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Entry version 106 (29 Sep 2021)
Sequence version 2 (16 Jun 2009)
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Protein

1,5-anhydro-D-fructose reductase

Gene

AKR1E2

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by p-chloromercuribenzoic acid and alkyliodines.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.44 mM for 1,5-anhydro-D-fructose1 Publication

pH dependencei

Optimum pH is 7.0.1 Publication

Temperature dependencei

Optimum temperature is 37 degrees Celsius.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei35NADPBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei40Proton donorBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei69Lowers pKa of active site TyrBy similarity1
Binding sitei102SubstrateBy similarity1
Binding sitei175NADPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi246 – 258NADPBy similarityAdd BLAST13

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
LigandNADP

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:MONOMER-17139

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
1,5-anhydro-D-fructose reductase (EC:1.1.1.2631 Publication)
Short name:
AF reductase
Alternative name(s):
Aldo-keto reductase family 1 member C-like protein 2
Short name:
Aldo-keto reductase family 1 member CL2
Aldo-keto reductase family 1 member E2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AKR1E2
Synonyms:AKR1CL2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10
  • UP000008227 Componenti: Chromosome 10

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:96003, AKR1E2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001246741 – 3011,5-anhydro-D-fructose reductaseAdd BLAST301

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P82125

PeptideAtlas

More...
PeptideAtlasi
P82125

PRoteomics IDEntifications database

More...
PRIDEi
P82125

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000026214, Expressed in adult mammalian kidney and 31 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P82125, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P82125, SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000011901

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P82125

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the aldo/keto reductase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1577, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153272

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023205_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P82125

Identification of Orthologs from Complete Genome Data

More...
OMAi
KLWPTDQ

Database of Orthologous Groups

More...
OrthoDBi
1016440at2759

TreeFam database of animal gene trees

More...
TreeFami
TF106492

Family and domain databases

Conserved Domains Database

More...
CDDi
cd19110, AKR_AKR1E1-2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.100, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020471, AKR
IPR044484, AKR1E2
IPR018170, Aldo/ket_reductase_CS
IPR023210, NADP_OxRdtase_dom
IPR036812, NADP_OxRdtase_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00248, Aldo_ket_red, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000097, AKR, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00069, ALDKETRDTASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51430, SSF51430, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00798, ALDOKETO_REDUCTASE_1, 1 hit
PS00062, ALDOKETO_REDUCTASE_2, 1 hit
PS00063, ALDOKETO_REDUCTASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform Long (identifier: P82125-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEKIPVLGLG TWQAAPGEVT EAVKVAIDTG YRHFDCAYLY HNENEVGVGI
60 70 80 90 100
QAKIDEGVVR REDLFIVSKL WCTCHKKSLV KSACTRSLKA LKLQYLDLYL
110 120 130 140 150
IHWPMGFKPG EVDLPVDRSG MIVASNTDFL DTWEAMEDLV IEGLVRAIGV
160 170 180 190 200
SNFNHEQLER LLNKPNLRVK PVTNQIECHP YLTQKKLISF CQSRNVSVTA
210 220 230 240 250
YRPLGGSSEG VPLLEDPVIQ TIAQKHGKSA AQILIRFQIQ RNVIVIPKSV
260 270 280 290 300
NPKRILENFQ VFDFELSEQD MTDLLGLDRN LRLSAFPIAE NHKDYPFKAE

Y
Length:301
Mass (Da):34,107
Last modified:June 16, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B7D0FDFD141ED2E
GO
Isoform Short (identifier: P82125-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     288-288: I → M
     289-301: Missing.

Note: Due to exon inclusion.Curated
Show »
Length:288
Mass (Da):32,532
Checksum:i41274E9FC8F1E1A7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286ZQQ7A0A286ZQQ7_PIG
1,5-anhydro-D-fructose reductase
AKR1E2
296Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5S6HCI3A0A5S6HCI3_PIG
1,5-anhydro-D-fructose reductase
AKR1E2
290Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_037445288I → M in isoform Short. 1 Publication1
Alternative sequenceiVSP_037446289 – 301Missing in isoform Short. 1 PublicationAdd BLAST13

