UniProtKB - P78357 (CNTP1_HUMAN)
Contactin-associated protein 1
CNTNAP1
Functioni
Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
3 PublicationsGO - Molecular functioni
- SH3 domain binding Source: BHF-UCL
- signaling receptor activity Source: ProtInc
GO - Biological processi
- axonogenesis Source: Ensembl
- cell adhesion Source: UniProtKB-KW
- central nervous system myelination Source: UniProtKB
- cytoskeleton organization Source: BHF-UCL
- mitochondrion organization Source: Ensembl
- myelination in peripheral nervous system Source: UniProtKB
- neuromuscular junction development, skeletal muscle fiber Source: Ensembl
- neuromuscular process controlling balance Source: Ensembl
- neuromuscular process controlling posture Source: Ensembl
- neuronal action potential propagation Source: BHF-UCL
- neuron projection morphogenesis Source: UniProtKB
- paranodal junction assembly Source: UniProtKB
- paranodal junction maintenance Source: Ensembl
- postsynaptic density organization Source: Ensembl
- protein localization to juxtaparanode region of axon Source: UniProtKB
- protein localization to paranode region of axon Source: BHF-UCL
- signal transduction Source: ProtInc
Keywordsi
Biological process | Cell adhesion |
Enzyme and pathway databases
PathwayCommonsi | P78357 |
Reactomei | R-HSA-447043, Neurofascin interactions |
SignaLinki | P78357 |
Names & Taxonomyi
Protein namesi | Recommended name: Contactin-associated protein 1Short name: Caspr Short name: Caspr1 Alternative name(s): Neurexin IV Neurexin-4 p190 |
Gene namesi | Name:CNTNAP1 Synonyms:CASPR, NRXN4 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:8011, CNTNAP1 |
MIMi | 602346, gene |
neXtProti | NX_P78357 |
VEuPathDBi | HostDB:ENSG00000108797 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type I membrane protein Curated
- paranodal septate junction By similarity
Plasma Membrane
- integral component of plasma membrane Source: ProtInc
- presynaptic active zone membrane Source: Ensembl
Other locations
- integral component of membrane Source: BHF-UCL
- paranodal junction Source: UniProtKB-SubCell
- paranode region of axon Source: BHF-UCL
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 20 – 1283 | ExtracellularSequence analysisAdd BLAST | 1264 | |
Transmembranei | 1284 – 1304 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 1305 – 1384 | CytoplasmicSequence analysisAdd BLAST | 80 |
Keywords - Cellular componenti
Cell junction, MembranePathology & Biotechi
Involvement in diseasei
Lethal congenital contracture syndrome 7 (LCCS7)4 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_078818 | 323 | C → R in LCCS7. 1 PublicationCorresponds to variant dbSNP:rs768554986EnsemblClinVar. | 1 | |
Natural variantiVAR_078820 | 623 – 1384 | Missing in LCCS7 and CHN3. 2 PublicationsAdd BLAST | 762 | |
Natural variantiVAR_078822 | 672 – 1384 | Missing in LCCS7. 1 PublicationAdd BLAST | 713 |
Neuropathy, congenital hypomyelinating, 3 (CHN3)4 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_081766 | 50 | P → Q in CHN3. 1 Publication | 1 | |
Natural variantiVAR_081767 | 212 | L → P in CHN3. 1 PublicationCorresponds to variant dbSNP:rs1567969825EnsemblClinVar. | 1 | |
Natural variantiVAR_078819 | 388 | R → P in CHN3. 1 PublicationCorresponds to variant dbSNP:rs779027563EnsemblClinVar. | 1 | |
Natural variantiVAR_081768 | 559 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 826 | |
