Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 25 of 66  Show
  1. 1
    "WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain."
    O'Reilly M., Marshall E., Speirs H.J., Brown R.W.
    J. Am. Soc. Nephrol. 14:2447-2456(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 7), TISSUE SPECIFICITY, ALTERNATIVE SPLICING.
    Category: Expression, Sequences.
    Strain: C57BL/6J.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 14 other entries.

  2. 2
    "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
    Category: Sequences.
    Tissue: Embryonic tail.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 473 and mapped to 4 other entries.

  3. 3
    Category: Sequences.
    Strain: C57BL/6J.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 43064 other entries.

  4. 4
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 5), PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2/3).
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Embryo.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  5. 5
    "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-578.
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Embryo.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 10625 and mapped to 43846 other entries.

  6. 6
    Category: Subcellular Location, Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 and mapped to 21 other entries.

  7. 7
    "WNK kinases regulate thiazide-sensitive Na-Cl cotransport."
    Yang C.-L., Angell J., Mitchell R., Ellison D.H.
    J. Clin. Invest. 111:1039-1045(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 22 other entries.

  8. 8
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 and mapped to 8 other entries.

  9. 9
    "Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform."
    Subramanya A.R., Yang C.L., Zhu X., Ellison D.H.
    Am. J. Physiol. 290:F619-F624(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: ALTERNATIVE SPLICING.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 18 other entries.

  10. 10
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2027, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3197 other entries.

  11. 11
    "Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II."
    Shekarabi M., Girard N., Riviere J.B., Dion P., Houle M., Toulouse A., Lafreniere R.G., Vercauteren F., Hince P., Laganiere J., Rochefort D., Faivre L., Samuels M., Rouleau G.A.
    J. Clin. Invest. 118:2496-2505(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: ALTERNATIVE SPLICING (ISOFORMS 2 AND 3), TISSUE SPECIFICITY.
    Category: Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 24 other entries.

  12. 12
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-17; SER-2027; SER-2265 AND SER-2281, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 25326 other entries.

  13. 13
    "IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway."
    Yang D., Li Q., So I., Huang C.L., Ando H., Mizutani A., Seki G., Mikoshiba K., Thomas P.J., Muallem S.
    J. Clin. Invest. 121:956-965(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY, MUTAGENESIS OF ASP-368.
    Category: Function, Pathology & Biotech, Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5 and mapped to 77 other entries.

  14. 14
    "Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice."
    Park S., Shcheynikov N., Hong J.H., Zheng C., Suh S.H., Kawaai K., Ando H., Mizutani A., Abe T., Kiyonari H., Seki G., Yule D., Mikoshiba K., Muallem S.
    Gastroenterology 145:232-241(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5 and mapped to 19 other entries.

  15. 15
    "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H., Yamanaka I., Kiyosawa H., Yagi K., Tomaru Y., Hasegawa Y., Nogami A., Schonbach C., Gojobori T.
    Hayashizaki Y.
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2442092.

    This publication is cited by 16984 and mapped to 41260 other entries.

  16. 16
    Category: Sequences.
    Source: MGI:2442092.

    This publication is mapped to 18611 other entries.

  17. 17
    "WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia."
    Choate K.A., Kahle K.T., Wilson F.H., Nelson-Williams C., Lifton R.P.
    Proc. Natl. Acad. Sci. U.S.A. 100:663-668(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: findings suggest that WNK1 plays a general role in the regulation of epithelial Cl(-) flux [WNK1].
    Source: GeneRIF:232341.

    This publication is mapped to 5 other entries.

  18. 18
    "A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome."
    Hansen J., Floss T., Van Sloun P., Fuchtbauer E.M., Vauti F., Arnold H.H., Schnutgen F., Wurst W., von Melchner H., Ruiz P.
    Proc. Natl. Acad. Sci. U.S.A. 100:9918-9922(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2442092.

    This publication is mapped to 13831 other entries.

  19. 19
    Category: Pathology & Biotech.
    Annotation: Wnk1 heterozygous mice displayed a significant decrease in blood pressure. [GeneRIF:232341].
    Source: MGI:2442092, GeneRIF:232341.

    This publication is mapped to 39464 other entries.

  20. 20
    "GenePaint.org: an atlas of gene expression patterns in the mouse embryo."
    Visel A., Thaller C., Eichele G.
    Nucleic Acids Res. 32:D552-D556(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2442092.

    This publication is mapped to 13819 other entries.

  21. 21
    "WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding."
    Lee B.H., Min X., Heise C.J., Xu B.E., Chen S., Shu H., Luby-Phelps K., Goldsmith E.J., Cobb M.H.
    Mol. Cell 15:741-751(2004) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Source: MGI:2442092.

    This publication is mapped to 57 other entries.

  22. 22
    Category: Expression.
    Source: MGI:2442092.

    This publication is mapped to 919 other entries.

  23. 23
    "Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells."
    Jiang Z.Y., Zhou Q.L., Holik J., Patel S., Leszyk J., Coleman K., Chouinard M., Czech M.P.
    J. Biol. Chem. 280:21622-21628(2005) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: WNK1 is a physiologically relevant target of insulin signaling through PI3K and Akt/PKB and functions as a negative regulator of insulin-stimulated mitogenesis. [GeneRIF:232341].
    Source: MGI:2442092, GeneRIF:232341.

    This publication is mapped to 23 other entries.

  24. 24
    "BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system."
    Magdaleno S., Jensen P., Brumwell C.L., Seal A., Lehman K., Asbury A., Cheung T., Cornelius T., Batten D.M., Eden C., Norland S.M., Rice D.S., Dosooye N., Shakya S., Mehta P., Curran T.
    PLoS Biol. 4:e86-e86(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2442092.

    This publication is mapped to 20511 other entries.

  25. 25
    "Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved."
    Golbang A.P., Cope G., Hamad A., Murthy M., Liu C.H., Cuthbert A.W., O'shaughnessy K.M.
    Am. J. Physiol. Renal Physiol. 291:F1369-76(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: important differences in the mechanism by which WNK kinases affect expression of NCCT.
    Source: GeneRIF:232341.

    This publication is mapped to 12 other entries.

1 to 25 of 66  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again