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Entry version 122 (12 Aug 2020)
Sequence version 1 (01 May 1997)
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Protein

Propionyl-CoA carboxylase beta chain, mitochondrial

Gene

PCCB

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites (PubMed:13752080). Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:13752080). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA at a much lower rate (PubMed:13752080). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (PubMed:13752080).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.2 mM for propanoyl-CoA1 Publication
  2. KM=1.5 mM for butanoyl-CoA1 Publication

    pH dependencei

    Optimum pH is 8.0-8.2 for the propionyl-CoA carboxylase activity as measured with the holoenzyme.1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: propanoyl-CoA degradation

    This protein is involved in step 1 of the subpathway that synthesizes succinyl-CoA from propanoyl-CoA.1 Publication
    Proteins known to be involved in the 3 steps of the subpathway in this organism are:
    1. Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha, Propanoyl-CoA:carbon dioxide ligase subunit alpha, Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha, Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA), Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB), Propanoyl-CoA:carbon dioxide ligase subunit alpha (PCCA)
    2. no protein annotated in this organism
    3. no protein annotated in this organism
    This subpathway is part of the pathway propanoyl-CoA degradation, which is itself part of Metabolic intermediate metabolism.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes succinyl-CoA from propanoyl-CoA, the pathway propanoyl-CoA degradation and in Metabolic intermediate metabolism.

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • ATP binding Source: UniProtKB-KW
    • propionyl-CoA carboxylase activity Source: UniProtKB

    GO - Biological processi

    • short-chain fatty acid catabolic process Source: UniProtKB

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionLigase
    LigandATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-SSC-196780, Biotin transport and metabolism
    R-SSC-71032, Propionyl-CoA catabolism

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00945;UER00908

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Propionyl-CoA carboxylase beta chain, mitochondrial1 Publication (EC:6.4.1.31 Publication)
    Short name:
    PCCase subunit beta
    Alternative name(s):
    Propanoyl-CoA:carbon dioxide ligase subunit beta
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:PCCBBy similarity
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13
    • UP000008227 Componenti: Unplaced

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Mitochondrion

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 28MitochondrionBy similarityAdd BLAST28
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000029529 – 539Propionyl-CoA carboxylase beta chain, mitochondrialAdd BLAST511

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei71PhosphoserineBy similarity1
    Modified residuei99N6-acetyllysine; alternateBy similarity1
    Modified residuei99N6-succinyllysine; alternateBy similarity1
    Modified residuei474N6-acetyllysine; alternateBy similarity1
    Modified residuei474N6-succinyllysine; alternateBy similarity1
    Modified residuei489N6-acetyllysine; alternateBy similarity1
    Modified residuei489N6-succinyllysine; alternateBy similarity1

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P79384

    PeptideAtlas

    More...
    PeptideAtlasi
    P79384

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P79384

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSSSCG00000011653, Expressed in adult mammalian kidney and 36 other tissues

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    P79384, baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    P79384, SS

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    The holoenzyme is a dodecamer composed of 6 PCCA/alpha subunits and 6 PCCB/beta subunits.

    By similarity

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    9823.ENSSSCP00000012423

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    P79384

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini32 – 290CoA carboxyltransferase N-terminalPROSITE-ProRule annotationAdd BLAST259
    Domaini294 – 533CoA carboxyltransferase C-terminalPROSITE-ProRule annotationAdd BLAST240

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni32 – 533CarboxyltransferasePROSITE-ProRule annotationAdd BLAST502
    Regioni325 – 358Acyl-CoA bindingSequence analysisAdd BLAST34

    <p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    The beta subunit contains the carboxyl transferase (CT) domain.By similarity

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the AccD/PCCB family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0540, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_018822_6_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P79384

    KEGG Orthology (KO)

    More...
    KOi
    K01966

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    CHFSVMA

    Database of Orthologous Groups

    More...
    OrthoDBi
    402617at2759

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF314350

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR034733, AcCoA_carboxyl
    IPR029045, ClpP/crotonase-like_dom_sf
    IPR011763, COA_CT_C
    IPR011762, COA_CT_N

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01039, Carboxyl_trans, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF52096, SSF52096, 2 hits

