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Protein

Protein HIRA

Gene

HIRA

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cooperates with ASF1A to promote replication-independent chromatin assembly (By similarity). May regulate the transcription of a variety of genes controlling cell growth.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • transcription corepressor activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Repressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein HIRA
Short name:
cHIRA
Alternative name(s):
TUP1-like enhancer of split protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HIRA
Synonyms:TUPLE1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi43 – 44WN → AA: Abrogates interaction with RBBP4. 1 Publication2
Mutagenesisi121 – 122WR → AA: Abrogates interaction with RBBP4. 1 Publication2
Mutagenesisi182 – 183WD → AA: Abrogates interaction with RBBP4. 1 Publication2
Mutagenesisi336 – 337WT → AA: Abrogates interaction with RBBP4 and impairs transcriptional repression. 1 Publication2
Mutagenesisi993L → A: Abrogates interaction with HDAC2 and impairs transcriptional repression. 2 Publications1
Mutagenesisi996L → A: Abrogates interaction with HDAC2. 2 Publications1
Mutagenesisi997L → A: Abrogates interaction with HDAC2. 2 Publications1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000510181 – 1019Protein HIRAAdd BLAST1019

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P79987

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed from gastrulation onwards with predominant expression in the neuroepithelium during neurulation. Expressed in regions of the embryo containing migrating neural crest cells, particularly those emanating from rhombomeres 4 and 6. Expressed throughout the rostral mesenchyme with higher levels of expression in regions containing neural crest cells. At later stages strong expression is seen in the neural crest derived regions of the head, the branchial arches and the pharyngeal pouches. Expression at the rhombomere boundaries increases around stage 16.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ASF1, HDAC1, HDAC2 and RBBP4.3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
ASF1Q3C1E92EBI-996848,EBI-996834

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
675113, 4 interactors

Protein interaction database and analysis system

More...
IntActi
P79987, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9031.ENSGALP00000039165

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P79987

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati11 – 53WD 1PROSITE-ProRule annotation1 PublicationAdd BLAST43
Repeati68 – 107WD 2PROSITE-ProRule annotation1 PublicationAdd BLAST40
Repeati129 – 168WD 3PROSITE-ProRule annotation1 PublicationAdd BLAST40
Repeati172 – 211WD 4PROSITE-ProRule annotation1 PublicationAdd BLAST40
Repeati220 – 263WD 5PROSITE-ProRule annotation1 PublicationAdd BLAST44
Repeati266 – 322WD 6PROSITE-ProRule annotation1 PublicationAdd BLAST57
Repeati326 – 367WD 7PROSITE-ProRule annotation1 PublicationAdd BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni23 – 443Interaction with RBBP4Add BLAST421
Regioni444 – 1019Interaction with HDAC1Add BLAST576
Regioni960 – 1019Interaction with HDAC2Add BLAST60

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WD repeat HIR1 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0973 Eukaryota
ENOG410XP1H LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007670

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG005969

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P79987

KEGG Orthology (KO)

