWGVGQTVLT LIISFSRILA TL
Length:132
Mass (Da):14,416
Last modified:November 25, 2008 - v1
Checksum:iD290011654AE49ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133159 Genomic DNA No translation available.
CCDSiCCDS49248.1
RefSeqiNP_001157044.1, NM_001163572.1
UniGeneiMm.259830
Mm.408884

Genome annotation databases

EnsembliENSMUST00000129449; ENSMUSP00000131144; ENSMUSG00000087370
GeneIDi621976
KEGGimmu:621976
UCSCiuc011yyr.1 mouse

Similar proteinsi

Entry informationi

Entry nameiT170B_MOUSE
AccessioniPrimary (citable) accession number: P86050
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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