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Protein

Pyrogallol hydroxytransferase large subunit

Gene

athL

Organism
Pelobacter acidigallici
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Isomerisation of pyrogallol to phloroglucin.

Catalytic activityi

1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.

Cofactori

Mo-bis(molybdopterin guanine dinucleotide)1 PublicationNote: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi175Molybdenum1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, Molybdenum

Enzyme and pathway databases

BRENDAi1.97.1.2 4585

Protein family/group databases

TCDBi5.A.3.7.1 the prokaryotic molybdopterin-containing oxidoreductase (pmo) family

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrogallol hydroxytransferase large subunit (EC:1.97.1.2)
Alternative name(s):
Transhydroxylase subunit alpha
Gene namesi
Name:athL
OrganismiPelobacter acidigallici
Taxonomic identifieri35816 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesDesulfuromonadaceaePelobacter

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000632422 – 875Pyrogallol hydroxytransferase large subunitAdd BLAST874

Proteomic databases

PRIDEiP80563

Interactioni

Subunit structurei

Heterodimer of a large and a small subunit.1 Publication

Structurei

Secondary structure

1875
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP80563
SMRiP80563
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP80563

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR009010 Asp_de-COase-like_dom_sf
IPR006657 MoPterin_dinucl-bd_dom
IPR006656 Mopterin_OxRdtase
PfamiView protein in Pfam
PF00384 Molybdopterin, 1 hit
PF01568 Molydop_binding, 1 hit
SUPFAMiSSF50692 SSF50692, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P80563-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEVVRLTNS STGGPVFVYV KDGKIIRMTP MDFDDAVDAP SWKIEARGKT
60 70 80 90 100
FTPPRKTSIA PYTAGFKSMI YSDLRIPYPM KRKSFDPNGE RNPQLRGAGL
110 120 130 140 150
SKQDPWSDYE RISWDEATDI VVAEINRIKH AYGPSAILST PSSHHMWGNV
160 170 180 190 200
GYRHSTYFRF MNMMGFTYAD HNPDSWEGWH WGGMHMWGFS WRLGNPEQYD
210 220 230 240 250
LLEDGLKHAE MIVFWSSDPE TNSGIYAGFE SNIRRQWLKD LGVDFVFIDP
260 270 280 290 300
HMNHTARLVA DKWFSPKIGT DHALSFAIAY TWLKEDSYDK EYVAANAHGF
310 320 330 340 350
EEWADYVLGK TDGTPKTCEW AEEESGVPAC EIRALARQWA KKNTYLAAGG
360 370 380 390 400
LGGWGGACRA SHGIEWARGM IALATMQGMG KPGSNMWSTT QGVPLDYEFY
410 420 430 440 450
FPGYAEGGIS GDCENSAAGF KFAWRMFDGK TTFPSPSNLN TSAGQHIPRL
460 470 480 490 500
KIPECIMGGK FQWSGKGFAG GDISHQLHQY EYPAPGYSKI KMFWKYGGPH
510 520 530 540 550
LGTMTATNRY AKMYTHDSLE FVVSQSIWFE GEVPFADIIL PACTNFERWD
560 570 580 590 600
ISEFANCSGY IPDNYQLCNH RVISLQAKCI EPVGESMSDY EIYRLFAKKL
610 620 630 640 650
NIEEMFSEGK DELAWCEQYF NATDMPKYMT WDEFFKKGYF VVPDNPNRKK
660 670 680 690 700
TVALRWFAEG REKDTPDWGP RLNNQVCRKG LQTTTGKVEF IATSLKNFEE
710 720 730 740 750
QGYIDEHRPS MHTYVPAWES QKHSPLAVKY PLGMLSPHPR FSMHTMGDGK
760 770 780 790 800
NSYMNYIKDH RVEVDGYKYW IMRVNSIDAE ARGIKNGDLI RAYNDRGSVI
810 820 830 840 850
LAAQVTECLQ PGTVHSYESC AVYDPLGTAG KSADRGGCIN ILTPDRYISK
860 870
YACGMANNTA LVEIEKWDGD KYEIY
Length:875
Mass (Da):99,261
Last modified:January 23, 2007 - v3
Checksum:iB5D7DE5FAEF53A61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243850 Genomic DNA Translation: CAB50913.1
PIRiS65430

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243850 Genomic DNA Translation: CAB50913.1
PIRiS65430

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V4CX-ray2.35A/C/E/G/I/K/M/O/Q/S/U/W1-875[»]
4V4DX-ray2.20A/C/E/G/I/K/M/O/Q/S/U/W1-875[»]
4V4EX-ray2.00A/C/E/G/I/K/M/O/Q/S/U/W1-875[»]
ProteinModelPortaliP80563
SMRiP80563
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi5.A.3.7.1 the prokaryotic molybdopterin-containing oxidoreductase (pmo) family

Proteomic databases

PRIDEiP80563

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi1.97.1.2 4585

Miscellaneous databases

EvolutionaryTraceiP80563

Family and domain databases

InterProiView protein in InterPro
IPR009010 Asp_de-COase-like_dom_sf
IPR006657 MoPterin_dinucl-bd_dom
IPR006656 Mopterin_OxRdtase
PfamiView protein in Pfam
PF00384 Molybdopterin, 1 hit
PF01568 Molydop_binding, 1 hit
SUPFAMiSSF50692 SSF50692, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPGTL_PELAC
AccessioniPrimary (citable) accession number: P80563
Secondary accession number(s): Q9S354
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 83 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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