UniProtKB - P77730 (YDCR_ECOLI)
Protein
Uncharacterized HTH-type transcriptional regulator YdcR
Gene
ydcR
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: InterPro
- pyridoxal phosphate binding Source: InterPro
- transaminase activity Source: GO_Central
GO - Biological processi
- alpha-amino acid metabolic process Source: GO_Central
- biosynthetic process Source: InterPro
Keywordsi
Molecular function | Aminotransferase, DNA-binding, Transferase |
Biological process | Transcription, Transcription regulation |
Ligand | Pyridoxal phosphate |
Enzyme and pathway databases
BioCyci | EcoCyc:G6750-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized HTH-type transcriptional regulator YdcR |
Gene namesi | Name:ydcR Ordered Locus Names:b1439, JW1434 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050708 | 1 – 468 | Uncharacterized HTH-type transcriptional regulator YdcRAdd BLAST | 468 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 312 | N6-(pyridoxal phosphate)lysineBy similarity | 1 |
Proteomic databases
jPOSTi | P77730 |
PaxDbi | P77730 |
PRIDEi | P77730 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260188, 15 interactors |
DIPi | DIP-28077N |
IntActi | P77730, 3 interactors |
STRINGi | 511145.b1439 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 69 | HTH gntR-typePROSITE-ProRule annotationAdd BLAST | 69 |
Sequence similaritiesi
In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.Curated
Phylogenomic databases
eggNOGi | COG1167, Bacteria |
HOGENOMi | CLU_017584_0_0_6 |
InParanoidi | P77730 |
PhylomeDBi | P77730 |
Family and domain databases
CDDi | cd07377, WHTH_GntR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 3.40.640.10, 1 hit 3.90.1150.10, 1 hit |
InterProi | View protein in InterPro IPR004839, Aminotransferase_I/II IPR015424, PyrdxlP-dep_Trfase IPR015422, PyrdxlP-dep_Trfase_dom1 IPR015421, PyrdxlP-dep_Trfase_major IPR000524, Tscrpt_reg_HTH_GntR IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00155, Aminotran_1_2, 1 hit PF00392, GntR, 1 hit |
SMARTi | View protein in SMART SM00345, HTH_GNTR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF53383, SSF53383, 1 hit |
PROSITEi | View protein in PROSITE PS50949, HTH_GNTR, 1 hit |
i Sequence
Sequence statusi: Complete.
P77730-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKYQQLAEQ LREQIASGIW QPGDRLPSLR DQVALSGMSF MTVSHAYQLL
60 70 80 90 100
ESQGYIIARP QSGYYVAPQA IKMPKAPVIP VTRDEAVDIN TYIFDMLQAS
110 120 130 140 150
RDPSVVPFAS AFPDPRLFPL QQLNRSLAQV SKTATAMSVI ENLPPGNAEL
160 170 180 190 200
RQAIARRYAL QGITISPDEI VITAGALEAL NLSLQAVTEP GDWVIVENPC
210 220 230 240 250
FYGALQALER LRLKALSVAT DVKEGIDLQA LELALQEYPV KACWLMTNSQ
260 270 280 290 300
NPLGFTLTPQ KKAQLVALLN QYNVTLIEDD VYSELYFGRE KPLPAKAWDR
310 320 330 340 350
HDGVLHCSSF SKCLVPGFRI GWVAAGKHAR KIQRLQLMST LSTSSPMQLA
360 370 380 390 400
LVDYLSTRRY DAHLRRLRRQ LAERKQRAWQ ALLRYLPAEV KIHHNDSGYF
410 420 430 440 450
LWLELPEPLD AGELSLAALT HHISIAPGKM FSTGENWSRF FRFNTAWQWG
460
EREEQAVKQL GKLIQERL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74521.1 AP009048 Genomic DNA Translation: BAA15069.1 |
PIRi | B64896 |
RefSeqi | NP_415956.1, NC_000913.3 WP_000760626.1, NZ_SSZK01000021.1 |
Genome annotation databases
EnsemblBacteriai | AAC74521; AAC74521; b1439 BAA15069; BAA15069; BAA15069 |
GeneIDi | 946004 |
KEGGi | ecj:JW1434 eco:b1439 |
PATRICi | fig|1411691.4.peg.829 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74521.1 AP009048 Genomic DNA Translation: BAA15069.1 |
PIRi | B64896 |
RefSeqi | NP_415956.1, NC_000913.3 WP_000760626.1, NZ_SSZK01000021.1 |
3D structure databases
SMRi | P77730 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260188, 15 interactors |
DIPi | DIP-28077N |
IntActi | P77730, 3 interactors |
STRINGi | 511145.b1439 |
Proteomic databases
jPOSTi | P77730 |
PaxDbi | P77730 |
PRIDEi | P77730 |
Genome annotation databases
EnsemblBacteriai | AAC74521; AAC74521; b1439 BAA15069; BAA15069; BAA15069 |
GeneIDi | 946004 |
KEGGi | ecj:JW1434 eco:b1439 |
PATRICi | fig|1411691.4.peg.829 |
Organism-specific databases
EchoBASEi | EB3524 |
Phylogenomic databases
eggNOGi | COG1167, Bacteria |
HOGENOMi | CLU_017584_0_0_6 |
InParanoidi | P77730 |
PhylomeDBi | P77730 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6750-MONOMER |
Miscellaneous databases
PROi | PR:P77730 |
Family and domain databases
CDDi | cd07377, WHTH_GntR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 3.40.640.10, 1 hit 3.90.1150.10, 1 hit |
InterProi | View protein in InterPro IPR004839, Aminotransferase_I/II IPR015424, PyrdxlP-dep_Trfase IPR015422, PyrdxlP-dep_Trfase_dom1 IPR015421, PyrdxlP-dep_Trfase_major IPR000524, Tscrpt_reg_HTH_GntR IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00155, Aminotran_1_2, 1 hit PF00392, GntR, 1 hit |
SMARTi | View protein in SMART SM00345, HTH_GNTR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF53383, SSF53383, 1 hit |
PROSITEi | View protein in PROSITE PS50949, HTH_GNTR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YDCR_ECOLI | |
Accessioni | P77730Primary (citable) accession number: P77730 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 27, 2002 |
Last sequence update: | February 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 154 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families