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Entry version 53 (11 Dec 2019)
Sequence version 1 (03 Apr 2007)
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Protein

Respiratory nitrate reductase alpha chain

Gene

narG

Organism
Bradyrhizobium sp.
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The nitrate reductase enzyme complex allows Bradyrhizobium sp. USDA 3045 to use nitrate as an electron acceptor during anaerobic growth. The alpha chain is the actual site of nitrate reduction.By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by micromolar concentrations of azide.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi29Iron-sulfur (4Fe-4S); via pros nitrogenBy similarity1
Metal bindingi33Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi37Iron-sulfur (4Fe-4S)By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Nitrate assimilation, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding, Molybdenum

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
1.7.99.4 930

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Respiratory nitrate reductase alpha chain (EC:1.7.5.1)
Alternative name(s):
Respiratory membrane-bound nitrate reductase subunit alpha
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:narG
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBradyrhizobium sp.
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri376 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobiumunclassified Bradyrhizobium

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

  • Cell membrane 1 Publication
  • Cytoplasm 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002837781 – ›902Respiratory nitrate reductase alpha chainAdd BLAST›902

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced by anaerobiosis, there is no significant expression in an aerobic environment. Expression is further induced in the presence of nitrate or nitrite.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterotrimer composed of an alpha, a beta and a gamma chain. Alpha and beta are catalytic chains; gamma chains are involved in binding the enzyme complex to the cytoplasmic membrane.

1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P85097

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009010 Asp_de-COase-like_dom_sf
IPR006657 MoPterin_dinucl-bd_dom
IPR006656 Mopterin_OxRdtase
IPR006655 Mopterin_OxRdtase_prok_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00384 Molybdopterin, 2 hits
PF01568 Molydop_binding, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50692 SSF50692, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00490 MOLYBDOPTERIN_PROK_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragments.

P85097-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
FSPIDRYNDN HTQETYEDRE WENVYRSTHG VNCTGSCSWK DGIVTWEGQE
60 70 80 90 100
LNYPTTGPDM PDFEPRGASY SWYLYSANRG VLWSMWQEEL QNNESPLDAW
110 120 130 140 150
KSSWQEVNEL IAASNVYTVK TYGPDRVAGF SPIPAMSMVS YASGARTPDA
160 170 180 190 200
HFFTEVRVVS VSPDFAESTK LCDLWLAPKQ GTDAAMALAM GHVMLREFHL
210 220 230 240 250
DNPSDYFLNY CRQYTDFPFL VTLSKQKGDQ FVADRAADLV DALGQENNPE
260 270 280 290 300
WKPVLWNENT NDFATPHGTM GSRGKWNLEQ RLEDEETGEK LSVLGIEDEI
310 320 330 340 350
GTVRLQLADG STALVTTVYD LTMANYGLER GLGGQEPKDF NDDVPFTPAW
360 370 380 390 400
QEKITGVPRE LIIQIAREFA DNADKTHGRA VLNLVLLVGA QGVNGGGWAH
410 420 430 440 450
YVGQEKLRPA EGWQTIAMAK HMNSTSYFYN HSSQWRYETV TAQELLSPMA
460 470 480 490 500
DKYQHHGDYN VLAARMGWLP SAPQLGTNPL RQAGMSPVDY TVKFAAEQPE
510 520 530 540 550
NGKNHPRNLF VWRSNLLGSS GKGHEYMLKY LLGTENGIQG KQGGVKPEEV
560 570 580 590 600
EWKLSSTCLY SDIVLPTATW YEKDDMNTSD MHPFIHPLSA AVDPAWESKS
610 620 630 640 650
DWDIFTSLSK KFSEVCVGHL GKETDVVTLP IQHDSAAELA QPLDVKDWKG
660 670 680 690 700
ECEPIPGKTM PQIHVVERDY PATYERFTSI GPLMEKGIAW NTQSEMDLLR
710 720 730 740 750
AWAALSEFTG RDHTHLALNK EDEKFRDIQA QPRTVITSPA FTGSEKQSFY
760 770 780 790 800
LDHDMMKDFG ESLLVYRPPI DTRKSRPEVE GKEITLNYLT PHNKGGPIVW
810 820 830 840 850
ISETDARDLG IEDNDWIEVF NSNGALTARV PAGMTMMYHA QERGGIHNSV
860 870 880 890 900
TRPTHMIGGY AQLAYGFNYY GTVGSNRDEF VVVRNINWLD GEGNDQVQES