Natural variantiVAR_081769 | 621 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 764 | |
Natural variantiVAR_078820 | 623 – 1384 | Missing in LCCS7 and CHN3. 2 PublicationsAdd BLAST | 762 | |
Natural variantiVAR_078821 | 671 – 1384 | Missing in CHN3. 2 PublicationsAdd BLAST | 714 | |
Natural variantiVAR_081770 | 714 | R → P in CHN3. 1 Publication | 1 | |
Natural variantiVAR_078823 | 764 | R → C in CHN3. 2 PublicationsCorresponds to variant dbSNP:rs761805324EnsemblClinVar. | 1 | |
Natural variantiVAR_081771 | 782 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 603 | |
Natural variantiVAR_081772 | 896 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 489 |
Keywords - Diseasei
Disease variant, NeuropathyOrganism-specific databases
DisGeNETi | 8506 |
GeneReviewsi | CNTNAP1 |
MalaCardsi | CNTNAP1 |
MIMi | 616286, phenotype 618186, phenotype |
OpenTargetsi | ENSG00000108797 |
Orphaneti | 2680, Hypomyelination neuropathy-arthrogryposis syndrome |
PharmGKBi | PA26691 |
Miscellaneous databases
Pharosi | P78357, Tbio |
Genetic variation databases
BioMutai | CNTNAP1 |
DMDMi | 17433016 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000019503 | 20 – 1384 | Contactin-associated protein 1Add BLAST | 1365 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 25 ↔ 168 | By similarity | ||
Glycosylationi | 120 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 128 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 276 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 323 ↔ 355 | By similarity | ||
Glycosylationi | 420 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 499 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 506 ↔ 538 | By similarity | ||
Glycosylationi | 518 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 544 ↔ 555 | By similarity | ||
Disulfide bondi | 549 ↔ 564 | By similarity | ||
Disulfide bondi | 566 ↔ 576 | By similarity | ||
Glycosylationi | 597 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 653 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 664 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 763 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 804 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 843 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 860 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 930 ↔ 957 | By similarity | ||
Glycosylationi | 948 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 956 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 961 ↔ 974 | By similarity | ||
Disulfide bondi | 968 ↔ 983 | By similarity | ||
Disulfide bondi | 985 ↔ 995 | By similarity | ||
Glycosylationi | 1078 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 1147 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 1209 ↔ 1250 | By similarity | ||
Modified residuei | 1383 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
EPDi | P78357 |
jPOSTi | P78357 |
MassIVEi | P78357 |
MaxQBi | P78357 |
PaxDbi | P78357 |
PeptideAtlasi | P78357 |
PRIDEi | P78357 |
ProteomicsDBi | 57588 |
PTM databases
GlyGeni | P78357, 17 sites |
iPTMneti | P78357 |
PhosphoSitePlusi | P78357 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000108797, Expressed in frontal cortex and 184 other tissues |
ExpressionAtlasi | P78357, baseline and differential |
Genevisiblei | P78357, HS |
Organism-specific databases
HPAi | ENSG00000108797, Tissue enhanced (brain) |
Interactioni
Subunit structurei
Interacts with CNTN1/contactin in cis form.
