Ap2m1

Functionⁱ

Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 mu subunit binds to transmembrane cargo proteins; it recognizes the Y-X-X-Phi motifs. The surface region interacting with to the Y-X-X-Phi motif is inaccessible in cytosolic AP-2, but becomes accessible through a conformational change following phosphorylation of AP-2 mu subunit at 'Tyr-156' in membrane-associated AP-2. The membrane-specific phosphorylation event appears to involve assembled clathrin which activates the AP-2 mu kinase AAK1 (By similarity). Plays a role in endocytosis of frizzled family members upon Wnt signaling (By similarity).By similarity2 Publications

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	341	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	343	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	345	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	354	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	356	Phosphatidylinositol lipid headgroupBy similarity	1

GO - Molecular functionⁱ

cargo receptor activity
Source: SynGO
Inferred from direct assayⁱ
- 24217640
disordered domain specific binding
Source: CAFA
Inferred from direct assayⁱ
- 18321067
ion channel binding Source: MGI
lipid binding Source: UniProtKB-KW
low-density lipoprotein particle receptor binding Source: MGI
signal sequence binding Source: MGI

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

intracellular protein transport
Source: MGI
Traceable author statementⁱ
- 9714600
negative regulation of protein localization to plasma membrane Source: MGI
positive regulation of receptor internalization Source: MGI
positive regulation of synaptic vesicle endocytosis Source: MGI
postsynaptic neurotransmitter receptor internalization
Source: SynGO
Inferred from direct assayⁱ
- 24217640
protein-containing complex assembly Source: MGI
receptor internalization Source: MGI
regulation of vesicle size Source: MGI
synaptic vesicle endocytosis Source: MGI
vesicle budding from membrane Source: MGI
vesicle-mediated transport
Source: MGI
Traceable author statementⁱ
- 9714600
vesicle-mediated transport in synapse Source: MGI

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Endocytosis, Protein transport, Transport
Ligand	Lipid-binding

Enzyme and pathway databases

Reactomeⁱ	R-MMU-177504 Retrograde neurotrophin signalling R-MMU-190873 Gap junction degradation R-MMU-196025 Formation of annular gap junctions R-MMU-2132295 MHC class II antigen presentation R-MMU-416993 Trafficking of GluR2-containing AMPA receptors R-MMU-437239 Recycling pathway of L1 R-MMU-5099900 WNT5A-dependent internalization of FZD4 R-MMU-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis R-MMU-8856828 Clathrin-mediated endocytosis R-MMU-8866427 VLDLR internalisation and degradation R-MMU-8964038 LDL clearance

Reactomeⁱ

R-MMU-177504 Retrograde neurotrophin signalling
R-MMU-190873 Gap junction degradation
R-MMU-196025 Formation of annular gap junctions
R-MMU-2132295 MHC class II antigen presentation
R-MMU-416993 Trafficking of GluR2-containing AMPA receptors
R-MMU-437239 Recycling pathway of L1
R-MMU-5099900 WNT5A-dependent internalization of FZD4
R-MMU-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2
R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828 Clathrin-mediated endocytosis
R-MMU-8866427 VLDLR internalisation and degradation
R-MMU-8964038 LDL clearance

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: AP-2 complex subunit mu Alternative name(s): AP-2 mu chain Adaptor protein complex AP-2 subunit mu Adaptor-related protein complex 2 subunit mu Clathrin assembly protein complex 2 mu medium chain Clathrin coat assembly protein AP50 Clathrin coat-associated protein AP50 Mu2-adaptin Plasma membrane adaptor AP-2 50 kDa protein
Gene namesⁱ	Name:Ap2m1 Synonyms:Clapm1
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 16

Organism-specific databases

MGIⁱ	MGI:1298405 Ap2m1

Keywords - Cellular componentⁱ

Cell membrane, Coated pit, Membrane

Pathology & Biotechⁱ

Disruption phenotypeⁱ

Embryonic lethal before day 3.5 postcoitus (E3.5).1 Publication

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000193775	1 – 435	AP-2 complex subunit muAdd BLAST		435

