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Protein

Photoactivated adenylate cyclase subunit alpha-like protein FB

Gene

pacA

Organism
Euglena gracilis
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

The FB strain is deficient in phototaxis. It is not known if this is due to defective adenylate cyclase activity or defective BLUF domains in this protein. In wild-type E.gracilis, photoactivated adenylate cyclase is found in the paraxonemal bodies (PABs). PABs are not visible in all cells in this strain, and are smaller than in wild-type.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Photoactivated adenylate cyclase subunit alpha-like protein FB
Gene namesi
Name:pacAImported
OrganismiEuglena gracilis
Taxonomic identifieri3039 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaEuglenidaEuglenalesEuglenaceaeEuglena

Subcellular locationi

  • flagellum 1 Publication
  • Note: Paraxonemal body. And paraxonemal bodies (PABs).

GO - Cellular componenti

  • intracellular Source: GOC
  • motile cilium Source: UniProtKB

Keywords - Cellular componenti

Cell projection, Cilium, Flagellum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001957201 – 1019Photoactivated adenylate cyclase subunit alpha-like protein FBAdd BLAST1019

Proteomic databases

PRIDEiP84737

Interactioni

Subunit structurei

Heterotetramer of two alpha and two beta subunits.By similarity

Structurei

3D structure databases

ProteinModelPortaliP84737
SMRiP84737
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 148BLUF 1PROSITE-ProRule annotationAdd BLAST94
Domaini204 – 332Guanylate cyclase 1PROSITE-ProRule annotationAdd BLAST129
Domaini467 – 559BLUF 2PROSITE-ProRule annotationAdd BLAST93
Domaini615 – 744Guanylate cyclase 2PROSITE-ProRule annotationAdd BLAST130

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di3.30.70.1230, 2 hits
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR036046 Acylphosphatase-like_dom_sf
IPR007024 BLUF_domain
IPR032675 LRR_dom_sf
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF04940 BLUF, 2 hits
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM01034 BLUF, 2 hits
SUPFAMiSSF54975 SSF54975, 2 hits
SSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS50925 BLUF, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

P84737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYILVWKEGQ QIRTFQDLEE CGQFQTASNI TDGQIFSINV TPTMSKGGET
60 70 80 90 100
GETQLRRLMY LSASTEPEKC YAEYLADMAH VATLRNKQIG VSGFLLYSSP
110 120 130 140 150
FFFEVIEGTD EELDFLFAKI SADPRHVRCI VLANGPCTGR LYGEWHMKDS
160 170 180 190 200
HIDNITKHPA IKTILFQIAR SFSCMWSYLP KNAANMLLLG KNPNKQAPEP
210 220 230 240 250
MSVVVTFIYL VEFSSILAHP GQTEQCADIL AAFVDACVRN VEGTGAQVAK
260 270 280 290 300
FITGICIAYW PINRAEDALI GLQQLSEDLA ELRSQQRPGS ALSLIYSRCG
310 320 330 340 350
VHYGRALLCN AGFRKADFTL LGDCINTASR ITSLSVKLKV PLLLSFEVRC
360 370 380 390 400
VLGDEMREVL ETSGLHKVKG RDQPVQVYQF NARELDSAMV RAKIEQLNPG
410 420 430 440 450
SYRALCPVKP YESLLPAQRP PIFDDTPREN QPKLSQVQRR DSLVDRLSLI
460 470 480 490 500
AKLAFPTSMM AGGEGQLITL TYISQAAHPM TRLDLASIQR IAFARNESSN
510 520 530 540 550
ITGSLLHVSG LFVQTLEGPK GAVVSLYLKI RQDKRHKDVV ADFMAPSEGR
560 570 580 590 600
EYGSPLDMTS ATEEMLTSFP PLQELLTHLA KPFISLETYV PTTVVRYLTA
610 620 630 640 650
GNNPRNLQPV SVEVVLLATD ICSFTPLSEK CSLTEVWTIC KTIFVAFIRA
660 670 680 690 700
IFNEGGEVIK LIGDCVTAYF PPTGADKAVH ACQEIVTFCA QLGDAFHDVL
710 720 730 740 750
DCRSVVACGV GLDFGQVIMA QCGSLGMTEF VVAGEVSARV MEVVALTREA
760 770 780 790 800
GRAIVITEPL PDRLAPKLRD TGIIPCQEGV DGVPCYGNLG PEWELDVATI
810 820 830 840 850
KKNIYGFHDA RALAAMKKVD VGTNAPGRGA PAGGIPSSPK VRPPGRTNSV
860 870 880 890 900
SSYTPDPNEA LDPPMAESVF LDMCHQRGDT ANNSIAVKLR QAANDDRLDL
910 920 930 940 950
GRMLQGPHEL MPVMQAIKHL TNLRMLNMSD NFVVDNNVGE LVESCIPMRS
960 970 980 990 1000
LQVLDLSNNP GLTKVIALKR LIKHNTQVRE FLLNGTRIAP TEQRKLQSSM
1010
NVNRLCASTD LKGSHKYEH
Length:1,019
Mass (Da):112,093
Last modified:January 10, 2006 - v1
Checksum:iEFC2B34B7744A492
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181335 mRNA Translation: CAJ57394.1

Similar proteinsi

Entry informationi

Entry nameiPALFB_EUGGR
AccessioniPrimary (citable) accession number: P84737
Secondary accession number(s): Q2P9N0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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