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ474064 mRNA Translation: ABF18830.1
DB808243 mRNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001038033.2, NM_001044568.2 [P82125-1]
XP_013835805.1, XM_013980351.1 [P82125-1]
XP_013835806.1, XM_013980352.1 [P82125-1]
XP_013835811.1, XM_013980357.1
XP_013835812.1, XM_013980358.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000012204; ENSSSCP00000011891; ENSSSCG00000036941 [P82125-1]
ENSSSCT00000052191; ENSSSCP00000046702; ENSSSCG00000036941 [P82125-2]
ENSSSCT00005029791; ENSSSCP00005018130; ENSSSCG00005018482 [P82125-1]
ENSSSCT00005029824; ENSSSCP00005018154; ENSSSCG00005018482 [P82125-1]
ENSSSCT00005029849; ENSSSCP00005018168; ENSSSCG00005018482 [P82125-1]
ENSSSCT00025032851; ENSSSCP00025013710; ENSSSCG00025024226 [P82125-1]
ENSSSCT00035029808; ENSSSCP00035011546; ENSSSCG00035022798 [P82125-1]
ENSSSCT00045048830; ENSSSCP00045033959; ENSSSCG00045028552 [P82125-1]
ENSSSCT00055002173; ENSSSCP00055001633; ENSSSCG00055001205 [P82125-1]
ENSSSCT00060086891; ENSSSCP00060037590; ENSSSCG00060063649 [P82125-1]
ENSSSCT00065085447; ENSSSCP00065037345; ENSSSCG00065062289 [P82125-1]
ENSSSCT00065085458; ENSSSCP00065037352; ENSSSCG00065062289 [P82125-1]
ENSSSCT00070011622; ENSSSCP00070009575; ENSSSCG00070006087 [P82125-1]
ENSSSCT00070011628; ENSSSCP00070009581; ENSSSCG00070006087 [P82125-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
733633

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:733633

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ474064 mRNA Translation: ABF18830.1
DB808243 mRNA No translation available.
RefSeqiNP_001038033.2, NM_001044568.2 [P82125-1]
XP_013835805.1, XM_013980351.1 [P82125-1]
XP_013835806.1, XM_013980352.1 [P82125-1]
XP_013835811.1, XM_013980357.1
XP_013835812.1, XM_013980358.1

3D structure databases

SMRiP82125
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000011901

Proteomic databases

PaxDbiP82125
PeptideAtlasiP82125
PRIDEiP82125

Genome annotation databases

EnsembliENSSSCT00000012204; ENSSSCP00000011891; ENSSSCG00000036941 [P82125-1]
ENSSSCT00000052191; ENSSSCP00000046702; ENSSSCG00000036941 [P82125-2]
ENSSSCT00005029791; ENSSSCP00005018130; ENSSSCG00005018482 [P82125-1]
ENSSSCT00005029824; ENSSSCP00005018154; ENSSSCG00005018482 [P82125-1]
ENSSSCT00005029849; ENSSSCP00005018168; ENSSSCG00005018482 [P82125-1]
ENSSSCT00025032851; ENSSSCP00025013710; ENSSSCG00025024226 [P82125-1]
ENSSSCT00035029808; ENSSSCP00035011546; ENSSSCG00035022798 [P82125-1]
ENSSSCT00045048830; ENSSSCP00045033959; ENSSSCG00045028552 [P82125-1]
ENSSSCT00055002173; ENSSSCP00055001633; ENSSSCG00055001205 [P82125-1]
ENSSSCT00060086891; ENSSSCP00060037590; ENSSSCG00060063649 [P82125-1]
ENSSSCT00065085447; ENSSSCP00065037345; ENSSSCG00065062289 [P82125-1]
ENSSSCT00065085458; ENSSSCP00065037352; ENSSSCG00065062289 [P82125-1]
ENSSSCT00070011622; ENSSSCP00070009575; ENSSSCG00070006087 [P82125-1]
ENSSSCT00070011628; ENSSSCP00070009581; ENSSSCG00070006087 [P82125-1]
GeneIDi733633
KEGGissc:733633

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
83592
VGNCiVGNC:96003, AKR1E2

Phylogenomic databases

eggNOGiKOG1577, Eukaryota
GeneTreeiENSGT00940000153272
HOGENOMiCLU_023205_0_0_1
InParanoidiP82125
OMAiKLWPTDQ
OrthoDBi1016440at2759
TreeFamiTF106492

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-17139

Gene expression databases

BgeeiENSSSCG00000026214, Expressed in adult mammalian kidney and 31 other tissues
ExpressionAtlasiP82125, baseline and differential
GenevisibleiP82125, SS

Family and domain databases

CDDicd19110, AKR_AKR1E1-2, 1 hit
Gene3Di3.20.20.100, 1 hit
InterProiView protein in InterPro
IPR020471, AKR
IPR044484, AKR1E2
IPR018170, Aldo/ket_reductase_CS
IPR023210, NADP_OxRdtase_dom
IPR036812, NADP_OxRdtase_dom_sf
PfamiView protein in Pfam
PF00248, Aldo_ket_red, 1 hit
PIRSFiPIRSF000097, AKR, 1 hit
PRINTSiPR00069, ALDKETRDTASE
SUPFAMiSSF51430, SSF51430, 1 hit
PROSITEiView protein in PROSITE
PS00798, ALDOKETO_REDUCTASE_1, 1 hit
PS00062, ALDOKETO_REDUCTASE_2, 1 hit
PS00063, ALDOKETO_REDUCTASE_3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAKCL2_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P82125
Secondary accession number(s): Q1KLB5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: June 16, 2009
Last modified: September 29, 2021
This is version 106 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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