VK
Length:902
Mass (Da):101,519
Last modified:April 3, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i93540162AA633C66
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used to indicate that two residues in a sequence are not consecutive and that there is an undetermined number of unsequenced residues between them.<p><a href='/help/non_cons' target='_top'>More...</a></p>Non-adjacent residuesi6 – 71 Publication2
Non-adjacent residuesi26 – 271 Publication2
Non-adjacent residuesi40 – 411 Publication2
Non-adjacent residuesi66 – 671 Publication2
Non-adjacent residuesi79 – 801 Publication2
Non-adjacent residuesi101 – 1021 Publication2
Non-adjacent residuesi120 – 1211 Publication2
Non-adjacent residuesi126 – 1271 Publication2
Non-adjacent residuesi146 – 1471 Publication2
Non-adjacent residuesi157 – 1581 Publication2
Non-adjacent residuesi170 – 1711 Publication2
Non-adjacent residuesi179 – 1801 Publication2
Non-adjacent residuesi196 – 1971 Publication2
Non-adjacent residuesi212 – 2131 Publication2
Non-adjacent residuesi225 – 2261 Publication2
Non-adjacent residuesi235 – 2361 Publication2
Non-adjacent residuesi252 – 2531 Publication2
Non-adjacent residuesi273 – 2741 Publication2
Non-adjacent residuesi281 – 2821 Publication2
Non-adjacent residuesi290 – 2911 Publication2
Non-adjacent residuesi304 – 3051 Publication2
Non-adjacent residuesi330 – 3311 Publication2
Non-adjacent residuesi338 – 3391 Publication2
Non-adjacent residuesi353 – 3541 Publication2
Non-adjacent residuesi359 – 3601 Publication2
Non-adjacent residuesi367 – 3681 Publication2
Non-adjacent residuesi379 – 3801 Publication2
Non-adjacent residuesi406 – 4071 Publication2
Non-adjacent residuesi420 – 4211 Publication2
Non-adjacent residuesi436 – 4371 Publication2
Non-adjacent residuesi452 – 4531 Publication2
Non-adjacent residuesi465 – 4661 Publication2
Non-adjacent residuesi481 – 4821 Publication2
Non-adjacent residuesi493 – 4941 Publication2
Non-adjacent residuesi507 – 5081 Publication2
Non-adjacent residuesi513 – 5141 Publication2
Non-adjacent residuesi522 – 5231 Publication2
Non-adjacent residuesi529 – 5301 Publication2
Non-adjacent residuesi541 – 5421 Publication2
Non-adjacent residuesi553 – 5541 Publication2
Non-adjacent residuesi573 – 5741 Publication2
Non-adjacent residuesi599 – 6001 Publication2
Non-adjacent residuesi610 – 6111 Publication2
Non-adjacent residuesi622 – 6231 Publication2
Non-adjacent residuesi649 – 6501 Publication2
Non-adjacent residuesi658 – 6591 Publication2
Non-adjacent residuesi668 – 6691 Publication2
Non-adjacent residuesi676 – 6771 Publication2
Non-adjacent residuesi686 – 6871 Publication2
Non-adjacent residuesi700 – 7011 Publication2
Non-adjacent residuesi711 – 7121 Publication2
Non-adjacent residuesi724 – 7251 Publication2
Non-adjacent residuesi733 – 7341 Publication2
Non-adjacent residuesi746 – 7471 Publication2
Non-adjacent residuesi757 – 7581 Publication2
Non-adjacent residuesi773 – 7741 Publication2
Non-adjacent residuesi782 – 7831 Publication2
Non-adjacent residuesi794 – 7951 Publication2
Non-adjacent residuesi807 – 8081 Publication2
Non-adjacent residuesi829 – 8301 Publication2
Non-adjacent residuesi843 – 8441 Publication2
Non-adjacent residuesi852 – 8531 Publication2
Non-adjacent residuesi884 – 8851 Publication2
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei9021 Publication1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiP85097
ModBaseiSearch...

Enzyme and pathway databases

BRENDAi1.7.99.4 930

Family and domain databases

InterProiView protein in InterPro
IPR009010 Asp_de-COase-like_dom_sf
IPR006657 MoPterin_dinucl-bd_dom
IPR006656 Mopterin_OxRdtase
IPR006655 Mopterin_OxRdtase_prok_CS
PfamiView protein in Pfam
PF00384 Molybdopterin, 2 hits
PF01568 Molydop_binding, 1 hit
SUPFAMiSSF50692 SSF50692, 1 hit
PROSITEiView protein in PROSITE
PS00490 MOLYBDOPTERIN_PROK_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNARG_BRASZ
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P85097
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: December 11, 2019
This is version 53 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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