1 PublicationBinary interactionsi
P78357
With | #Exp. | IntAct |
---|---|---|
NCK1 [P16333] | 2 | EBI-1751903,EBI-389883 |
GO - Molecular functioni
- SH3 domain binding Source: BHF-UCL
Protein-protein interaction databases
BioGRIDi | 114078, 99 interactors |
CORUMi | P78357 |
IntActi | P78357, 22 interactors |
MINTi | P78357 |
STRINGi | 9606.ENSP00000264638 |
Miscellaneous databases
RNActi | P78357, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 25 – 168 | F5/8 type CPROSITE-ProRule annotationAdd BLAST | 144 | |
Domaini | 203 – 355 | Laminin G-like 1PROSITE-ProRule annotationAdd BLAST | 153 | |
Domaini | 389 – 538 | Laminin G-like 2PROSITE-ProRule annotationAdd BLAST | 150 | |
Domaini | 540 – 577 | EGF-like 1PROSITE-ProRule annotationAdd BLAST | 38 | |
Domaini | 576 – 795 | Fibrinogen C-terminalPROSITE-ProRule annotationAdd BLAST | 220 | |
Domaini | 813 – 956 | Laminin G-like 3PROSITE-ProRule annotationAdd BLAST | 144 | |
Domaini | 957 – 996 | EGF-like 2PROSITE-ProRule annotationAdd BLAST | 40 | |
Domaini | 1088 – 1250 | Laminin G-like 4PROSITE-ProRule annotationAdd BLAST | 163 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1319 – 1384 | DisorderedSequence analysisAdd BLAST | 66 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 1328 – 1369 | SH3-bindingSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1350 – 1370 | Pro residuesSequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
EGF-like domain, Repeat, SH3-binding, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3516, Eukaryota |
GeneTreei | ENSGT00940000160825 |
HOGENOMi | CLU_003504_1_0_1 |
InParanoidi | P78357 |
OMAi | HCAHPRF |
OrthoDBi | 338397at2759 |
PhylomeDBi | P78357 |
TreeFami | TF321823 |
Family and domain databases
CDDi | cd00057, FA58C, 1 hit cd00110, LamG, 4 hits |
InterProi | View protein in InterPro IPR028872, Caspr1 IPR013320, ConA-like_dom_sf IPR000742, EGF-like_dom IPR000421, FA58C IPR036056, Fibrinogen-like_C IPR002181, Fibrinogen_a/b/g_C_dom IPR008979, Galactose-bd-like_sf IPR001791, Laminin_G IPR003585, Neurexin-like |
PANTHERi | PTHR15036:SF43, PTHR15036:SF43, 3 hits |
Pfami | View protein in Pfam PF00754, F5_F8_type_C, 1 hit PF02210, Laminin_G_2, 4 hits |
SMARTi | View protein in SMART SM00294, 4.1m, 1 hit SM00231, FA58C, 1 hit SM00282, LamG, 4 hits |
SUPFAMi | SSF49785, SSF49785, 1 hit SSF49899, SSF49899, 4 hits SSF56496, SSF56496, 1 hit |
PROSITEi | View protein in PROSITE PS50026, EGF_3, 2 hits PS01285, FA58C_1, 1 hit PS01286, FA58C_2, 1 hit PS50022, FA58C_3, 1 hit PS51406, FIBRINOGEN_C_2, 1 hit PS50025, LAM_G_DOMAIN, 4 hits |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MMHLRLFCIL LAAVSGAEGW GYYGCDEELV GPLYARSLGA SSYYSLLTAP
60 70 80 90 100
RFARLHGISG WSPRIGDPNP WLQIDLMKKH RIRAVATQGS FNSWDWVTRY
110 120 130 140 150
MLLYGDRVDS WTPFYQRGHN STFFGNVNES AVVRHDLHFH FTARYIRIVP
160 170 180 190 200
LAWNPRGKIG LRLGLYGCPY KADILYFDGD DAISYRFPRG VSRSLWDVFA
210 220 230 240 250
FSFKTEEKDG LLLHAEGAQG DYVTLELEGA HLLLHMSLGS SPIQPRPGHT
260 270 280 290 300
TVSAGGVLND QHWHYVRVDR FGRDVNFTLD GYVQRFILNG DFERLNLDTE
310 320 330 340 350
MFIGGLVGAA RKNLAYRHNF RGCIENVIFN RVNIADLAVR RHSRITFEGK
360 370 380 390 400
VAFRCLDPVP HPINFGGPHN FVQVPGFPRR GRLAVSFRFR TWDLTGLLLF
410 420 430 440 450
SRLGDGLGHV ELTLSEGQVN VSIAQSGRKK LQFAAGYRLN DGFWHEVNFV
460 470 480 490 500
AQENHAVISI DDVEGAEVRV SYPLLIRTGT SYFFGGCPKP ASRWDCHSNQ
510 520 530 540 550
TAFHGCMELL KVDGQLVNLT LVEGRRLGFY AEVLFDTCGI TDRCSPNMCE