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	45	PhosphoserineBy similarity		1
Modified residueⁱ	156	PhosphothreonineCombined sources		1

Post-translational modificationⁱ

Phosphorylated.By similarity

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	P84091
PaxDbⁱ	P84091
PeptideAtlas More...PeptideAtlasⁱ	P84091
PRIDEⁱ	P84091

PTM databases

iPTMnetⁱ	P84091
PhosphoSitePlusⁱ	P84091
SwissPalmⁱ	P84091

Expressionⁱ

Tissue specificityⁱ

Detected in spleen.

Gene expression databases

Bgeeⁱ	ENSMUSG00000022841 Expressed in 88 organ(s), highest expression level in Ammon's horn
CleanExⁱ	MM_AP2M1
ExpressionAtlasⁱ	P84091 baseline and differential
Genevisibleⁱ	P84091 MM

Interactionⁱ

Subunit structureⁱ

Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1) (By similarity). Interacts with ATP6V1H and MEGF10 (By similarity). Interacts with EGFR and TTGN1 (By similarity). Interacts with F2R (By similarity). Interacts with PIP5K1C isoform 1; tyrosine phosphorylation of PIP5K1C weakens the interaction. Does not interact with PIP5K1C isoform 3 (PubMed:16707488). Interacts with KIAA0319; required for clathrin-mediated endocytosis of KIAA0319 (By similarity). Interacts with DVL2 (via DEP domain) (By similarity). Interacts with KCNQ1; mediates estrogen-induced internalization via clathrin-coated vesicles (By similarity). Interacts with P2RX4 (via internalization motif) (By similarity).By similarity1 Publication

GO - Molecular functionⁱ

disordered domain specific binding
Source: CAFA
Inferred from direct assayⁱ
- 18321067
ion channel binding Source: MGI
low-density lipoprotein particle receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	198131, 8 interactors
IntActⁱ	P84091, 10 interactors
Molecular INTeraction database More...MINTⁱ	P84091
STRINGⁱ	10090.ENSMUSP00000007216

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P84091
SMRⁱ	P84091
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	170 – 434	MHDPROSITE-ProRule annotationAdd BLAST		265

Sequence similaritiesⁱ

Belongs to the adaptor complexes medium subunit family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0937 Eukaryota ENOG410XPFS LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000062779
HOGENOMⁱ	HOG000173246
HOVERGENⁱ	HBG050516
InParanoidⁱ	P84091
KEGG Orthology (KO) More...KOⁱ	K11826
OMAⁱ	SIKWVRY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G06XI
PhylomeDBⁱ	P84091
TreeFamⁱ	TF300722

Family and domain databases

InterProⁱ	View protein in InterPro IPR036168 AP2_Mu_C_sf IPR022775 AP_mu_sigma_su IPR001392 Clathrin_mu IPR018240 Clathrin_mu_CS IPR011012 Longin-like_dom_sf IPR028565 MHD
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00928 Adap_comp_sub, 1 hit PF01217 Clat_adaptor_s, 1 hit
PIRSFⁱ	PIRSF005992 Clathrin_mu, 1 hit
PRINTSⁱ	PR00314 CLATHRINADPT
SUPFAMⁱ	SSF49447 SSF49447, 1 hit SSF64356 SSF64356, 1 hit
PROSITEⁱ	View protein in PROSITE PS00990 CLAT_ADAPTOR_M_1, 1 hit PS00991 CLAT_ADAPTOR_M_2, 1 hit PS51072 MHD, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show all Align All

