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Protein

Homeotic protein ultrabithorax

Gene

Ubx

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds the consensus region 5'-TTAAT[GT][GA]-3'. This homeotic protein controls development of the cells in the posterior thoracic and first abdominal segments. It activates the synthesis of the decapentaplegic (DPP) growth factor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi295 – 354HomeoboxPROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P83949

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Homeotic protein ultrabithorax
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ubx
ORF Names:CG10388
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0003944 Ubx

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002002681 – 389Homeotic protein ultrabithoraxAdd BLAST389

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei170Phosphothreonine1 Publication1
Modified residuei174Phosphoserine1 Publication1
Modified residuei177Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P83949

PRoteomics IDEntifications database

More...
PRIDEi
P83949

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P83949

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In the embryo, expression is seen in the epidermis, somatic and visceral mesoderm, and the peripheral and central nervous system.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0003944 Expressed in 19 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P83949 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P83949 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
67078, 111 interactors

Database of interacting proteins

More...
DIPi
DIP-33048N

Protein interaction database and analysis system

More...
IntActi
P83949, 28 interactors

Molecular INTeraction database

More...
MINTi
P83949

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0082793

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1389
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B8IX-ray2.40A233-356[»]
4CYCX-ray2.36A233-367[»]
4UUSX-ray2.55A/E292-367[»]
4UUTX-ray2.80A233-367[»]

Database of protein disorder

More...
DisProti
DP00623

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P83949

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P83949

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P83949

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi239 – 244Antp-type hexapeptide6
Motifi368 – 383QAAdd BLAST16

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi33 – 39Poly-Ala7
Compositional biasi111 – 129Poly-GlyAdd BLAST19
Compositional biasi322 – 325Poly-Arg4

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The QA motif is able to mediate transcriptional repression.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Antp homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG0489 Eukaryota
ENOG410ZTBY LUCA

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P83949

KEGG Orthology (KO)

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KOi
K09311

Identification of Orthologs from Complete Genome Data

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OMAi
YGSHHHQ

Database for complete collections of gene phylogenies

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PhylomeDBi
P83949

Family and domain databases

Conserved Domains Database

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CDDi
cd00086 homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057 Homeobox-like_sf
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa

Pfam protein domain database

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Pfami
View protein in Pfam
PF00046 Homeodomain, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00024 HOMEOBOX

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00389 HOX, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF46689 SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform IB (identifier: P83949-1) [UniParc]FASTAAdd to basket
Also known as: A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNSYFEQASG FYGHPHQATG MAMGSGGHHD QTASAAAAAY RGFPLSLGMS
60 70 80 90 100
PYANHHLQRT TQDSPYDASI TAACNKIYGD GAGAYKQDCL NIKADAVNGY
110 120 130 140 150
KDIWNTGGSN GGGGGGGGGG GGGAGGTGGA GNANGGNAAN ANGQNNPAGG
160 170 180 190 200
MPVRPSACTP DSRVGGYLDT SGGSPVSHRG GSAGGNVSVS GGNGNAGGVQ
210 220 230 240 250
SGVGVAGAGT AWNANCTISG AAAQTAAASS LHQASNHTFY PWMAIAGECP
260 270 280 290 300
EDPTKSKIRS DLTQYGGIST DMGKRYSESL AGSLLPDWLG TNGLRRRGRQ
310 320 330 340 350
TYTRYQTLEL EKEFHTNHYL TRRRRIEMAH ALCLTERQIK IWFQNRRMKL
360 370 380
KKEIQAIKEL NEQEKQAQAQ KAAAAAAAAA AVQGGHLDQ
Length:389
Mass (Da):40,040
Last modified:June 7, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD452E8FFE55D8F53
GO
Isoform IA (identifier: P83949-2) [UniParc] [UniParc]FASTAAdd to basket
Also known as: E

The sequence of this isoform differs from the canonical sequence as follows:
     248-256: Missing.

