UniProtKB - P80667 (PEX13_YEAST)
Protein
Peroxisomal membrane protein PAS20
Gene
PEX13
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Component of the peroxisomal translocation machinery with PEX14 and PEX17. Interacts with the PTS1 receptor (PAS10/PEX5).
Miscellaneous
Present with 7900 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- protein-macromolecule adaptor activity Source: SGD
GO - Biological processi
- protein import into peroxisome matrix, docking Source: SGD
Keywordsi
Biological process | Protein transport, Transport |
Enzyme and pathway databases
Reactomei | R-SCE-9033241, Peroxisomal protein import R-SCE-9603798, Class I peroxisomal membrane protein import |
Protein family/group databases
TCDBi | 3.A.20.1.5, the peroxisomal protein importer (ppi) family |
Names & Taxonomyi
Protein namesi | Recommended name: Peroxisomal membrane protein PAS20Alternative name(s): Peroxin-13 |
Gene namesi | Name:PEX13 Synonyms:PAS20 Ordered Locus Names:YLR191W ORF Names:L9470.1 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004181, PEX13 |
VEuPathDBi | FungiDB:YLR191W |
Subcellular locationi
Peroxisome
Peroxisome
- peroxisomal membrane Source: SGD
Other locations
- integral component of membrane Source: UniProtKB-KW
- peroxisomal importomer complex Source: SGD
- Pex17p-Pex14p docking complex Source: SGD
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 263 | LumenalSequence analysisAdd BLAST | 263 | |
Transmembranei | 264 – 280 | HelicalSequence analysisAdd BLAST | 17 | |
Topological domaini | 281 – 386 | CytoplasmicSequence analysisAdd BLAST | 106 |
Keywords - Cellular componenti
Membrane, PeroxisomePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000058324 | 1 – 386 | Peroxisomal membrane protein PAS20Add BLAST | 386 |
Proteomic databases
MaxQBi | P80667 |
PaxDbi | P80667 |
PRIDEi | P80667 |
PTM databases
iPTMneti | P80667 |
Interactioni
Binary interactionsi
Hide detailsP80667
Protein-protein interaction databases
BioGRIDi | 31461, 272 interactors |
ComplexPortali | CPX-1904, Peroxisomal docking Pex13/Pex14/Pex 15 complex |
DIPi | DIP-2473N |
ELMi | P80667 |
IntActi | P80667, 80 interactors |
MINTi | P80667 |
STRINGi | 4932.YLR191W |
Miscellaneous databases
RNActi | P80667, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P80667 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P80667 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 306 – 372 | SH3PROSITE-ProRule annotationAdd BLAST | 67 |
Sequence similaritiesi
Belongs to the peroxin-13 family.Curated
Keywords - Domaini
SH3 domain, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3875, Eukaryota |
GeneTreei | ENSGT00390000016883 |
HOGENOMi | CLU_034386_2_0_1 |
InParanoidi | P80667 |
OMAi | WIQGRTR |
Family and domain databases
InterProi | View protein in InterPro IPR007223, Peroxin-13_N IPR035463, Pex13 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR19332, PTHR19332, 1 hit |
Pfami | View protein in Pfam PF04088, Peroxin-13_N, 1 hit PF00018, SH3_1, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS50002, SH3, 1 hit |
i Sequence
Sequence statusi: Complete.
P80667-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSTAVPRPK PWETSASLEE PQRNAQSLSA MMTSNQQDSR PTEESNNSNS
60 70 80 90 100
ASESAPEVLP RPAALNSSGT YGESNTIPGI YGNSNYGIPY DNNPYSMNSI
110 120 130 140 150
YGNSIGRYGY GGSYYGNNYG SFYGGGYGAG AGYGMNNGSG LGESTKATFQ
160 170 180 190 200
LIESLIGAVT GFAQMLESTY MATHNSFFTM ISVAEQFGNL KEMLGSFFGI
210 220 230 240 250
FAIMKFLKKI LYRATKGRLG IPPKNFAESE GSKNKLIEDF QKFNDSGTIN
260 270 280 290 300
SNEKATRRKI SWKPLLFFLM AVFGFPYLLN KFITKLQTSG TIRASQGNGS
310 320 330 340 350
EPIDPSKLEF ARALYDFVPE NPEMEVALKK GDLMAILSKK DPLGRDSDWW
360 370 380
KVRTKNGNIG YIPYNYIEII KRRKKIEHVD DETRTH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | S82971 Genomic DNA Translation: AAB46885.1 U37420 Genomic DNA Translation: AAA79308.1 U17246 Genomic DNA Translation: AAB67453.1 U14913 Genomic DNA Translation: AAB67448.1 BK006945 Genomic DNA Translation: DAA09510.1 |
PIRi | S51436 |
RefSeqi | NP_013292.1, NM_001182078.1 |
Genome annotation databases
EnsemblFungii | YLR191W_mRNA; YLR191W; YLR191W |
GeneIDi | 850888 |
KEGGi | sce:YLR191W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | S82971 Genomic DNA Translation: AAB46885.1 U37420 Genomic DNA Translation: AAA79308.1 U17246 Genomic DNA Translation: AAB67453.1 U14913 Genomic DNA Translation: AAB67448.1 BK006945 Genomic DNA Translation: DAA09510.1 |
PIRi | S51436 |
RefSeqi | NP_013292.1, NM_001182078.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1JQQ | X-ray | 2.65 | A/B/C/D | 299-386 | [»] | |
1N5Z | X-ray | 2.70 | A/B | 299-386 | [»] | |
1NM7 | NMR | - | A | 310-370 | [»] | |
2V1R | X-ray | 2.10 | A/B | 299-374 | [»] | |
SMRi | P80667 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 31461, 272 interactors |
ComplexPortali | CPX-1904, Peroxisomal docking Pex13/Pex14/Pex 15 complex |
DIPi | DIP-2473N |
ELMi | P80667 |
IntActi | P80667, 80 interactors |
MINTi | P80667 |
STRINGi | 4932.YLR191W |
Protein family/group databases
TCDBi | 3.A.20.1.5, the peroxisomal protein importer (ppi) family |
PTM databases
iPTMneti | P80667 |
Proteomic databases
MaxQBi | P80667 |
PaxDbi | P80667 |
PRIDEi | P80667 |
Genome annotation databases
EnsemblFungii | YLR191W_mRNA; YLR191W; YLR191W |
GeneIDi | 850888 |
KEGGi | sce:YLR191W |
Organism-specific databases
SGDi | S000004181, PEX13 |
VEuPathDBi | FungiDB:YLR191W |
Phylogenomic databases
eggNOGi | KOG3875, Eukaryota |
GeneTreei | ENSGT00390000016883 |
HOGENOMi | CLU_034386_2_0_1 |
InParanoidi | P80667 |
OMAi | WIQGRTR |
Enzyme and pathway databases
Reactomei | R-SCE-9033241, Peroxisomal protein import R-SCE-9603798, Class I peroxisomal membrane protein import |
Miscellaneous databases
EvolutionaryTracei | P80667 |
PROi | PR:P80667 |
RNActi | P80667, protein |
Family and domain databases
InterProi | View protein in InterPro IPR007223, Peroxin-13_N IPR035463, Pex13 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR19332, PTHR19332, 1 hit |
Pfami | View protein in Pfam PF04088, Peroxin-13_N, 1 hit PF00018, SH3_1, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS50002, SH3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PEX13_YEAST | |
Accessioni | P80667Primary (citable) accession number: P80667 Secondary accession number(s): D6VYJ4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 10, 2021 | |
This is version 171 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XII
Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families