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UniProtKB - P80857 (SODF_SACS2)
Protein
Superoxide dismutase [Fe]
Gene
sod
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Status
Functioni
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activityi
- EC:1.15.1.1
Cofactori
Fe cationNote: Binds 1 Fe cation per subunit.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 34 | Iron | 1 | |
Metal bindingi | 85 | Iron | 1 | |
Metal bindingi | 171 | Iron | 1 | |
Metal bindingi | 175 | Iron | 1 |
GO - Molecular functioni
- manganese ion binding Source: GO_Central
- superoxide dismutase activity Source: GO_Central
Keywordsi
Molecular function | Oxidoreductase |
Ligand | Iron, Metal-binding |
Enzyme and pathway databases
BRENDAi | 1.15.1.1, 6163 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:sod Ordered Locus Names:SSO0316 |
Organismi | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
Taxonomic identifieri | 273057 [NCBI] |
Taxonomic lineagei | Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Saccharolobus › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed1 Publication | |||
ChainiPRO_0000160010 | 2 – 211 | Superoxide dismutase [Fe]Add BLAST | 210 |
Interactioni
Subunit structurei
Homotetramer.
1 PublicationProtein-protein interaction databases
STRINGi | 273057.SSO0316 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P80857 |
SMRi | P80857 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P80857 |
Family & Domainsi
Sequence similaritiesi
Belongs to the iron/manganese superoxide dismutase family.Curated
Phylogenomic databases
eggNOGi | arCOG04147, Archaea |
HOGENOMi | CLU_031625_2_2_2 |
InParanoidi | P80857 |
OMAi | KWGSFDK |
PhylomeDBi | P80857 |
Family and domain databases
Gene3Di | 1.10.287.990, 1 hit 3.55.40.20, 1 hit |
InterProi | View protein in InterPro IPR001189, Mn/Fe_SOD IPR019833, Mn/Fe_SOD_BS IPR019832, Mn/Fe_SOD_C IPR019831, Mn/Fe_SOD_N IPR036324, Mn/Fe_SOD_N_sf IPR036314, SOD_C_sf |
Pfami | View protein in Pfam PF02777, Sod_Fe_C, 1 hit PF00081, Sod_Fe_N, 1 hit |
PIRSFi | PIRSF000349, SODismutase, 1 hit |
PRINTSi | PR01703, MNSODISMTASE |
SUPFAMi | SSF46609, SSF46609, 1 hit SSF54719, SSF54719, 1 hit |
PROSITEi | View protein in PROSITE PS00088, SOD_MN, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P80857-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLQIQFKKY ELPPLPYKID ALEPYISKDI IDVHYNGHHK GYVNGANSLL
60 70 80 90 100
ERLEKVVKGD LQTGQYDIQG IIRGLTFNIN GHKLHALYWE NMAPSGKGGG
110 120 130 140 150
KPGGALADLI NKQYGSFDRF KQVFTETANS LPGTGWAVLY YDTESGNLQI
160 170 180 190 200
MTFENHFQNH IAEIPIILIL DEFEHAYYLQ YKNKRADYVN AWWNVVNWDA
210
AEKKLQKYLT K
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012620 Genomic DNA Translation: BAA75509.1 Y15326 Genomic DNA Translation: CAA75583.1 AE006641 Genomic DNA Translation: AAK40652.1 |
PIRi | E90174 |
RefSeqi | WP_009990609.1, NC_002754.1 |
Genome annotation databases
EnsemblBacteriai | AAK40652; AAK40652; SSO0316 |
GeneIDi | 44129290 |
KEGGi | sso:SSO0316 |
PATRICi | fig|273057.12.peg.310 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012620 Genomic DNA Translation: BAA75509.1 Y15326 Genomic DNA Translation: CAA75583.1 AE006641 Genomic DNA Translation: AAK40652.1 |
PIRi | E90174 |
RefSeqi | WP_009990609.1, NC_002754.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1WB7 | X-ray | 2.24 | A/B | 2-211 | [»] | |
1WB8 | X-ray | 2.30 | A/B | 2-211 | [»] | |
AlphaFoldDBi | P80857 | |||||
SMRi | P80857 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 273057.SSO0316 |
Genome annotation databases
EnsemblBacteriai | AAK40652; AAK40652; SSO0316 |
GeneIDi | 44129290 |
KEGGi | sso:SSO0316 |
PATRICi | fig|273057.12.peg.310 |
Phylogenomic databases
eggNOGi | arCOG04147, Archaea |
HOGENOMi | CLU_031625_2_2_2 |
InParanoidi | P80857 |
OMAi | KWGSFDK |
PhylomeDBi | P80857 |
Enzyme and pathway databases
BRENDAi | 1.15.1.1, 6163 |
Miscellaneous databases
EvolutionaryTracei | P80857 |
Family and domain databases
Gene3Di | 1.10.287.990, 1 hit 3.55.40.20, 1 hit |
InterProi | View protein in InterPro IPR001189, Mn/Fe_SOD IPR019833, Mn/Fe_SOD_BS IPR019832, Mn/Fe_SOD_C IPR019831, Mn/Fe_SOD_N IPR036324, Mn/Fe_SOD_N_sf IPR036314, SOD_C_sf |
Pfami | View protein in Pfam PF02777, Sod_Fe_C, 1 hit PF00081, Sod_Fe_N, 1 hit |
PIRSFi | PIRSF000349, SODismutase, 1 hit |
PRINTSi | PR01703, MNSODISMTASE |
SUPFAMi | SSF46609, SSF46609, 1 hit SSF54719, SSF54719, 1 hit |
PROSITEi | View protein in PROSITE PS00088, SOD_MN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SODF_SACS2 | |
Accessioni | P80857Primary (citable) accession number: P80857 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 141 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families