P84091-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MIGGLFIYNH KGEVLISRVY RDDIGRNAVD AFRVNVIHAR QQVRSPVTNI 
        60         70         80         90        100
ARTSFFHVKR SNIWLAAVTK QNVNAAMVFE FLYKMCDVMA AYFGKISEEN 
       110        120        130        140        150
IKNNFVLIYE LLDEILDFGY PQNSETGALK TFITQQGIKS QHQTKEEQSQ 
       160        170        180        190        200
ITSQVTGQIG WRREGIKYRR NELFLDVLES VNLLMSPQGQ VLSAHVSGRV 
       210        220        230        240        250
VMKSYLSGMP ECKFGMNDKI VIEKQGKGTA DETSKSGKQS IAIDDCTFHQ 
       260        270        280        290        300
CVRLSKFDSE RSISFIPPDG EFELMRYRTT KDIILPFRVI PLVREVGRTK 
       310        320        330        340        350
LEVKVVIKSN FKPSLLAQKI EVRIPTPLNT SGVQVICMKG KAKYKASENA 
       360        370        380        390        400
IVWKIKRMAG MKESQISAEI ELLPTNDKKK WARPPISMNF EVPFAPSGLK 
       410        420        430 
VRYLKVFEPK LNYSDHDVIK WVRYIGRSGI YETRC

Length:435

Mass (Da):49,655

Last modified:August 16, 2004 - v1

Checksum:ⁱ82803219BA279954

GO

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q3TWV4	Q3TWV4_MOUSE	AP-2 complex subunit mu AP-2 complex subunit mu (Adaptor protein complex AP-2, mu1, isoform CRA_a)	Ap2m1 mCG_128452	433	Annotation score:
A0A338P6T4	A0A338P6T4_MOUSE	AP-2 complex subunit mu AP-2 complex subunit mu	Ap2m1	119	Annotation score:
A0A338P798	A0A338P798_MOUSE	AP-2 complex subunit mu AP-2 complex subunit mu	Ap2m1	82	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U27106 mRNA Translation: AAC53158.1 AF001923 AF001922 Genomic DNA Translation: AAC53583.1 BC056352 mRNA Translation: AAH56352.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS28048.1
PIRⁱ	I49327 JC6563
NCBI Reference Sequences More...RefSeqⁱ	NP_033809.1, NM_009679.3
UniGeneⁱ	Mm.18946

Genome annotation databases

Ensemblⁱ	ENSMUST00000007216; ENSMUSP00000007216; ENSMUSG00000022841
GeneIDⁱ	11773
KEGGⁱ	mmu:11773
UCSC genome browser More...UCSCⁱ	uc007ypy.2 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P84091	AP-2 complex subunit mu	)	HUMAN		435	UniRef100_Q96CW1
AP-2 complex subunit mu		BOVIN		435
AP-2 complex subunit mu		MACFA		435
AP-2 complex subunit mu	)	RAT		435
AP2M1 isoform 4		PANTR		435
+30

Protein	Similar proteins		Species	Score	Length	Source
P84091	AP-2 complex subunit mu	)	HUMAN		435	UniRef90_Q96CW1
AP-2 complex subunit mu		BOVIN		435
AP-2 complex subunit mu		MACFA		435
AP-2 complex subunit mu	)	RAT		435
AP-2 complex subunit mu-B		DANRE		436
+356

Protein	Similar proteins		Species	Score	Length	Source
P84091	AP-2 complex subunit mu	)	HUMAN		435	UniRef50_Q96CW1
AP-2 complex subunit mu		BOVIN		435
AP-2 complex subunit mu		MACFA		435
AP-2 complex subunit mu	)	RAT		435
AP-2 complex subunit mu-A		DANRE		436
+537

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U27106 mRNA Translation: AAC53158.1 AF001923 AF001922 Genomic DNA Translation: AAC53583.1 BC056352 mRNA Translation: AAH56352.1
CCDSⁱ	CCDS28048.1
PIRⁱ	I49327 JC6563
RefSeqⁱ	NP_033809.1, NM_009679.3
UniGeneⁱ	Mm.18946

3D structure databases

ProteinModelPortalⁱ	P84091
SMRⁱ	P84091
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	198131, 8 interactors
IntActⁱ	P84091, 10 interactors
MINTⁱ	P84091
STRINGⁱ	10090.ENSMUSP00000007216

