We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P78831 (GHT5_SCHPO)
Protein
High-affinity glucose transporter ght5
Gene
ght5
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
High-affinity glucose transporter.
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
- fructose transmembrane transporter activity Source: PomBase
- glucose transmembrane transporter activity Source: PomBase
- high-affinity glucose transmembrane transporter activity Source: PomBase
GO - Biological processi
- carbohydrate transport Source: GO_Central
- fructose import across plasma membrane Source: PomBase
- glucose import across plasma membrane Source: PomBase
Keywordsi
Biological process | Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: High-affinity glucose transporter ght5Alternative name(s): Hexose transporter 5 |
Gene namesi | Name:ght5 ORF Names:SPCC1235.14 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPCC1235.14, ght5 |
VEuPathDBi | FungiDB:SPCC1235.14 |
Subcellular locationi
Other locations
Plasma Membrane
- integral component of plasma membrane Source: PomBase
- plasma membrane Source: PomBase
- plasma membrane of cell tip Source: PomBase
Vacuole
- fungal-type vacuole lumen Source: PomBase
Other locations
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 9 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 10 – 30 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 31 – 58 | ExtracellularSequence analysisAdd BLAST | 28 | |
Transmembranei | 59 – 79 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 80 – 87 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 88 – 108 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 109 – 112 | ExtracellularSequence analysis | 4 | |
Transmembranei | 113 – 133 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 134 – 144 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 145 – 165 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 166 – 179 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 180 – 200 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 201 – 266 | CytoplasmicSequence analysisAdd BLAST | 66 | |
Transmembranei | 267 – 285 | Helical; Name=7Sequence analysisAdd BLAST | 19 | |
Topological domaini | 286 – 301 | ExtracellularSequence analysisAdd BLAST | 16 | |
Transmembranei | 302 – 322 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 323 – 328 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 329 – 349 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 350 – 363 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 364 – 384 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 385 – 404 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 405 – 425 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 426 – 432 | ExtracellularSequence analysis | 7 | |
Transmembranei | 433 – 453 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 454 – 546 | CytoplasmicSequence analysisAdd BLAST | 93 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050413 | 1 – 546 | High-affinity glucose transporter ght5Add BLAST | 546 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 357 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 528 | Phosphoserine1 Publication | 1 | |
Modified residuei | 537 | Phosphoserine1 Publication | 1 |
Keywords - PTMi
Glycoprotein, PhosphoproteinProteomic databases
MaxQBi | P78831 |
PaxDbi | P78831 |
PTM databases
iPTMneti | P78831 |
SwissPalmi | P78831 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 275810, 2 interactors |
STRINGi | 4896.SPCC1235.14.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 486 – 546 | DisorderedSequence analysisAdd BLAST | 61 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 486 – 512 | Basic and acidic residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 518 – 532 | Polar residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | P78831 |
OMAi | SFFTRFI |
PhylomeDBi | P78831 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P78831-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKNLTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDS
60 70 80 90 100
YSYSSARQGL ITGMVNVGSF FGCFLSSPLM DRIGKRTSIM FWTIVYLIGI
110 120 130 140 150
ILQVTAVPSW VQIMVAKIWT GLSIGALSVL APGFQSEVAP ADLRGTIVTT
160 170 180 190 200
YQLAVTGGIF IAACINMGTH KLHKTAQWRV SMGINLLWGI ITFIGISFLP
210 220 230 240 250
ESPRYLISVG RDEEALQIMA KNNDLPIEHE VIQTEYHVIK SDCEAELAGG
260 270 280 290 300
PATWPEIFGP DIRYRTFLGL GVMSLQQLTG DNYYFYYGFE VFEGTGMNSP
310 320 330 340 350
YLSALILDAV NFGCTFGGLF VLEFFGRRMP LIIGALWQSI TFFIYAAVGN
360 370 380 390 400
RALTRKNGTS NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR
410 420 430 440 450
SKCAAVATTG NWLWGFLISF FTPFITNSIG FKYGYIFAAC NLCAACIIFL
460 470 480 490 500
FAHETKGLTL EEINELYISG AKPWMPRPKN LGNFTKQQEE VREKSRGVQG
510 520 530 540
ESAAHLENVD GEEGIEDSSN DISSTTSSDG RAKPESSYHD QEEQFA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF051141 mRNA Translation: AAC63977.1 CU329672 Genomic DNA Translation: CAA21118.1 D89179 mRNA Translation: BAA13841.1 |
PIRi | T40888 T42623 |
RefSeqi | NP_587740.1, NM_001022735.2 |
Genome annotation databases
EnsemblFungii | SPCC1235.14.1; SPCC1235.14.1:pep; SPCC1235.14 |
GeneIDi | 2539240 |
KEGGi | spo:SPCC1235.14 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF051141 mRNA Translation: AAC63977.1 CU329672 Genomic DNA Translation: CAA21118.1 D89179 mRNA Translation: BAA13841.1 |
PIRi | T40888 T42623 |
RefSeqi | NP_587740.1, NM_001022735.2 |
3D structure databases
SMRi | P78831 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 275810, 2 interactors |
STRINGi | 4896.SPCC1235.14.1 |
PTM databases
iPTMneti | P78831 |
SwissPalmi | P78831 |
Proteomic databases
MaxQBi | P78831 |
PaxDbi | P78831 |
Genome annotation databases
EnsemblFungii | SPCC1235.14.1; SPCC1235.14.1:pep; SPCC1235.14 |
GeneIDi | 2539240 |
KEGGi | spo:SPCC1235.14 |
Organism-specific databases
PomBasei | SPCC1235.14, ght5 |
VEuPathDBi | FungiDB:SPCC1235.14 |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | P78831 |
OMAi | SFFTRFI |
PhylomeDBi | P78831 |
Miscellaneous databases
PROi | PR:P78831 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GHT5_SCHPO | |
Accessioni | P78831Primary (citable) accession number: P78831 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2001 |
Last sequence update: | November 1, 1998 | |
Last modified: | February 23, 2022 | |
This is version 149 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families