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS50989, COA_CT_CTER, 1 hit
    PS50980, COA_CT_NTER, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    P79384-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MAAAVRVTAA RARLRVVVRS LHAGVRSLCT QPVSVNERIE NKRQAALLGG
    60 70 80 90 100
    GQRRIDSQHK RGKLTARERI SLLLDPGSFI ESDMFVEHRC ADFGMAADKN
    110 120 130 140 150
    KFPGDSVVTG RGRINGRLVY VFSQDFTVFG GSLSGAHAQK ICKIMDQAMT
    160 170 180 190 200
    VGAPVIGLND SGGARIQEGV ESLAGYADIF LRNVSASGVI PQISLIMGPC
    210 220 230 240 250
    AGGAVYSPAL TDFTFMVKDT SYLFITGPDV VKSVTNEDVT QEELGGARTH
    260 270 280 290 300
    TTMSGVAHRA FDNDVDALCN LREFFNYLPL SNQDPAPIRE CHDPSDRLVP
    310 320 330 340 350
    ELDTVVPLES TRAYDMVDII YSIVDERDFF EIMPNYAKNI IVGFARMNGR
    360 370 380 390 400
    TVGIVGNQPK VASGCLDINS SVKGARFVRF CDAFNIPLIT FVDVPGFLPG
    410 420 430 440 450
    TAQEYGGIIR HGAKLLYAFA EATVPKITVI TRKAYGGAYD VMSSKHLCGD
    460 470 480 490 500
    TNYAWPTAEI AVMGAKGAVE IIFKGHENVE AAQAEYIEKF ANPFPAAVRG
    510 520 530
    FVDDIIQPSS TRARICCDLD VLASKKVQRP WRKHANIPL
    Length:539
    Mass (Da):58,590
    Last modified:May 1, 1997 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i756014F5C357E9DB
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AB000886 mRNA Translation: BAA19203.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_999066.1, NM_213901.1

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENSSSCT00040056794; ENSSSCP00040023610; ENSSSCG00040041330
    ENSSSCT00065035648; ENSSSCP00065014918; ENSSSCG00065026480
    ENSSSCT00070021372; ENSSSCP00070017669; ENSSSCG00070010911

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    100158147

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    ssc:100158147

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AB000886 mRNA Translation: BAA19203.1
    RefSeqiNP_999066.1, NM_213901.1

    3D structure databases

    SMRiP79384
    ModBaseiSearch...

    Protein-protein interaction databases

    STRINGi9823.ENSSSCP00000012423

    Proteomic databases

    PaxDbiP79384
    PeptideAtlasiP79384
    PRIDEiP79384

    Genome annotation databases

    EnsembliENSSSCT00040056794; ENSSSCP00040023610; ENSSSCG00040041330
    ENSSSCT00065035648; ENSSSCP00065014918; ENSSSCG00065026480
    ENSSSCT00070021372; ENSSSCP00070017669; ENSSSCG00070010911
    GeneIDi100158147
    KEGGissc:100158147

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    5096

    Phylogenomic databases

    eggNOGiKOG0540, Eukaryota
    HOGENOMiCLU_018822_6_0_1
    InParanoidiP79384
    KOiK01966
    OMAiCHFSVMA
    OrthoDBi402617at2759
    TreeFamiTF314350

    Enzyme and pathway databases

    UniPathwayiUPA00945;UER00908
    ReactomeiR-SSC-196780, Biotin transport and metabolism
    R-SSC-71032, Propionyl-CoA catabolism

    Gene expression databases

    BgeeiENSSSCG00000011653, Expressed in adult mammalian kidney and 36 other tissues
    ExpressionAtlasiP79384, baseline and differential
    GenevisibleiP79384, SS

    Family and domain databases

    InterProiView protein in InterPro
    IPR034733, AcCoA_carboxyl
    IPR029045, ClpP/crotonase-like_dom_sf
    IPR011763, COA_CT_C
    IPR011762, COA_CT_N
    PfamiView protein in Pfam
    PF01039, Carboxyl_trans, 1 hit
    SUPFAMiSSF52096, SSF52096, 2 hits
    PROSITEiView protein in PROSITE
    PS50989, COA_CT_CTER, 1 hit
    PS50980, COA_CT_NTER, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPCCB_PIG
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P79384
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
    Last sequence update: May 1, 1997
    Last modified: August 12, 2020
    This is version 122 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
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