More...
KOi
K11293

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P79987

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031120 HIR1
IPR011494 Hira
IPR019015 HIRA_B_motif
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13831 PTHR13831, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07569 Hira, 1 hit
PF09453 HIRA_B, 1 hit
PF00400 WD40, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P79987-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLKPTWVN HNGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMAPVLK
60 70 80 90 100
EEDEKNENIP KMLCQMDNHL ACVNCVRWSN NGVYLASGGD DKLIMVWKRA
110 120 130 140 150
AYIGPSTVFG SSSKLTNVEQ WRCVSILRSH SGDVMDVAWS PHDAWLASCS
160 170 180 190 200
VDNTVVIWNA VKFPEILATL KGHSGLVKGL TWDPVGKYIA SQADDRSLKV
210 220 230 240 250
WRTMDWQLET SITKPFDECG GTTHVLRLSW SPDGHYLVSA HAMNNSGPTA
260 270 280 290 300
QIIERDGWKT NMDFVGHRKA VTVVKFNPKI FKKKQKNGSS TKSSCPYCCC
310 320 330 340 350
AVGSKDRSLS VWLTCLKRPL VVIHELFDKS IMDISWTLNG LGILVCSMDG
360 370 380 390 400
SVAFLDFSQD ELGDPLSEEE KSNIHQSTYG KSLAIMTEAQ LSTTIIENPE
410 420 430 440 450
MLKYQQRQQQ QQAEQKNASI REASGAATTA PKVASMVNGE SLEDIRKNLL
460 470 480 490 500
KKQVETRTAD GRRRITPLCI AQLDTGDFST AFFNSIPISG TLAGSIMSSQ
510 520 530 540 550
NNQQLMSLDS NAANSLNTSK PSAEPTAASI KPTDDAASKD GVNATSVSTA
560 570 580 590 600
PPASSSSVLT TPSKIEPMKA FDSRFTERSK ATSGTAVVTN TNQTVVDRLK
610 620 630 640 650
DQNLIKDNKP KDILESSSDS EEKIPAAKPL SAPKRKLELE GETVEKKKKG
660 670 680 690 700
RPRKDSRLVP VTLTVQSPAA LASEKDAACI SAPALALKLP TPIPQKSFTL
710 720 730 740 750
QVSSDPSMYL EVENEMTTVG GSKLSRLKCN REGKEWETVL TSRILTAAGS
760 770 780 790 800
CEIVCVACEK RMLSVFSACG RRLLPPIILN TPISTLHCTG SYIMTLTTAA
810 820 830 840 850
TLSVWDVHKQ TVIVRDESLQ TILSGSDTTV SQILLTQHGI PVMSMSDGKA
860 870 880 890 900
YCFNPSLSTW NLVSDKQDSL AQCADFRSSL PSQEAMLCSG PLAVIQGRTS
910 920 930 940 950
NSGRQAARLF SMPHLVQQET TLAYLENQIA AALMLQSSHE YRHWLLIYAR
960 970 980 990 1000
YLVNEGFEYR LRELCKDLLG PVHYSRGSQW ESTVMGLRKR ELLKELLPVI
1010
GQNLFQRLFT EYQEQLDIL
Length:1,019
Mass (Da):112,074
Last modified:May 1, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i24DCECAFA52E9F60
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti124Missing in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti159N → NA in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti206W → G in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti230W → G in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti315C → S in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti329K → E in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti356 – 357DF → NS in CAA67754 (PubMed:9063744).Curated2
Sequence conflicti367S → T in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti371 – 376KSNIHQ → NSPFYH in CAA67754 (PubMed:9063744).Curated6
Sequence conflicti384A → P in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti388E → D in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti394 – 395TI → IT in CAA67754 (PubMed:9063744).Curated2
Sequence conflicti402 – 405LKYQ → SQAIE in CAA67754 (PubMed:9063744).Curated4
Sequence conflicti423 – 436ASGAA…KVASM → MGTTTSVAGI in CAA67754 (PubMed:9063744).CuratedAdd BLAST14
Sequence conflicti446R → L in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti450L → F in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti488I → L in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti500 – 501QN → HS in CAA67754 (PubMed:9063744).Curated2
Sequence conflicti516L → F in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti526T → VA in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti530I → V in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti538S → N in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti541G → S in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti585T → S in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti604L → F in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti607D → E in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti626A → V in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti672A → V in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti679 – 680CI → WL in CAA67754 (PubMed:9063744).Curated2
Sequence conflicti729C → G in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti753I → K in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti763L → Q in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti766 – 768FSA → YSD in CAA67754 (PubMed:9063744).Curated3
Sequence conflicti816D → E in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti827D → E in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti841 – 847PVMSMSD → AVLALSE in CAA67754 (PubMed:9063744).Curated7
Sequence conflicti853F → S in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti893A → T in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti976R → T in CAA67754 (PubMed:9063744).Curated1
Sequence conflicti992L → H in BAC11842 (PubMed:15527972).Curated1
Sequence conflicti1004L → LR in CAA67754 (PubMed:9063744).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X99375 mRNA Translation: CAA67754.1
AB091180 mRNA Translation: BAC11842.1

NCBI Reference Sequences

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RefSeqi
NP_989563.2, NM_204232.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Gga.2250

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
374074

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gga:374074

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X99375 mRNA Translation: CAA67754.1
AB091180 mRNA Translation: BAC11842.1
RefSeqiNP_989563.2, NM_204232.2
UniGeneiGga.2250

3D structure databases

ProteinModelPortaliP79987
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi675113, 4 interactors
IntActiP79987, 1 interactor
STRINGi9031.ENSGALP00000039165

Proteomic databases

PaxDbiP79987

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi374074
KEGGigga:374074

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7290

Phylogenomic databases

eggNOGiKOG0973 Eukaryota
ENOG410XP1H LUCA
HOGENOMiHOG000007670
HOVERGENiHBG005969
InParanoidiP79987
KOiK11293
PhylomeDBiP79987

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P79987

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR031120 HIR1
IPR011494 Hira
IPR019015 HIRA_B_motif
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR13831 PTHR13831, 1 hit
PfamiView protein in Pfam
PF07569 Hira, 1 hit
PF09453 HIRA_B, 1 hit
PF00400 WD40, 4 hits
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHIRA_CHICK
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P79987
Secondary accession number(s): Q8JIE6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 1, 2007
Last modified: November 7, 2018
This is version 115 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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