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1 to 25 of 921  Show
  1. 1
    "5' cDNA sequence RelA isolated from Human umbilical vein endothelial cells."
    Remacle J.E., Brys R., Pype S., Nelles L., Huylebroeck D.
    Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Tissue: Umbilical vein.
    Source: UniProtKB/TrEMBL (unreviewed).
  2. 2
    "Physical exercise induces activation of NF-kappaB in human peripheral blood lymphocytes."
    Vider J., Laaksonen D.E., Kilk A., Atalay M., Lehtmaa J., Zilmer M., Sen C.K.
    Antioxid Redox Signal 3:1131-1137(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Physical exercise induces activation of NF-kappaB in human peripheral blood lymphocytes.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  3. 3
    "Respiratory syncytial virus and TNF alpha induction of chemokine gene expression involves differential activation of Rel A and NF-kappa B1."
    Carpenter L.R., Moy J.N., Roebuck K.A.
    BMC Infect Dis 2:5-5(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Respiratory syncytial virus induction of chemokine gene expression involves a redox-sensitive NF-kappaB1 signaling mechanism that differs from that mediated by TNF alpha in that it involves predominantly the RelA subunit of NF-kappaB.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  4. 4
    "[Activation of nuclear factor-kappaB and effects of anti-inflammatory treatment thereon in intestinal mucosa of patients with ulcerative colitis]."
    Gan H., Ouyang Q., Chen Y., Xia Q.
    Zhonghua Yi Xue Za Zhi 82:384-388(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: activation and expression of nuclear factor-kappaB (NF-kappaB) and effects of anti-inflammatory treatment on NF-kappaB in the intestinal mucosa of patients with ulcerative colitis (UC).
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  5. 5
    "MDM2 induces NF-kappaB/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia."
    Gu L., Findley H.W., Zhou M.
    Blood 99:3367-3375(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: MDM2 can induce expression of the p65 subunit of NF-kappaB.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  6. 6
    "[The Rel/NF-kappa-B transcription factors: complex role in cell regulation]."
    Bottex-Gauthier C., Pollet S., Favier A., Vidal D.R.
    Pathol Biol (Paris) 50:204-211(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: NF-KB could be considered as a coordinating element in the body's response to stress infection or inflammation and it may be a good therapeutic target.
    Source: GeneRIF:5970.

    This publication is mapped to 10 other entries.

  7. 7
    "A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc."
    Chapman N.R., Webster G.A., Gillespie P.J., Wilson B.J., Crouch D.H., Perkins N.D.
    Biochem J 366:459-469(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: A novel form is induced by and forms a complex with the proto-oncogene c-Myc.
    Source: GeneRIF:5970.

    This publication is mapped to 69 other entries.

  8. 8
    "Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780)."
    Gu Z., Lee R.Y., Skaar T.C., Bouker K.B., Welch J.N., Lu J., Liu A., Zhu Y., Davis N., Leonessa F., Brunner N., Wang Y., Clarke R.
    Cancer Res 62:3428-3437(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: NFkB is associated with antiestrogen resistance in breast cancer.
    Source: GeneRIF:5970.

    This publication is mapped to 26 other entries.

  9. 9
    "The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD."
    Bernard D., Monte D., Vandenbunder B., Abbadie C.
    Oncogene 21:4392-4402(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: C-Rel can both induce and inhibit apoptosis in HeLa cells by upregulation of MnSOD.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  10. 10
    "Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo."
    Nishi T., Shimizu N., Hiramoto M., Sato I., Yamaguchi Y., Hasegawa M., Aizawa S., Tanaka H., Kataoka K., Watanabe H., Handa H.
    J Biol Chem 277:44548-44556(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: NF-kappaB is regulated by the redox factor Ref-1 in the nucleus.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  11. 11
    "Regulation of nuclear translocation of nuclear factor-kappaB relA: evidence for complex dynamics at the single-cell level."
    Schooley K., Zhu P., Dower S.K., Qwarnstrom E.E.
    Biochem J 369:331-339(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location.
    Annotation: Data show that interleukin-1 induces nuclear transport of RelA.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  12. 12
    "FcgammaR cross-linking mediates NF-kappaB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development."
    Drechsler Y., Chavan S., Catalano D., Mandrekar P., Szabo G.
    J Leukoc Biol 72:657-667(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: cross-linking FcgammaRI and -RII but not FcgammaRIII activates transcription factor NF-kappaB(p65).
    Source: GeneRIF:5970.

    This publication is mapped to 9 other entries.

  13. 13
    "Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65."
    Kiernan R., Bres V., Ng R.W., Coudart M.-P., El Messaoudi S., Sardet C., Jin D.-Y., Emiliani S., Benkirane M.
    J. Biol. Chem. 278:2758-2766(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing, Interaction.
    Annotation: acetylation of p65 plays a key role in IkappaBetaalpha-mediated attenuation of NF-kappaBeta transcriptional activity which is an important process that restores the latent state in post-induced cells.
    Source: GeneRIF:5970.

