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Protein

Mexicain

Gene
N/A
Organism
Jacaratia mexicana (Wild papaya) (Pileus mexicanus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cysteine protease.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei25PROSITE-ProRule annotation1 Publication1
Active sitei159PROSITE-ProRule annotation1 Publication1
Active sitei175PROSITE-ProRule annotation1 Publication1

GO - Molecular functioni

  • cysteine-type peptidase activity Source: UniProtKB

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease

Names & Taxonomyi

Protein namesi
Recommended name:
Mexicain (EC:3.4.22.-)
OrganismiJacaratia mexicana (Wild papaya) (Pileus mexicanus)
Taxonomic identifieri309130 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesCaricaceaeJacaratia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000505561 – 214MexicainAdd BLAST214

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi22 ↔ 63Combined sources1 Publication
Disulfide bondi56 ↔ 95Combined sources1 Publication
Disulfide bondi153 ↔ 200Combined sources1 Publication

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed in latex.

Structurei

Secondary structure

1214
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP84346
SMRiP84346
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP84346

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Family and domain databases

CDDicd02248 Peptidase_C1A, 1 hit
InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR039417 Peptidase_C1A_papain-like
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00645 Pept_C1, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

P84346-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
YPESIDWREK GAVTPVKNQN PCGSCWAFST VATIEGINKI ITGQLISLSE
60 70 80 90 100
QELLDCEYRS HGCDGGYQTP SLQYVVDNGV HTEREYPYEK KQGRCRAKDK
110 120 130 140 150
KGPKVYITGY KYVPANDEIS LIQAIANQPV SVVTDSRGRG FQFYKGGIYE
160 170 180 190 200
GPCGTNTDHA VTAVGYGKTY LLLKNSWGPN WGEKGYIRIK RASGRSKGTC
210
GVYTSSFFPI KGYR
Length:214
Mass (Da):23,765
Last modified:February 15, 2005 - v1
Checksum:i2E79A1C58DF9A12F
GO

Similar proteinsi

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BDZX-ray2.10A/B/C/D1-214[»]
ProteinModelPortaliP84346
SMRiP84346
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP84346

Family and domain databases

CDDicd02248 Peptidase_C1A, 1 hit
InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR039417 Peptidase_C1A_papain-like
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00645 Pept_C1, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMEX1_JACME
AccessioniPrimary (citable) accession number: P84346
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: September 12, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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