Show »
Length:380
Mass (Da):39,053
Checksum:iB8A8FE2B19724E28
GO
Isoform IIA (identifier: P83949-3) [UniParc] [UniParc]FASTAAdd to basket
Also known as: D

The sequence of this isoform differs from the canonical sequence as follows:
     248-273: Missing.

Show »
Length:363
Mass (Da):37,229
Checksum:i55DD2D46391F1FC6
GO
Isoform IIB (identifier: P83949-4) [UniParc] [UniParc]FASTAAdd to basket
Also known as: C

The sequence of this isoform differs from the canonical sequence as follows:
     258-274: Missing.

Show »
Length:372
Mass (Da):38,216
Checksum:iA58E24FA4415FD4C
GO
Isoform IVA (identifier: P83949-5) [UniParc] [UniParc]FASTAAdd to basket
Also known as: B

The sequence of this isoform differs from the canonical sequence as follows:
     248-290: Missing.

Show »
Length:346
Mass (Da):35,355
Checksum:i4D4610EC2BA13E05
GO
Isoform IVB (identifier: P83949-6) [UniParc] [UniParc]FASTAAdd to basket
Also known as: F

The sequence of this isoform differs from the canonical sequence as follows:
     257-290: Missing.

Show »
Length:355
Mass (Da):36,342
Checksum:i9C764B4C095711D7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti75N → Y in AAA84412 (PubMed:7667301).Curated1
Sequence conflicti75N → Y in AAA84411 (PubMed:7667301).Curated1
Sequence conflicti75N → Y in AAA84410 (PubMed:7667301).Curated1
Sequence conflicti75N → Y in AAA84409 (PubMed:7667301).Curated1
Sequence conflicti75N → Y in AAA84408 (PubMed:7667301).Curated1
Sequence conflicti330H → Y in AAA28615 (PubMed:6327065).Curated1
Sequence conflicti340K → E in AAA28615 (PubMed:6327065).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_002407248 – 290Missing in isoform IVA. 1 PublicationAdd BLAST43
Alternative sequenceiVSP_002406248 – 273Missing in isoform IIA. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_002405248 – 256Missing in isoform IA. 2 Publications9
Alternative sequenceiVSP_002409257 – 290Missing in isoform IVB. 1 PublicationAdd BLAST34
Alternative sequenceiVSP_002408258 – 274Missing in isoform IIB. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X05723
, X05724, X05725, X05727 Genomic DNA Translation: CAA29194.1
X76210 mRNA Translation: CAA53803.1
U31961 Genomic DNA Translation: AAA84412.1
U31961 Genomic DNA Translation: AAA84411.1
U31961 Genomic DNA Translation: AAA84410.1
U31961 Genomic DNA Translation: AAA84409.1
U31961 Genomic DNA Translation: AAA84408.1
AE014297 Genomic DNA Translation: AAF55355.2
AE014297 Genomic DNA Translation: AAF55356.1
AE014297 Genomic DNA Translation: AAN13717.1
AE014297 Genomic DNA Translation: AAN13718.1
AE014297 Genomic DNA Translation: AAN13719.1
AE014297 Genomic DNA Translation: AAS65158.1
BT010241 mRNA Translation: AAQ23559.1
K01963 Genomic DNA Translation: AAA29008.1 Sequence problems.
K01959 Genomic DNA Translation: AAA28615.1 Sequence problems.
X05427 Genomic DNA Translation: CAA29009.1

Protein sequence database of the Protein Information Resource

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PIRi
B27867
D26995

NCBI Reference Sequences

More...
RefSeqi
NP_536748.1, NM_080500.4 [P83949-5]
NP_536752.1, NM_080504.4 [P83949-1]
NP_732171.1, NM_169728.3 [P83949-3]
NP_732172.1, NM_169729.3 [P83949-2]
NP_732173.1, NM_169730.3 [P83949-4]
NP_996219.1, NM_206497.3 [P83949-6]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Dm.21668