PTM databases

iPTMnetⁱ	P84091
PhosphoSitePlusⁱ	P84091
SwissPalmⁱ	P84091

Proteomic databases

EPDⁱ	P84091
PaxDbⁱ	P84091
PeptideAtlasⁱ	P84091
PRIDEⁱ	P84091

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000007216; ENSMUSP00000007216; ENSMUSG00000022841
GeneIDⁱ	11773
KEGGⁱ	mmu:11773
UCSCⁱ	uc007ypy.2 mouse

Organism-specific databases

CTDⁱ	1173
MGIⁱ	MGI:1298405 Ap2m1

Phylogenomic databases

eggNOGⁱ	KOG0937 Eukaryota ENOG410XPFS LUCA
GeneTreeⁱ	ENSGT00530000062779
HOGENOMⁱ	HOG000173246
HOVERGENⁱ	HBG050516
InParanoidⁱ	P84091
KOⁱ	K11826
OMAⁱ	SIKWVRY
OrthoDBⁱ	EOG091G06XI
PhylomeDBⁱ	P84091
TreeFamⁱ	TF300722

Enzyme and pathway databases

Reactomeⁱ	R-MMU-177504 Retrograde neurotrophin signalling R-MMU-190873 Gap junction degradation R-MMU-196025 Formation of annular gap junctions R-MMU-2132295 MHC class II antigen presentation R-MMU-416993 Trafficking of GluR2-containing AMPA receptors R-MMU-437239 Recycling pathway of L1 R-MMU-5099900 WNT5A-dependent internalization of FZD4 R-MMU-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis R-MMU-8856828 Clathrin-mediated endocytosis R-MMU-8866427 VLDLR internalisation and degradation R-MMU-8964038 LDL clearance

Reactomeⁱ

R-MMU-177504 Retrograde neurotrophin signalling
R-MMU-190873 Gap junction degradation
R-MMU-196025 Formation of annular gap junctions
R-MMU-2132295 MHC class II antigen presentation
R-MMU-416993 Trafficking of GluR2-containing AMPA receptors
R-MMU-437239 Recycling pathway of L1
R-MMU-5099900 WNT5A-dependent internalization of FZD4
R-MMU-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2
R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828 Clathrin-mediated endocytosis
R-MMU-8866427 VLDLR internalisation and degradation
R-MMU-8964038 LDL clearance

Miscellaneous databases

ChiTaRSⁱ	Ap2m1 mouse
Protein Ontology More...PROⁱ	PR:P84091
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000022841 Expressed in 88 organ(s), highest expression level in Ammon's horn
CleanExⁱ	MM_AP2M1
ExpressionAtlasⁱ	P84091 baseline and differential
Genevisibleⁱ	P84091 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR036168 AP2_Mu_C_sf IPR022775 AP_mu_sigma_su IPR001392 Clathrin_mu IPR018240 Clathrin_mu_CS IPR011012 Longin-like_dom_sf IPR028565 MHD
Pfamⁱ	View protein in Pfam PF00928 Adap_comp_sub, 1 hit PF01217 Clat_adaptor_s, 1 hit
PIRSFⁱ	PIRSF005992 Clathrin_mu, 1 hit
PRINTSⁱ	PR00314 CLATHRINADPT
SUPFAMⁱ	SSF49447 SSF49447, 1 hit SSF64356 SSF64356, 1 hit
PROSITEⁱ	View protein in PROSITE PS00990 CLAT_ADAPTOR_M_1, 1 hit PS00991 CLAT_ADAPTOR_M_2, 1 hit PS51072 MHD, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	AP2M1_MOUSE
Accessionⁱ	P84091Primary (citable) accession number: P84091 Secondary accession number(s): P20172, P53679
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
	Last sequence update:	August 16, 2004
	Last modified:	November 7, 2018
	This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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UniRef

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Supporting data

UniProtKB - P84091 (AP2M1_MOUSE)

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AP-2 complex subunit mu

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Other locations

Mitochondrion

Plasma Membrane

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