Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable cation-transporting P-type ATPase

Gene

pacL

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could mediate calcium influx.

Catalytic activityi

ATP + H2O = ADP + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3314-aspartylphosphate intermediateBy similarity1
Metal bindingi587MagnesiumBy similarity1
Metal bindingi591MagnesiumBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:G1GJ3-339-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cation-transporting P-type ATPase (EC:3.6.3.-)
Gene namesi
Name:pacL
Ordered Locus Names:MPN_209
ORF Names:MP622
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000808 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 41CytoplasmicSequence analysisAdd BLAST41
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Topological domaini63 – 79ExtracellularSequence analysisAdd BLAST17
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Topological domaini101 – 237CytoplasmicSequence analysisAdd BLAST137
Transmembranei238 – 257HelicalSequence analysisAdd BLAST20
Topological domaini258 – 275ExtracellularSequence analysisAdd BLAST18
Transmembranei276 – 293HelicalSequence analysisAdd BLAST18
Topological domaini294 – 642CytoplasmicSequence analysisAdd BLAST349
Transmembranei643 – 662HelicalSequence analysisAdd BLAST20
Topological domaini663 – 685ExtracellularSequence analysisAdd BLAST23
Transmembranei686 – 706HelicalSequence analysisAdd BLAST21
Topological domaini707 – 724CytoplasmicSequence analysisAdd BLAST18
Transmembranei725 – 747HelicalSequence analysisAdd BLAST23
Topological domaini748 – 768ExtracellularSequence analysisAdd BLAST21
Transmembranei769 – 788HelicalSequence analysisAdd BLAST20
Topological domaini789 – 801CytoplasmicSequence analysisAdd BLAST13
Transmembranei802 – 824HelicalSequence analysisAdd BLAST23
Topological domaini825 – 842ExtracellularSequence analysisAdd BLAST18
Transmembranei843 – 863HelicalSequence analysisAdd BLAST21
Topological domaini864 – 872CytoplasmicSequence analysis9

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000461631 – 872Probable cation-transporting P-type ATPaseAdd BLAST872

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP78036

Interactioni

Protein-protein interaction databases

IntActiP78036, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliP78036
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OMAiCRSESKS

Family and domain databases

Gene3Di3.40.1110.10, 2 hits
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
PF00690 Cation_ATPase_N, 1 hit
PRINTSiPR00120 HATPASE
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

P78036-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKWTGLSAA AVLESRAQHG ANLIPTKKLT PFWLLFLEQF KSLVVILLLV
60 70 80 90 100
ATILSLVVAI ISGVNANWLF DHNLVIEWTQ PFVILITVLA NSLIGSIQEF
110 120 130 140 150
KAQKSAHTLK SLTQPFTRVF REEGLVSLPV GEVVVGDIIF LEAGDIIPAD
160 170 180 190 200
GKVLQANHLR CMESFLTGES VPVDKSVVNT GGKGLLEQTN LLFSGAQVVF
210 220 230 240 250
GSGVFEVTAV GLNTQVGQIV KTVDSSATKL SPLQQKLEKV GKWFSWFGLG
260 270 280 290 300
LFVVVFLVQL GLLGFHNFSA NWSIALIGAI ALVVAIIPEG LVTFINVIFA
310 320 330 340 350
LSVQKLTKQK AIIKYLAAIE TLGGVQIICT DKTGTLTQNK MKVVDYFCFS
360 370 380 390 400
NTTQTDLARA LCLCNNATVN TNGDSTGDPT EIALLQWLDR DGLELNHYTR
410 420 430 440 450
VYEKAFDSNR KLMSVVVQKD NRFIVIVKGA HDVLLPLCKG LDSNQIKPLI
460 470 480 490 500
DERASNGLRN LAVGLKVLYC FDPENTQTVN ELESELDFLG SVSLQDPPRI
510 520 530 540 550
ESKAAIMACH QANITPIMIT GDHLKTATAI AKELGILTDE RQAILGVDLD
560 570 580 590 600
PAKIMEYRVF ARVTPQQKLE IVNAWKQAGY TVAVTGDGVN DAPALVTSDV
610 620 630 640 650
GCCMGQTGVD IAKDAADVII SDDNFATIVN GIEQGRKTFL TCKRVLFNLF
660 670 680 690 700
LTSIAGTIVV LLGLFVLGEV FREQLSKANH NFQVFTPTQL LIINLFVHGF
710 720 730 740 750
PAVALAIQPV QEKLMLKPFS TKNLFYNRGG FDLIWQSLLL SFLTLLFYSL
760 770 780 790 800
GMVYAINDPE LGKSGDLINR AGATCGFMVL GGSAALNSLN LMVDRPLVAT
810 820 830 840 850
NPKHYGIVWL GALSSIFVFL LIIFINPLGL VFSTLKDLTA HPVLIGYSFG
860 870
GVLLYMTINE VVKLIRLSYG SV
Length:872
Mass (Da):94,968
Last modified:February 1, 1997 - v1
Checksum:i42F8001C4798CAFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA Translation: AAB96270.1
PIRiS73948
RefSeqiNP_109897.1, NC_000912.1
WP_010874566.1, NC_000912.1

Genome annotation databases

EnsemblBacteriaiAAB96270; AAB96270; MPN_209
GeneIDi876769
KEGGimpn:MPN209
PATRICifig|272634.6.peg.228

Similar proteinsi

Entry informationi

Entry nameiATCL_MYCPN
AccessioniPrimary (citable) accession number: P78036
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health