UniProtKB - P84388 (PLYB1_POLPI)
Protein
Polybine-1
Gene
N/A
Organism
Polybia paulista (Neotropical social wasp) (Swarm-founding polistine wasp)
Status
Functioni
Venom component which lacks hemolytic or antibiotic properties, but produces an inflammatory response via mast cell degranulation and produces a chemotactic effect on leukocytes.1 Publication
GO - Molecular functioni
- toxin activity Source: UniProtKB-KW
GO - Biological processi
- chemotaxis Source: UniProtKB
- mast cell degranulation Source: UniProtKB-KW
- positive regulation of mast cell degranulation Source: UniProtKB
Keywordsi
Molecular function | Toxin |
Biological process | Chemotaxis, Mast cell degranulation |
Names & Taxonomyi
Protein namesi | Recommended name: Polybine-1Alternative name(s): Polybine-I |
Organismi | Polybia paulista (Neotropical social wasp) (Swarm-founding polistine wasp) |
Taxonomic identifieri | 291283 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Hymenoptera › Apocrita › Aculeata › Vespoidea › Vespidae › Polistinae › Epiponini › Polybia |
Subcellular locationi
Extracellular region or secreted
- Secreted 1 Publication
Extracellular region or secreted
- extracellular region Source: UniProtKB
Lysosome
- mast cell granule Source: GOC
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
PeptideiPRO_0000044534 | 1 – 14 | Polybine-1Add BLAST | 14 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylserine1 Publication | 1 |
Keywords - PTMi
AcetylationPTM databases
iPTMneti | P84388 |
Expressioni
Tissue specificityi
Expressed by the venom gland.1 Publication
i Sequence
Sequence statusi: Complete.
Mass spectrometryi
Molecular mass is 1610.18±0.29 Da from positions 1 - 14. Determined by ESI. Acetylated and with addition of a proton.1 Publication
Cross-referencesi
3D structure databases
ModBasei | Search... |
MobiDBi | Search... |
PTM databases
iPTMneti | P84388 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Family and domain databases
ProtoNeti | Search... |
Entry informationi
Entry namei | PLYB1_POLPI | |
Accessioni | P84388Primary (citable) accession number: P84388 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 15, 2005 |
Last sequence update: | February 15, 2005 | |
Last modified: | November 22, 2017 | |
This is version 25 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Animal Toxin Annotation Program |