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0083347; FBpp0082793; FBgn0003944 [P83949-1]
FBtr0083348; FBpp0082794; FBgn0003944 [P83949-5]
FBtr0083349; FBpp0082795; FBgn0003944 [P83949-4]
FBtr0083350; FBpp0082796; FBgn0003944 [P83949-3]
FBtr0083351; FBpp0082797; FBgn0003944 [P83949-2]
FBtr0083352; FBpp0089155; FBgn0003944 [P83949-6]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42034

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG10388

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05723
, X05724, X05725, X05727 Genomic DNA Translation: CAA29194.1
X76210 mRNA Translation: CAA53803.1
U31961 Genomic DNA Translation: AAA84412.1
U31961 Genomic DNA Translation: AAA84411.1
U31961 Genomic DNA Translation: AAA84410.1
U31961 Genomic DNA Translation: AAA84409.1
U31961 Genomic DNA Translation: AAA84408.1
AE014297 Genomic DNA Translation: AAF55355.2
AE014297 Genomic DNA Translation: AAF55356.1
AE014297 Genomic DNA Translation: AAN13717.1
AE014297 Genomic DNA Translation: AAN13718.1
AE014297 Genomic DNA Translation: AAN13719.1
AE014297 Genomic DNA Translation: AAS65158.1
BT010241 mRNA Translation: AAQ23559.1
K01963 Genomic DNA Translation: AAA29008.1 Sequence problems.
K01959 Genomic DNA Translation: AAA28615.1 Sequence problems.
X05427 Genomic DNA Translation: CAA29009.1
PIRiB27867
D26995
RefSeqiNP_536748.1, NM_080500.4 [P83949-5]
NP_536752.1, NM_080504.4 [P83949-1]
NP_732171.1, NM_169728.3 [P83949-3]
NP_732172.1, NM_169729.3 [P83949-2]
NP_732173.1, NM_169730.3 [P83949-4]
NP_996219.1, NM_206497.3 [P83949-6]
UniGeneiDm.21668

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B8IX-ray2.40A233-356[»]
4CYCX-ray2.36A233-367[»]
4UUSX-ray2.55A/E292-367[»]
4UUTX-ray2.80A233-367[»]
DisProtiDP00623
ProteinModelPortaliP83949
SMRiP83949
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi67078, 111 interactors
DIPiDIP-33048N
IntActiP83949, 28 interactors
MINTiP83949
STRINGi7227.FBpp0082793

PTM databases

iPTMnetiP83949

Proteomic databases

PaxDbiP83949
PRIDEiP83949

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0083347; FBpp0082793; FBgn0003944 [P83949-1]
FBtr0083348; FBpp0082794; FBgn0003944 [P83949-5]
FBtr0083349; FBpp0082795; FBgn0003944 [P83949-4]
FBtr0083350; FBpp0082796; FBgn0003944 [P83949-3]
FBtr0083351; FBpp0082797; FBgn0003944 [P83949-2]
FBtr0083352; FBpp0089155; FBgn0003944 [P83949-6]
GeneIDi42034
KEGGidme:Dmel_CG10388

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
42034
FlyBaseiFBgn0003944 Ubx

Phylogenomic databases

eggNOGiKOG0489 Eukaryota
ENOG410ZTBY LUCA
InParanoidiP83949
KOiK09311
OMAiYGSHHHQ
PhylomeDBiP83949

Enzyme and pathway databases

SignaLinkiP83949

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Ubx fly
EvolutionaryTraceiP83949

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
42034

Protein Ontology

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PROi
PR:P83949

Gene expression databases

BgeeiFBgn0003944 Expressed in 19 organ(s), highest expression level in embryo
ExpressionAtlasiP83949 baseline and differential
GenevisibleiP83949 DM

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeodomain, 1 hit
PRINTSiPR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBX_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P83949
Secondary accession number(s): P02834
, Q9TX83, Q9VER4, Q9VER5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: June 7, 2004
Last modified: January 16, 2019
This is version 158 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
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