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Protein

Division mal foutue 1 protein

Gene

mid1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

At the onset of mitosis, forms a medial ring structure before the arrangement of the medial actin ring. Essential for the central positioning of the division septum before the cell divides.2 Publications

GO - Molecular functioni

  • polo box domain specific binding Source: PomBase

GO - Biological processi

  • cellular protein localization Source: PomBase
  • establishment of mitotic actomyosin contractile ring localization Source: PomBase
  • mitotic actomyosin contractile ring assembly Source: PomBase
  • mitotic cytokinesis Source: PomBase
  • mitotic cytokinesis, site selection Source: PomBase
  • protein localization to mitotic actomyosin contractile ring Source: PomBase
  • regulation of mitotic actomyosin contractile ring maintenance Source: PomBase
  • septin ring organization Source: PomBase

Keywordsi

Biological processCell cycle, Cell division, Mitosis

Names & Taxonomyi

Protein namesi
Recommended name:
Division mal foutue 1 protein
Gene namesi
Name:mid1
Synonyms:dmf1
ORF Names:SPCC4B3.15
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC4B3.15
PomBaseiSPCC4B3.15 mid1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000799371 – 920Division mal foutue 1 proteinAdd BLAST920

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei531Phosphoserine1 Publication1

Post-translational modificationi

Phosphorylated. Becomes hyperphosphorylated when located at the medial ring.2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP78953
PaxDbiP78953
PRIDEiP78953

PTM databases

iPTMnetiP78953

Interactioni

Subunit structurei

Interacts with blt1 and cdr2.1 Publication

GO - Molecular functioni

  • polo box domain specific binding Source: PomBase

Protein-protein interaction databases

BioGridi275775, 202 interactors
DIPiDIP-36604N
IntActiP78953, 3 interactors
STRINGi4896.SPCC4B3.15.1

Structurei

Secondary structure

1920
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi81 – 93Combined sources13
Beta strandi605 – 611Combined sources7
Beta strandi614 – 620Combined sources7
Beta strandi628 – 638Combined sources11
Beta strandi642 – 652Combined sources11
Beta strandi714 – 723Combined sources10
Helixi724 – 726Combined sources3
Helixi728 – 731Combined sources4
Beta strandi736 – 744Combined sources9
Beta strandi762 – 774Combined sources13
Helixi780 – 782Combined sources3
Helixi787 – 794Combined sources8
Beta strandi797 – 799Combined sources3
Beta strandi803 – 810Combined sources8
Beta strandi818 – 824Combined sources7
Beta strandi827 – 832Combined sources6
Turni833 – 836Combined sources4
Beta strandi837 – 844Combined sources8
Beta strandi846 – 848Combined sources3
Helixi860 – 863Combined sources4
Beta strandi867 – 873Combined sources7
Beta strandi878 – 884Combined sources7
Helixi886 – 896Combined sources11
Beta strandi901 – 903Combined sources3
Helixi910 – 918Combined sources9

3D structure databases

SMRiP78953
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini802 – 901PHPROSITE-ProRule annotationAdd BLAST100

Phylogenomic databases

OrthoDBiEOG092C0ZH1

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
SMARTiView protein in SMART
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

P78953-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEQEFSYRE AKDVSLDSKG LENSFLSSPN REKTPLFFEG NSNETSGYDQ
60 70 80 90 100
TKNFTHGDGD MSLGNLSELN VATDLLESLD LRSMYMHGYG HLDSSFSSQH
110 120 130 140 150
SPDNRKRMSS TSVFKRINSE EEGRIPSLTY SAGTMNSTSS STASLKGADI
160 170 180 190 200
VADYETFNPD QNLAELSFDR SKSSRKRAVE VAEFSRAKTM SPLEYTVQHP
210 220 230 240 250
YQSHNELSTN PARARAGSVP NLARIPSDVK PVPPAHLSAS STVGPRILPS
260 270 280 290 300
LPKDTTEDNP ALERVETTAS LDMDYKPLEP LAPIQEAPVE DTSEPFSSVP
310 320 330 340 350
EATLDDSDIS TESLRKKVLA KMEAKRISSG SSYASTLRKV YDFSELSLPT
360 370 380 390 400
NGKDYDELYL QSSRNSEPEI STIINDSLQQ ENMDEDISAT SIPKSQAAYG
410 420 430 440 450
HGSVTYHEVP RYNLTSASVG YSISSQRGRI KSSSTIDNLS AILSSEDLRH
460 470 480 490 500
PSMQPVPGTK RTYSNYCENE PNKSSQSLVS SESHNVEGWN YSETGTVGFY
510 520 530 540 550
DPSAEISASI DELRQSTPVA RDSELLSRAH SFDLNRLDLP SQDKSTSYEV
560 570 580 590 600
PNGTENQSPR PVTSLGFVNE TFFEEKPKAP LPLGRFYIHL NSILNISISE
610 620 630 640 650
VHSPIKIIVN TPTQNMQLPW QAVNGNNRLD HDFAFHVDDN FKVSFMFLDI
660 670 680 690 700
PIEDKSNGSK GVSATKDVSN GKPAETKSKA RKFFDKLFNR RKKRKLNKAA
710 720 730 740 750
AVENSKAKKS VVIKKVSGTA TLNLGNVKDS CFGKAFNVEI PIISRGFLEA
760 770 780 790 800
IPVKINSIGK RTLGNLTLTC LYIPELSVPE QELPFTLEQA TMDLRHVRSN
810 820 830 840 850
YLYNEGYLYR LEDSSIRRRF VVLRSKQLNF YAEKGGQYLD TFQLSKTVVS
860 870 880 890 900
IPMVNFSEAV SNLGLVAGIL ATSVDRRHVQ LFADSKKVCQ KWLQVMNSRS
910 920
FALDRGTEKL WLQEYVNFMA
Length:920
Mass (Da):102,367
Last modified:May 1, 1997 - v1
Checksum:iCA95FB48A20549B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07599 mRNA Translation: CAA68873.1
CU329672 Genomic DNA Translation: CAB60689.1
PIRiT43263
RefSeqiNP_588075.1, NM_001023067.2

Genome annotation databases

EnsemblFungiiSPCC4B3.15.1; SPCC4B3.15.1:pep; SPCC4B3.15
GeneIDi2539205
KEGGispo:SPCC4B3.15

Entry informationi

Entry nameiMID1_SCHPO
AccessioniPrimary (citable) accession number: P78953
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: May 1, 1997
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

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