560 570 580 590 600
HDGRCYQSWD DFICYCELTG YKGETCHTPL YKESCEAYRL SGKTSGNFTI
610 620 630 640 650
DPDGSGPLKP FVVYCDIREN RAWTVVRHDR LWTTRVTGSS MERPFLGAIQ
660 670 680 690 700
YWNASWEEVS ALANASQHCE QWIEFSCYNS RLLNTAGGYP YSFWIGRNEE
710 720 730 740 750
QHFYWGGSQP GIQRCACGLD RSCVDPALYC NCDADQPQWR TDKGLLTFVD
760 770 780 790 800
HLPVTQVVIG DTNRSTSEAQ FFLRPLRCYG DRNSWNTISF HTGAALRFPP
810 820 830 840 850
IRANHSLDVS FYFRTSAPSG VFLENMGGPY CQWRRPYVRV ELNTSRDVVF
860 870 880 890 900
AFDVGNGDEN LTVHSDDFEF NDDEWHLVRA EINVKQARLR VDHRPWVLRP
910 920 930 940 950
MPLQTYIWME YDQPLYVGSA ELKRRPFVGC LRAMRLNGVT LNLEGRANAS
960 970 980 990 1000
EGTSPNCTGH CAHPRLPCFH GGRCVERYSY YTCDCDLTAF DGPYCNHDIG
1010 1020 1030 1040 1050
GFFEPGTWMR YNLQSALRSA AREFSHMLSR PVPGYEPGYI PGYDTPGYVP
1060 1070 1080 1090 1100
GYHGPGYRLP DYPRPGRPVP GYRGPVYNVT GEEVSFSFST SSAPAVLLYV
1110 1120 1130 1140 1150
SSFVRDYMAV LIKDDGTLQL RYQLGTSPYV YQLTTRPVTD GQPHSINITR
1160 1170 1180 1190 1200
VYRNLFIQVD YFPLTEQKFS LLVDSQLDSP KALYLGRVME TGVIDPEIQR
1210 1220 1230 1240 1250
YNTPGFSGCL SGVRFNNVAP LKTHFRTPRP MTAELAEALR VQGELSESNC
1260 1270 1280 1290 1300
GAMPRLVSEV PPELDPWYLP PDFPYYHDEG WVAILLGFLV AFLLLGLVGM
1310 1320 1330 1340 1350
LVLFYLQNHR YKGSYHTNEP KAAHEYHPGS KPPLPTSGPA QVPTPTAAPN
1360 1370 1380
QAPASAPAPA PTPAPAPGPR DQNLPQILEE SRSE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketK7EMM9 | K7EMM9_HUMAN | Contactin-associated protein 1 | CNTNAP1 | 740 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_081766 | 50 | P → Q in CHN3. 1 Publication | 1 | |
Natural variantiVAR_081767 | 212 | L → P in CHN3. 1 PublicationCorresponds to variant dbSNP:rs1567969825EnsemblClinVar. | 1 | |
Natural variantiVAR_078818 | 323 | C → R in LCCS7. 1 PublicationCorresponds to variant dbSNP:rs768554986EnsemblClinVar. | 1 | |
Natural variantiVAR_078819 | 388 | R → P in CHN3. 1 PublicationCorresponds to variant dbSNP:rs779027563EnsemblClinVar. | 1 | |
Natural variantiVAR_050267 | 522 | V → L. Corresponds to variant dbSNP:rs35437096Ensembl. | 1 | |
Natural variantiVAR_081768 | 559 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 826 | |
Natural variantiVAR_081769 | 621 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 764 | |
Natural variantiVAR_078820 | 623 – 1384 | Missing in LCCS7 and CHN3. 2 PublicationsAdd BLAST | 762 | |
Natural variantiVAR_078821 | 671 – 1384 | Missing in CHN3. 2 PublicationsAdd BLAST | 714 | |
Natural variantiVAR_078822 | 672 – 1384 | Missing in LCCS7. 1 PublicationAdd BLAST | 713 | |
Natural variantiVAR_081770 | 714 | R → P in CHN3. 1 Publication | 1 | |
Natural variantiVAR_078823 | 764 | R → C in CHN3. 2 PublicationsCorresponds to variant dbSNP:rs761805324EnsemblClinVar. | 1 | |
Natural variantiVAR_081771 | 782 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 603 | |
Natural variantiVAR_081772 | 896 – 1384 | Missing in CHN3. 1 PublicationAdd BLAST | 489 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U87223 mRNA Translation: AAB48481.1 |
CCDSi | CCDS11436.1 |
RefSeqi | NP_003623.1, NM_003632.2 XP_016880727.1, XM_017025238.1 |
Genome annotation databases
Ensembli | ENST00000264638.9; ENSP00000264638.3; ENSG00000108797.12 |
GeneIDi | 8506 |
KEGGi | hsa:8506 |
MANE-Selecti | ENST00000264638.9; ENSP00000264638.3; NM_003632.3; NP_003623.1 |
UCSCi | uc002iay.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U87223 mRNA Translation: AAB48481.1 |
CCDSi | CCDS11436.1 |
