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Protein

Probable formate transporter 2

Gene

focB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the bidirectional transport of formate.By similarity

GO - Molecular functioni

  • formate transmembrane transporter activity Source: GO_Central

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:FOCB-MONOMER

Protein family/group databases

TCDBi1.A.16.1.2 the formate-nitrite transporter (fnt) family

Names & Taxonomyi

Protein namesi
Recommended name:
Probable formate transporter 2
Alternative name(s):
Formate channel 2
Gene namesi
Name:focB1 Publication
Ordered Locus Names:b2492, JW2477
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14220 focB

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 35CytoplasmicSequence analysisAdd BLAST35
Transmembranei36 – 56HelicalSequence analysisAdd BLAST21
Topological domaini57 – 68PeriplasmicSequence analysisAdd BLAST12
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Topological domaini90 – 112CytoplasmicSequence analysisAdd BLAST23
Transmembranei113 – 133HelicalSequence analysisAdd BLAST21
Topological domaini134 – 163PeriplasmicSequence analysisAdd BLAST30
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Topological domaini185 – 190CytoplasmicSequence analysis6
Transmembranei191 – 211HelicalSequence analysisAdd BLAST21
Topological domaini212 – 248PeriplasmicSequence analysisAdd BLAST37
Transmembranei249 – 269HelicalSequence analysisAdd BLAST21
Topological domaini270 – 282CytoplasmicSequence analysis1 PublicationAdd BLAST13

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000947211 – 282Probable formate transporter 2Add BLAST282

Proteomic databases

PaxDbiP77733
PRIDEiP77733

Interactioni

Protein-protein interaction databases

BioGridi4261432, 7 interactors
DIPiDIP-9671N
IntActiP77733, 1 interactor
STRINGi316385.ECDH10B_2658

Structurei

3D structure databases

ProteinModelPortaliP77733
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105TMB Bacteria
COG2116 LUCA
HOGENOMiHOG000271393
InParanoidiP77733
KOiK03459
PhylomeDBiP77733

Family and domain databases

Gene3Di1.20.1080.10, 1 hit
InterProiView protein in InterPro
IPR023271 Aquaporin-like
IPR000292 For/NO2_transpt
IPR024002 For/NO2_transpt_CS
PANTHERiPTHR30520 PTHR30520, 1 hit
PfamiView protein in Pfam
PF01226 Form_Nir_trans, 1 hit
TIGRFAMsiTIGR00790 fnt, 1 hit
PROSITEiView protein in PROSITE
PS01005 FORMATE_NITRITE_TP_1, 1 hit
PS01006 FORMATE_NITRITE_TP_2, 1 hit

Sequencei

Sequence statusi: Complete.

P77733-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRNKLSFDLQ LSARKAAIAE RIAAHKIARS KVSVFLMAMS AGVFMAIGFT
60 70 80 90 100
FYLSVIADAP SSQALTHLVG GLCFTLGFIL LAVCGTSLFT SSVMTVMAKS
110 120 130 140 150
RGVISWRTWL INALLVACGN LAGIACFSLL IWFSGLVMSE NAMWGVAVLH
160 170 180 190 200
CAEGKMHHTF TESVSLGIMC NLMVCLALWM SYCGRSLCDK IVAMILPITL
210 220 230 240 250
FVASGFEHCI ANLFVIPFAI AIRHFAPPPF WQLAHSSADN FPALTVSHFI
260 270 280
TANLLPVMLG NIIGGAVLVS MCYRAIYLRQ EP
Length:282
Mass (Da):30,565
Last modified:February 1, 1997 - v1
Checksum:i403929CDF55EDE0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63654 Genomic DNA Translation: AAB88574.1
U00096 Genomic DNA Translation: AAC75545.1
AP009048 Genomic DNA Translation: BAA16381.1
PIRiC65025
RefSeqiNP_416987.1, NC_000913.3
WP_001244734.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75545; AAC75545; b2492
BAA16381; BAA16381; BAA16381
GeneIDi949032
KEGGiecj:JW2477
eco:b2492
PATRICifig|1411691.4.peg.4247

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63654 Genomic DNA Translation: AAB88574.1
U00096 Genomic DNA Translation: AAC75545.1
AP009048 Genomic DNA Translation: BAA16381.1
PIRiC65025
RefSeqiNP_416987.1, NC_000913.3
WP_001244734.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP77733
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261432, 7 interactors
DIPiDIP-9671N
IntActiP77733, 1 interactor
STRINGi316385.ECDH10B_2658

Protein family/group databases

TCDBi1.A.16.1.2 the formate-nitrite transporter (fnt) family

Proteomic databases

PaxDbiP77733
PRIDEiP77733

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75545; AAC75545; b2492
BAA16381; BAA16381; BAA16381
GeneIDi949032
KEGGiecj:JW2477
eco:b2492
PATRICifig|1411691.4.peg.4247

Organism-specific databases

EchoBASEiEB3972
EcoGeneiEG14220 focB

Phylogenomic databases

eggNOGiENOG4105TMB Bacteria
COG2116 LUCA
HOGENOMiHOG000271393
InParanoidiP77733
KOiK03459
PhylomeDBiP77733

Enzyme and pathway databases

BioCyciEcoCyc:FOCB-MONOMER

Miscellaneous databases

PROiPR:P77733

Family and domain databases

Gene3Di1.20.1080.10, 1 hit
InterProiView protein in InterPro
IPR023271 Aquaporin-like
IPR000292 For/NO2_transpt
IPR024002 For/NO2_transpt_CS
PANTHERiPTHR30520 PTHR30520, 1 hit
PfamiView protein in Pfam
PF01226 Form_Nir_trans, 1 hit
TIGRFAMsiTIGR00790 fnt, 1 hit
PROSITEiView protein in PROSITE
PS01005 FORMATE_NITRITE_TP_1, 1 hit
PS01006 FORMATE_NITRITE_TP_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiFOCB_ECOLI
AccessioniPrimary (citable) accession number: P77733
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 7, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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