UniProtKB - P84902 (CASSI_CORCC)
Protein
Cassiicolin
Gene
N/A
Organism
Corynespora cassiicola (Target leaf spot disease fungus) (Helminthosporium cassiicola)
Status
Functioni
Toxin, essential for pathogenicity. Causes symptoms of Corynespora leaf fall disease (CLF) in rubber trees, including chlorosis, development of brown spots and necrosis. Alters leaf cell ultrastructure, causing plasmolysis in most cell types. In extreme cases the plasmolysis leads to disruption of the plasma membrane. Also affects chloroplast structure, causing lamellae distortion and reduced thylakoids stacking together. Causes accumulation of starch grains. Does not affect the nucleus or mitochondria. Toxic to N.tabacum, L.esculentum, S.ionantha, F.lyrata, P.violacea, S.melongena, and G.max. Not toxic to P.alba, G.hirsutum, P.acerifolia, R.pseudoacacia, T.zebrina, M.alba, and Q.ilex.2 Publications
GO - Molecular functioni
- toxin activity Source: UniProtKB-KW
Keywordsi
Molecular function | Toxin |
Names & Taxonomyi
Protein namesi | Recommended name: Cassiicolin |
Organismi | Corynespora cassiicola (Target leaf spot disease fungus) (Helminthosporium cassiicola) |
Taxonomic identifieri | 59586 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Corynesporascaceae › Corynespora |
Subcellular locationi
Extracellular region or secreted
- Secreted 1 Publication
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
PeptideiPRO_0000279697 | 1 – 27 | Cassiicolin1 PublicationAdd BLAST | 27 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | Pyrrolidone carboxylic acid2 Publications | 1 | |
Glycosylationi | 2 | O-linked (Man) threonine2 Publications | 1 | |
Disulfide bondi | 3 ↔ 18 | 1 Publication | ||
Disulfide bondi | 6 ↔ 27 | 1 Publication | ||
Disulfide bondi | 14 ↔ 24 | 1 Publication |
Post-translational modificationi
O-glycosylated with 3-O-methyl-O-alpha-D-mannopyranosyl.2 Publications
Keywords - PTMi
Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acidPTM databases
iPTMneti | P84902 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P84902 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P84902 |
i Sequence
Sequence statusi: Complete.
Mass spectrometryi
Molecular mass is 2884.96 Da. Determined by ESI. 1 Publication
Similar proteinsi
Cross-referencesi
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2HGO | NMR | - | A | 2-27 | [»] | |
SMRi | P84902 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
PTM databases
iPTMneti | P84902 |
Protocols and materials databases
ABCDi | P84902, 1 sequenced antibody |
Miscellaneous databases
EvolutionaryTracei | P84902 |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CASSI_CORCC | |
Accessioni | P84902Primary (citable) accession number: P84902 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 6, 2007 |
Last sequence update: | March 6, 2007 | |
Last modified: | June 17, 2020 | |
This is version 37 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencingDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references