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Protein

Pardaxin P-4

Gene
N/A
Organism
Pardachirus marmoratus (Finless sole) (Achirus marmoratus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Exhibits unusual shark repellent and surfactant properties. Forms voltage-dependent, ion-permeable channels in membranes. At high concentration causes cell membrane lysis.2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionToxin
Biological processIon transport, Transport

Protein family/group databases

TCDBi1.A.66.1.1 the pardaxin (pardaxin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Pardaxin P-4
Alternative name(s):
Pardaxin P1a
Pardaxin Pa4
OrganismiPardachirus marmoratus (Finless sole) (Achirus marmoratus)
Taxonomic identifieri31087 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataCarangariaPleuronectiformesPleuronectoideiSoleidaePardachirus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Secreted, Target cell membrane, Target membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000447851 – 33Pardaxin P-4Add BLAST33

Interactioni

Subunit structurei

Monomer. In aqueous solution exists as a tetramer (By similarity).By similarity

Structurei

Secondary structure

133
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 5Combined sources3
Helixi6 – 9Combined sources4
Turni10 – 14Combined sources5
Helixi15 – 25Combined sources11
Turni26 – 31Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XC0NMR-A1-33[»]
2KNSNMR-A1-33[»]
ProteinModelPortaliP81861
SMRiP81861
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP81861

Family & Domainsi

Domaini

Consists of a C-terminal hydrophilic region and a predominantly hydrophobic remainder.

Sequence similaritiesi

Belongs to the pardaxin family.Curated

Keywords - Domaini

Transmembrane

Family and domain databases

InterProiView protein in InterPro
IPR009990 Pardaxin
PfamiView protein in Pfam
PF07425 Pardaxin, 1 hit
PIRSFiPIRSF037561 Pardaxin, 1 hit

Sequencei

Sequence statusi: Complete.

P81861-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
GFFALIPKII SSPLFKTLLS AVGSALSSSG GQE
Length:33
Mass (Da):3,324
Last modified:May 30, 2000 - v1
Checksum:i5ABFF96A16FC910D
GO

Similar proteinsi

Entry informationi

Entry nameiPAP4_PARMA
AccessioniPrimary (citable) accession number: P81861
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: November 22, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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