RefSeqi | NP_003623.1, NM_003632.2 XP_016880727.1, XM_017025238.1 |
3D structure databases
AlphaFoldDBi | P78357 |
SMRi | P78357 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 114078, 99 interactors |
CORUMi | P78357 |
IntActi | P78357, 22 interactors |
MINTi | P78357 |
STRINGi | 9606.ENSP00000264638 |
PTM databases
GlyGeni | P78357, 17 sites |
iPTMneti | P78357 |
PhosphoSitePlusi | P78357 |
Genetic variation databases
BioMutai | CNTNAP1 |
DMDMi | 17433016 |
Proteomic databases
EPDi | P78357 |
jPOSTi | P78357 |
MassIVEi | P78357 |
MaxQBi | P78357 |
PaxDbi | P78357 |
PeptideAtlasi | P78357 |
PRIDEi | P78357 |
ProteomicsDBi | 57588 |
Protocols and materials databases
ABCDi | P78357, 1 sequenced antibody |
Antibodypediai | 2336, 234 antibodies from 35 providers |
DNASUi | 8506 |
Genome annotation databases
Ensembli | ENST00000264638.9; ENSP00000264638.3; ENSG00000108797.12 |
GeneIDi | 8506 |
KEGGi | hsa:8506 |
MANE-Selecti | ENST00000264638.9; ENSP00000264638.3; NM_003632.3; NP_003623.1 |
UCSCi | uc002iay.4, human |
Organism-specific databases
CTDi | 8506 |
DisGeNETi | 8506 |
GeneCardsi | CNTNAP1 |
GeneReviewsi | CNTNAP1 |
HGNCi | HGNC:8011, CNTNAP1 |
HPAi | ENSG00000108797, Tissue enhanced (brain) |
MalaCardsi | CNTNAP1 |
MIMi | 602346, gene 616286, phenotype 618186, phenotype |
neXtProti | NX_P78357 |
OpenTargetsi | ENSG00000108797 |
Orphaneti | 2680, Hypomyelination neuropathy-arthrogryposis syndrome |
PharmGKBi | PA26691 |
VEuPathDBi | HostDB:ENSG00000108797 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3516, Eukaryota |
GeneTreei | ENSGT00940000160825 |
HOGENOMi | CLU_003504_1_0_1 |
InParanoidi | P78357 |
OMAi | HCAHPRF |
OrthoDBi | 338397at2759 |
PhylomeDBi | P78357 |
TreeFami | TF321823 |
Enzyme and pathway databases
PathwayCommonsi | P78357 |
Reactomei | R-HSA-447043, Neurofascin interactions |
SignaLinki | P78357 |
Miscellaneous databases
BioGRID-ORCSi | 8506, 28 hits in 1082 CRISPR screens |
ChiTaRSi | CNTNAP1, human |
GenomeRNAii | 8506 |
Pharosi | P78357, Tbio |
PROi | PR:P78357 |
RNActi | P78357, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000108797, Expressed in frontal cortex and 184 other tissues |
ExpressionAtlasi | P78357, baseline and differential |
Genevisiblei | P78357, HS |
Family and domain databases
CDDi | cd00057, FA58C, 1 hit cd00110, LamG, 4 hits |
InterProi | View protein in InterPro IPR028872, Caspr1 IPR013320, ConA-like_dom_sf IPR000742, EGF-like_dom IPR000421, FA58C IPR036056, Fibrinogen-like_C IPR002181, Fibrinogen_a/b/g_C_dom IPR008979, Galactose-bd-like_sf IPR001791, Laminin_G IPR003585, Neurexin-like |
PANTHERi | PTHR15036:SF43, PTHR15036:SF43, 3 hits |
Pfami | View protein in Pfam PF00754, F5_F8_type_C, 1 hit PF02210, Laminin_G_2, 4 hits |
SMARTi | View protein in SMART SM00294, 4.1m, 1 hit SM00231, FA58C, 1 hit SM00282, LamG, 4 hits |
SUPFAMi | SSF49785, SSF49785, 1 hit SSF49899, SSF49899, 4 hits SSF56496, SSF56496, 1 hit |
PROSITEi | View protein in PROSITE PS50026, EGF_3, 2 hits PS01285, FA58C_1, 1 hit PS01286, FA58C_2, 1 hit PS50022, FA58C_3, 1 hit PS51406, FIBRINOGEN_C_2, 1 hit PS50025, LAM_G_DOMAIN, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | CNTP1_HUMAN | |
Accessioni | P78357Primary (citable) accession number: P78357 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 5, 2001 |
Last sequence update: | May 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 192 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families