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Protein

60S ribosomal protein L19

Gene

Rpl19

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L19
Gene namesi
Name:Rpl19
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:98020 Rpl19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001311711 – 19660S ribosomal protein L19Add BLAST196

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei5Citrulline1 Publication1
Modified residuei13PhosphoserineBy similarity1
Modified residuei16Citrulline1 Publication1
Modified residuei38Citrulline1 Publication1
Modified residuei164PhosphoserineBy similarity1
Cross-linki181Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity
Modified residuei187PhosphothreonineBy similarity1

Post-translational modificationi

Citrullinated by PADI4.1 Publication

Keywords - PTMi

Citrullination, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiP84099
PaxDbiP84099
PRIDEiP84099
TopDownProteomicsiP84099

PTM databases

iPTMnetiP84099
PhosphoSitePlusiP84099
SwissPalmiP84099

Expressioni

Gene expression databases

BgeeiENSMUSG00000017404
CleanExiMM_RPL19
ExpressionAtlasiP84099 baseline and differential
GenevisibleiP84099 MM

Interactioni

Protein-protein interaction databases

BioGridi202969, 3 interactors
CORUMiP84099
IntActiP84099, 7 interactors
MINTiP84099
STRINGi10090.ENSMUSP00000017548

Structurei

3D structure databases

ProteinModelPortaliP84099
SMRiP84099
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP84099

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1696 Eukaryota
COG2147 LUCA
GeneTreeiENSGT00390000012628
HOGENOMiHOG000231277
HOVERGENiHBG056059
InParanoidiP84099
KOiK02885
OMAiNRVWIDP
OrthoDBiEOG091G0MKY
PhylomeDBiP84099
TreeFamiTF313598

Family and domain databases

CDDicd01417 Ribosomal_L19e_E, 1 hit
Gene3Di1.10.1650.10, 1 hit
HAMAPiMF_01475 Ribosomal_L19e, 1 hit
InterProiView protein in InterPro
IPR035970 60S_ribosomal_L19/L19e_sf
IPR000196 Ribosomal_L19/L19e
IPR023638 Ribosomal_L19/L19e_CS
IPR015972 Ribosomal_L19/L19e_dom1
IPR033935 Ribosomal_L19_euka
PfamiView protein in Pfam
PF01280 Ribosomal_L19e, 1 hit
SMARTiView protein in SMART
SM01416 Ribosomal_L19e, 1 hit
SUPFAMiSSF48140 SSF48140, 1 hit
PROSITEiView protein in PROSITE
PS00526 RIBOSOMAL_L19E, 1 hit

Sequencei

Sequence statusi: Complete.

P84099-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI
60 70 80 90 100
IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR
110 120 130 140 150
ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA
160 170 180 190
RKKLLADQAE ARRSKTKEAR KRREERLQAK KEEIIKTLSK EEETKK
Length:196
Mass (Da):23,466
Last modified:August 16, 2004 - v1
Checksum:i4AF506393E526216
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti179A → S in AAB48630 (PubMed:1702292).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M62952 mRNA Translation: AAB48630.1
AK010440 mRNA Translation: BAB26941.1
BC010710 mRNA Translation: AAH10710.1
BC083131 mRNA Translation: AAH83131.1
CCDSiCCDS25337.1
PIRiA36554
RefSeqiNP_033104.2, NM_009078.2
UniGeneiMm.10247

Genome annotation databases

EnsembliENSMUST00000017548; ENSMUSP00000017548; ENSMUSG00000017404
GeneIDi19921
KEGGimmu:19921
UCSCiuc007lfj.2 mouse

Similar proteinsi

Entry informationi

Entry nameiRL19_MOUSE
AccessioniPrimary (citable) accession number: P84099
Secondary accession number(s): P14118, P22908
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: June 20, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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