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Protein

60S ribosomal protein L36a

Gene

Rpl36a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L36a
Alternative name(s):
60S ribosomal protein L44
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rpl36a
Synonyms:Rpl44
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 12, Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1201789 Rpl36a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001491201 – 10660S ribosomal protein L36aAdd BLAST106

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P83882

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P83882

PeptideAtlas

More...
PeptideAtlasi
P83882

PRoteomics IDEntifications database

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PRIDEi
P83882

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P83882

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P83882

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P83882

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P83882

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000049751 Expressed in 32 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P83882 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P83882 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
P83882, 1 interactor

Molecular INTeraction database

More...
MINTi
P83882

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000108837

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P83882

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P83882

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3464 Eukaryota
COG1631 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018085

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000224989

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG056127

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P83882

KEGG Orthology (KO)

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KOi
K02929

Identification of Orthologs from Complete Genome Data

More...
OMAi
YGGFPRP

Database of Orthologous Groups

More...
OrthoDBi
EOG091G12JU

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P83882

TreeFam database of animal gene trees

More...
TreeFami
TF300213

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000552 Ribosomal_L44e
IPR011332 Ribosomal_zn-bd

The PANTHER Classification System

More...
PANTHERi
PTHR10369 PTHR10369, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00935 Ribosomal_L44, 1 hit

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD002841 Ribosomal_L44e, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57829 SSF57829, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01172 RIBOSOMAL_L44E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P83882-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGKRR YDRKQSGYGG
60 70 80 90 100
QTKPIFRKKA KTTKKIVLRL ECVEPNCRSK RMLAIKRCKH FELGGDKKRK

GQVIQF
Length:106
Mass (Da):12,441
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE3308265D70BD26
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q131E9Q131_MOUSE
60S ribosomal protein L36a
Rpl36a
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U58105 Genomic DNA Translation: AAB47245.1
AK002540 mRNA Translation: BAB22175.1
AK003166 mRNA Translation: BAB22616.1
AK010629 mRNA Translation: BAB27075.1
AK012502 mRNA Translation: BAB28285.1
BC019810 mRNA Translation: AAH19810.1
BC027515 mRNA Translation: AAH27515.1
BC081439 mRNA Translation: AAH81439.1
BC081440 mRNA Translation: AAH81440.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS41123.1

NCBI Reference Sequences

More...
RefSeqi
NP_063918.1, NM_019865.5
NP_079865.1, NM_025589.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.286408
Mm.379115
Mm.491116

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000054544; ENSMUSP00000059766; ENSMUSG00000049751
ENSMUST00000110619; ENSMUSP00000106249; ENSMUSG00000049751
ENSMUST00000110620; ENSMUSP00000106250; ENSMUSG00000049751
ENSMUST00000113211; ENSMUSP00000108837; ENSMUSG00000079435

Database of genes from NCBI RefSeq genomes

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GeneIDi
19982
66483

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:19982
mmu:66483

UCSC genome browser

More...
UCSCi
uc007nrs.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U58105 Genomic DNA Translation: AAB47245.1
AK002540 mRNA Translation: BAB22175.1
AK003166 mRNA Translation: BAB22616.1
AK010629 mRNA Translation: BAB27075.1
AK012502 mRNA Translation: BAB28285.1
BC019810 mRNA Translation: AAH19810.1
BC027515 mRNA Translation: AAH27515.1
BC081439 mRNA Translation: AAH81439.1
BC081440 mRNA Translation: AAH81440.1
CCDSiCCDS41123.1
RefSeqiNP_063918.1, NM_019865.5
NP_079865.1, NM_025589.4
UniGeneiMm.286408
Mm.379115
Mm.491116

3D structure databases

ProteinModelPortaliP83882
SMRiP83882
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP83882, 1 interactor
MINTiP83882
STRINGi10090.ENSMUSP00000108837

PTM databases

iPTMnetiP83882
PhosphoSitePlusiP83882
SwissPalmiP83882

Proteomic databases

EPDiP83882
PaxDbiP83882
PeptideAtlasiP83882
PRIDEiP83882
TopDownProteomicsiP83882

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000054544; ENSMUSP00000059766; ENSMUSG00000049751
ENSMUST00000110619; ENSMUSP00000106249; ENSMUSG00000049751
ENSMUST00000110620; ENSMUSP00000106250; ENSMUSG00000049751
ENSMUST00000113211; ENSMUSP00000108837; ENSMUSG00000079435
GeneIDi19982
66483
KEGGimmu:19982
mmu:66483
UCSCiuc007nrs.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6166
6173
MGIiMGI:1201789 Rpl36a

Phylogenomic databases

eggNOGiKOG3464 Eukaryota
COG1631 LUCA
GeneTreeiENSGT00390000018085
HOGENOMiHOG000224989
HOVERGENiHBG056127
InParanoidiP83882
KOiK02929
OMAiYGGFPRP
OrthoDBiEOG091G12JU
PhylomeDBiP83882
TreeFamiTF300213

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P83882

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000049751 Expressed in 32 organ(s), highest expression level in female gonad
ExpressionAtlasiP83882 baseline and differential
GenevisibleiP83882 MM

Family and domain databases

InterProiView protein in InterPro
IPR000552 Ribosomal_L44e
IPR011332 Ribosomal_zn-bd
PANTHERiPTHR10369 PTHR10369, 1 hit
PfamiView protein in Pfam
PF00935 Ribosomal_L44, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002841 Ribosomal_L44e, 1 hit
SUPFAMiSSF57829 SSF57829, 1 hit
PROSITEiView protein in PROSITE
PS01172 RIBOSOMAL_L44E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL36A_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P83882
Secondary accession number(s): P09896, P10661
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: January 23, 2007
Last modified: December 5, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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