UniProtKB - P84100 (RL19_RAT)
Protein
60S ribosomal protein L19
Gene
Rpl19
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- 5.8S rRNA binding Source: RGD
- large ribosomal subunit rRNA binding Source: RGD
- RNA binding Source: GO_Central
- structural constituent of ribosome Source: RGD
GO - Biological processi
- cytoplasmic translation Source: RGD
- liver regeneration Source: RGD
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-RNO-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-RNO-1799339, SRP-dependent cotranslational protein targeting to membrane R-RNO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-RNO-72689, Formation of a pool of free 40S subunits R-RNO-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-RNO-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-RNO-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L19 |
Gene namesi | Name:Rpl19 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 621183, Rpl19 |
Subcellular locationi
Cytosol
- cytosolic large ribosomal subunit Source: RGD
Other locations
- polysomal ribosome Source: RGD
- synapse Source: RGD
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000131172 | 1 – 196 | 60S ribosomal protein L19Add BLAST | 196 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 5 | CitrullineBy similarity | 1 | |
Modified residuei | 13 | PhosphoserineBy similarity | 1 | |
Modified residuei | 16 | CitrullineBy similarity | 1 | |
Modified residuei | 38 | CitrullineBy similarity | 1 | |
Modified residuei | 164 | PhosphoserineBy similarity | 1 | |
Cross-linki | 181 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity | ||
Modified residuei | 187 | PhosphothreonineBy similarity | 1 |
Post-translational modificationi
Citrullinated by PADI4.By similarity
Keywords - PTMi
Citrullination, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | P84100 |
PaxDbi | P84100 |
PRIDEi | P84100 |
PTM databases
iPTMneti | P84100 |
PhosphoSitePlusi | P84100 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000004741, Expressed in thymus and 20 other tissues |
Genevisiblei | P84100, RN |
Interactioni
Protein-protein interaction databases
BioGRIDi | 249639, 2 interactors |
IntActi | P84100, 4 interactors |
STRINGi | 10116.ENSRNOP00000006359 |
Family & Domainsi
Sequence similaritiesi
Belongs to the eukaryotic ribosomal protein eL19 family.Curated
Phylogenomic databases
eggNOGi | KOG1696, Eukaryota |
GeneTreei | ENSGT00390000012628 |
HOGENOMi | CLU_083919_0_1_1 |
InParanoidi | P84100 |
OMAi | NRVWIDP |
OrthoDBi | 1437042at2759 |
PhylomeDBi | P84100 |
TreeFami | TF313598 |
Family and domain databases
CDDi | cd01417, Ribosomal_L19e_E, 1 hit |
Gene3Di | 1.10.1650.10, 1 hit |
HAMAPi | MF_01475, Ribosomal_L19e, 1 hit |
InterProi | View protein in InterPro IPR035970, 60S_ribosomal_L19/L19e_sf IPR000196, Ribosomal_L19/L19e IPR023638, Ribosomal_L19/L19e_CS IPR015972, Ribosomal_L19/L19e_dom1 IPR033935, Ribosomal_L19_euka IPR039547, RPL19 |
PANTHERi | PTHR10722, PTHR10722, 1 hit |
Pfami | View protein in Pfam PF01280, Ribosomal_L19e, 1 hit |
SMARTi | View protein in SMART SM01416, Ribosomal_L19e, 1 hit |
SUPFAMi | SSF48140, SSF48140, 1 hit |
PROSITEi | View protein in PROSITE PS00526, RIBOSOMAL_L19E, 1 hit |
i Sequence
Sequence statusi: Complete.
P84100-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI
60 70 80 90 100
IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR
110 120 130 140 150
ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA
160 170 180 190
RKKLLADQAE ARRSKTKEAR KRREERLQAK KEEIIKTLSK EEETKK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J02650 mRNA Translation: AAA42071.1 X82202 Genomic DNA Translation: CAA57685.1 BC058135 mRNA Translation: AAH58135.1 |
PIRi | A26710, R5RT19 |
RefSeqi | NP_112365.1, NM_031103.1 |
Genome annotation databases
Ensembli | ENSRNOT00000006359; ENSRNOP00000006359; ENSRNOG00000004741 |
GeneIDi | 81767 |
KEGGi | rno:81767 |
UCSCi | RGD:621183, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J02650 mRNA Translation: AAA42071.1 X82202 Genomic DNA Translation: CAA57685.1 BC058135 mRNA Translation: AAH58135.1 |
PIRi | A26710, R5RT19 |
RefSeqi | NP_112365.1, NM_031103.1 |
3D structure databases
SMRi | P84100 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 249639, 2 interactors |
IntActi | P84100, 4 interactors |
STRINGi | 10116.ENSRNOP00000006359 |
PTM databases
iPTMneti | P84100 |
PhosphoSitePlusi | P84100 |
Proteomic databases
jPOSTi | P84100 |
PaxDbi | P84100 |
PRIDEi | P84100 |
Genome annotation databases
Ensembli | ENSRNOT00000006359; ENSRNOP00000006359; ENSRNOG00000004741 |
GeneIDi | 81767 |
KEGGi | rno:81767 |
UCSCi | RGD:621183, rat |
Organism-specific databases
CTDi | 6143 |
RGDi | 621183, Rpl19 |
Phylogenomic databases
eggNOGi | KOG1696, Eukaryota |
GeneTreei | ENSGT00390000012628 |
HOGENOMi | CLU_083919_0_1_1 |
InParanoidi | P84100 |
OMAi | NRVWIDP |
OrthoDBi | 1437042at2759 |
PhylomeDBi | P84100 |
TreeFami | TF313598 |
Enzyme and pathway databases
Reactomei | R-RNO-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-RNO-1799339, SRP-dependent cotranslational protein targeting to membrane R-RNO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-RNO-72689, Formation of a pool of free 40S subunits R-RNO-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-RNO-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-RNO-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Miscellaneous databases
PROi | PR:P84100 |
Gene expression databases
Bgeei | ENSRNOG00000004741, Expressed in thymus and 20 other tissues |
Genevisiblei | P84100, RN |
Family and domain databases
CDDi | cd01417, Ribosomal_L19e_E, 1 hit |
Gene3Di | 1.10.1650.10, 1 hit |
HAMAPi | MF_01475, Ribosomal_L19e, 1 hit |
InterProi | View protein in InterPro IPR035970, 60S_ribosomal_L19/L19e_sf IPR000196, Ribosomal_L19/L19e IPR023638, Ribosomal_L19/L19e_CS IPR015972, Ribosomal_L19/L19e_dom1 IPR033935, Ribosomal_L19_euka IPR039547, RPL19 |
PANTHERi | PTHR10722, PTHR10722, 1 hit |
Pfami | View protein in Pfam PF01280, Ribosomal_L19e, 1 hit |
SMARTi | View protein in SMART SM01416, Ribosomal_L19e, 1 hit |
SUPFAMi | SSF48140, SSF48140, 1 hit |
PROSITEi | View protein in PROSITE PS00526, RIBOSOMAL_L19E, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL19_RAT | |
Accessioni | P84100Primary (citable) accession number: P84100 Secondary accession number(s): P14118, P22908 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 16, 2004 |
Last sequence update: | August 16, 2004 | |
Last modified: | December 2, 2020 | |
This is version 119 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries