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Protein

Cytochrome c oxidase subunit 3

Gene

COX3

Organism
Allomyces macrogynus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COX3
Encoded oniMitochondrion
OrganismiAllomyces macrogynus
Taxonomic identifieri28583 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisBlastocladiomycotaBlastocladiomycetesBlastocladialesBlastocladiaceaeAllomyces

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei47 – 67HelicalSequence analysisAdd BLAST21
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21
Transmembranei137 – 157HelicalSequence analysisAdd BLAST21
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Transmembranei208 – 228HelicalSequence analysisAdd BLAST21
Transmembranei248 – 268HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001837301 – 274Cytochrome c oxidase subunit 3Add BLAST274

Structurei

3D structure databases

ProteinModelPortaliP80439
SMRiP80439
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 1 hit
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 1 hit
SUPFAMiSSF81452 SSF81452, 1 hit
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit

Sequencei

Sequence statusi: Complete.

P80439-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKKLINQFK SFQVHPYHLV EPSPWPLGAS VACLILTLGG VMKFHGFAAG
60 70 80 90 100
DIGLPLGLIL VLASMLLWWR DVIREATYQG HHTKTVKYGI TLGVVLFIVS
110 120 130 140 150
EILLFFSLFW AFFHSSLAPS VELGSTWPPV GIEPLNPFEV PLLNTIILLT
160 170 180 190 200
SGCTITVSHA KIISGDRGAT ILYLILTILL AWMFLGLQWV EYVNAPFTIA
210 220 230 240 250
DSVYGSTFFV ATGFHGLHVM IGTIFLTVSL NRILSYHLTS GHHLGYEAAI
260 270
WYWHVVDVIW LFLYVSVYYW GSNV
Length:274
Mass (Da):30,630
Last modified:November 1, 1995 - v1
Checksum:i4B2A835ED31386F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41288 Genomic DNA Translation: AAC49226.1
PIRiS63643
RefSeqiNP_043725.1, NC_001715.1

Genome annotation databases

GeneIDi801893

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41288 Genomic DNA Translation: AAC49226.1
PIRiS63643
RefSeqiNP_043725.1, NC_001715.1

3D structure databases

ProteinModelPortaliP80439
SMRiP80439
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi801893

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 1 hit
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 1 hit
SUPFAMiSSF81452 SSF81452, 1 hit
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCOX3_ALLMA
AccessioniPrimary (citable) accession number: P80439
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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