High-affinity glucose transporter ght5

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• carbohydrate:proton symporter activity Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• fructose transmembrane transporter activity Source: PomBase <p>Inferred from Genetic Interaction</p> <p>Used to describe "traditional" genetic interactions such as suppressors and synthetic lethals as well as other techniques such as functional complementation, rescue experiments, or inferences about a gene drawn from the phenotype of a mutation in a different gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#igi">GO evidence code guide</a></p> Inferred from genetic interactionⁱ
  • Ref.1

    "Multiple hexose transporters of Schizosaccharomyces pombe."
    Heiland S., Radovanovic N., Hoefer M., Winderickx J., Lichtenberg H.
    J. Bacteriol. 182:2153-2162(2000) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION.
• glucose transmembrane transporter activity Source: PomBaseInferred from genetic interactionⁱ
  • Ref.1

    "Multiple hexose transporters of Schizosaccharomyces pombe."
    Heiland S., Radovanovic N., Hoefer M., Winderickx J., Lichtenberg H.
    J. Bacteriol. 182:2153-2162(2000) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION.
• high-affinity glucose transmembrane transporter activity Source: PomBase <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • "Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR."
    Saitoh S., Mori A., Uehara L., Masuda F., Soejima S., Yanagida M.
    Mol Biol Cell 26:373-386(2015) [PubMed] [Europe PMC] [Abstract]

GO - Biological processⁱ

• carbohydrate transport Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• fructose import across plasma membrane Source: PomBaseInferred from genetic interactionⁱ
  • Ref.1

    "Multiple hexose transporters of Schizosaccharomyces pombe."
    Heiland S., Radovanovic N., Hoefer M., Winderickx J., Lichtenberg H.
    J. Bacteriol. 182:2153-2162(2000) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION.
• glucose import across plasma membrane Source: PomBaseInferred from mutant phenotypeⁱ
  • "Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR."
    Saitoh S., Mori A., Uehara L., Masuda F., Soejima S., Yanagida M.
    Mol Biol Cell 26:373-386(2015) [PubMed] [Europe PMC] [Abstract]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

• UniProt annotation
• GO - Cellular component

Topology

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Region

Compositional bias

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MGKNLTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDS 
        60         70         80         90        100
YSYSSARQGL ITGMVNVGSF FGCFLSSPLM DRIGKRTSIM FWTIVYLIGI 
       110        120        130        140        150
ILQVTAVPSW VQIMVAKIWT GLSIGALSVL APGFQSEVAP ADLRGTIVTT 
       160        170        180        190        200
YQLAVTGGIF IAACINMGTH KLHKTAQWRV SMGINLLWGI ITFIGISFLP 
       210        220        230        240        250
ESPRYLISVG RDEEALQIMA KNNDLPIEHE VIQTEYHVIK SDCEAELAGG 
       260        270        280        290        300
PATWPEIFGP DIRYRTFLGL GVMSLQQLTG DNYYFYYGFE VFEGTGMNSP 
       310        320        330        340        350
YLSALILDAV NFGCTFGGLF VLEFFGRRMP LIIGALWQSI TFFIYAAVGN 
       360        370        380        390        400
RALTRKNGTS NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR 
       410        420        430        440        450
SKCAAVATTG NWLWGFLISF FTPFITNSIG FKYGYIFAAC NLCAACIIFL 
       460        470        480        490        500
FAHETKGLTL EEINELYISG AKPWMPRPKN LGNFTKQQEE VREKSRGVQG 
       510        520        530        540 
ESAAHLENVD GEEGIEDSSN DISSTTSSDG RAKPESSYHD QEEQFA     

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. Schizosaccharomyces pombe
   Schizosaccharomyces pombe: entries and gene names
2. SIMILARITY comments
   Index of protein domains and families