    This publication is mapped to 13 other entries.

  14. 14
    "The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536."
    Jiang X., Takahashi N., Matsui N., Tetsuka T., Okamoto T.
    J Biol Chem 278:919-926(2003) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536.
    Source: GeneRIF:5970.

    This publication is mapped to 11 other entries.

  15. 15
    "B-oligomer of pertussis toxin inhibits HIV-1 LTR-driven transcription through suppression of NF-kappaB p65 subunit activity."
    Iordanskiy S., Iordanskaya T., Quivy V., Van Lint C., Bukrinsky M.
    Virology 302:195-206(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: B-oligomer of pertussis toxin inhibits HIV-1 LTR-driven transcription through suppression of NF-kappaB p65 subunit activity.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  16. 16
    "Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta-NF-kappa B and PKC-zeta-GATA signaling pathways."
    Minami T., Abid M.R., Zhang J., King G., Kodama T., Aird W.C.
    J Biol Chem 278:6976-6984(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Protein kinase C delta-NF-kappaB signaling regulates VCAM1 stimulation by thrombin in endothelial cells.
    Source: GeneRIF:5970.

    This publication is mapped to 22 other entries.

  17. 17
    "Regulation of RelA (p65) function by the large subunit of replication factor C."
    Anderson L.A., Perkins N.D.
    Mol Cell Biol 23:721-732(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: RelA expression is regulated by replication factor C (p140).
    Source: GeneRIF:5970.

    This publication is mapped to 10 other entries.

  18. 18
    "Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein."
    Akiyama M., Hideshima T., Hayashi T., Tai Y.T., Mitsiades C.S., Mitsiades N., Chauhan D., Richardson P., Munshi N.C., Anderson K.C.
    Cancer Res 63:18-21(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  19. 19
    "Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses."
    Okazaki T., Sakon S., Sasazuki T., Sakurai H., Doi T., Yagita H., Okumura K., Nakano H.
    Biochem Biophys Res Commun 300:807-812(2003) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: S276 is the major phosphorylation site of p65 and its phosphorylation is essential for p65-dependent cellular responses.
    Source: GeneRIF:5970.

    This publication is mapped to 9 other entries.

  20. 20
    "IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways."
    Espinosa L., Ingles-Esteve J., Robert-Moreno A., Bigas A.
    Mol Biol Cell 14:491-502(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: IkappaBalpha and p65 have roles in regulating the cytoplasmic shuttling of nuclear corepressors.
    Source: GeneRIF:5970.

    This publication is mapped to 21 other entries.

  21. 21
    "Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer."
    Wong B.C., Jiang X.h., Fan X.M., Lin M.C., Jiang S.H., Lam S.K., Kung H.F.
    Oncogene 22:1189-1197(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The translocation of RelA/p65 was investigated using Western blotting and immunocytochemistry. the COX-2 inhibitor SC236 worked directly through suppressing nuclear translocation of RelA/p65.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  22. 22
    "Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types."
    Majumdar S., Aggarwal B.B.
    Oncogene 22:1206-1218(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Adenosine selectively suppresses TNF-induced NF-kappaB activation which may contribute to its role in suppression of inflammation and of the immune system.
    Source: GeneRIF:5970.

    This publication is mapped to 18 other entries.

  23. 23
    "Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis."
    Fujioka S., Sclabas G.M., Schmidt C., Niu J., Frederick W.A., Dong Q.G., Abbruzzese J.L., Evans D.B., Baker C., Chiao P.J.
    Oncogene 22:1365-1370(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Inhibiting constitutive NF-kappa B activity by expressing I kappa B alpha M suppressed the tumorigenicity of a nonmetastatic human pancreatic cancer cell line PANC-1 in an orthotopic nude mouse model.
    Source: GeneRIF:5970.

    This publication is mapped to 8 other entries.

  24. 24
    "The effects of labour and of interleukin 1 beta upon the expression of nuclear factor kappa B related proteins in human amnion."
    Lee Y., Allport V., Sykes A., Lindstrom T., Slater D., Bennett P.
    Mol Hum Reprod 9:213-218(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: Data show that increased expression of nuclear factor-kappaB (NF-kB) in amnion during labor is associated with an increase in the expression of NF-kBp65 and the NF-kB binding proteins IkBa IkBb-1 and IkBb-2.
    Source: GeneRIF:5970.

    This publication is mapped to 14 other entries.

  25. 25
    "Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin."
    Hinata K., Gervin A.M., Jennifer Zhang Y., Khavari P.A.
    Oncogene 22:1955-1964(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: NF-kappa B induced proinflammatory & antiapoptotic genes in epithelial and mesenchymal cells of human skin. In keratinocytes not fibroblasts it induced p21(CIP1). GIF levls increased by NF-kappa B in both but inhibited growth only in keratinocytes.
    Source: GeneRIF:5970.

    This publication is mapped to 10 other entries.

1 to 25 of 921  Show
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