UniProtKB - P80378 (RS15_THETH)
Protein
30S ribosomal protein S15
Gene
rpsO
Organism
Thermus thermophilus
Status
Functioni
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.UniRule annotation
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 30S ribosomal protein S15UniRule annotation |
Gene namesi | Name:rpsOUniRule annotation Synonyms:rps15UniRule annotation |
Organismi | Thermus thermophilus |
Taxonomic identifieri | 274 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000115572 | 2 – 89 | 30S ribosomal protein S15Add BLAST | 88 |
Interactioni
Subunit structurei
Part of the 30S ribosomal subunit.
Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.
UniRule annotationProtein-protein interaction databases
DIPi | DIP-6174N |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P80378 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P80378 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uS15 family.UniRule annotation
Family and domain databases
CDDi | cd00353, Ribosomal_S15p_S13e, 1 hit |
HAMAPi | MF_01343_B, Ribosomal_S15_B, 1 hit |
InterProi | View protein in InterPro IPR000589, Ribosomal_S15 IPR005290, Ribosomal_S15_bac-type IPR009068, S15_NS1_RNA-bd |
PANTHERi | PTHR23321, PTHR23321, 1 hit |
Pfami | View protein in Pfam PF00312, Ribosomal_S15, 1 hit |
SMARTi | View protein in SMART SM01387, Ribosomal_S15, 1 hit |
SUPFAMi | SSF47060, SSF47060, 1 hit |
TIGRFAMsi | TIGR00952, S15_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00362, RIBOSOMAL_S15, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P80378-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPITKEEKQK VIQEFARFPG DTGSTEVQVA LLTLRINRLS EHLKVHKKDH
60 70 80
HSHRGLLMMV GQRRRLLRYL QREDPERYRA LIEKLGIRG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z37726 Genomic DNA Translation: CAA85782.1 Z84207 Genomic DNA Translation: CAB06340.1 |
RefSeqi | WP_008632621.1, NZ_VHHQ01000002.1 |
Genome annotation databases
GeneIDi | 3169463 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z37726 Genomic DNA Translation: CAA85782.1 Z84207 Genomic DNA Translation: CAB06340.1 |
RefSeqi | WP_008632621.1, NZ_VHHQ01000002.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1AB3 | NMR | - | A | 2-89 | [»] | |
1DK1 | X-ray | 2.80 | A | 2-87 | [»] | |
1F7Y | X-ray | 2.80 | A | 1-89 | [»] | |
1KUQ | X-ray | 2.84 | A | 1-87 | [»] | |
1TWT | model | - | R | 2-89 | [»] | |
2FKX | NMR | - | A | 2-89 | [»] | |
4V49 | X-ray | 8.70 | O | 2-89 | [»] | |
4V8X | X-ray | 3.35 | AO/CO | 1-89 | [»] | |
SMRi | P80378 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
DIPi | DIP-6174N |
Genome annotation databases
GeneIDi | 3169463 |
Miscellaneous databases
EvolutionaryTracei | P80378 |
Family and domain databases
CDDi | cd00353, Ribosomal_S15p_S13e, 1 hit |
HAMAPi | MF_01343_B, Ribosomal_S15_B, 1 hit |
InterProi | View protein in InterPro IPR000589, Ribosomal_S15 IPR005290, Ribosomal_S15_bac-type IPR009068, S15_NS1_RNA-bd |
PANTHERi | PTHR23321, PTHR23321, 1 hit |
Pfami | View protein in Pfam PF00312, Ribosomal_S15, 1 hit |
SMARTi | View protein in SMART SM01387, Ribosomal_S15, 1 hit |
SUPFAMi | SSF47060, SSF47060, 1 hit |
TIGRFAMsi | TIGR00952, S15_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00362, RIBOSOMAL_S15, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RS15_THETH | |
Accessioni | P80378Primary (citable) accession number: P80378 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | January 23, 2007 | |
Last modified: | April 7, 2021 | |
This is version 123 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families