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Protein

Hydrogenase-4 component I

Gene

hyfI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Possible component of hydrogenase 4.1 Publication

Cofactori

[4Fe-4S] clusterCuratedNote: Binds 1 [4Fe-4S] cluster.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi41Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi47Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi111Iron-sulfur (4Fe-4S)Sequence analysis1
Metal bindingi141Iron-sulfur (4Fe-4S)Sequence analysis1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-151

Protein family/group databases

TCDBi3.D.1.9.1 the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-4 component I (EC:1.-.-.-)
Gene namesi
Name:hyfI1 Publication
Ordered Locus Names:b2489, JW5805
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14217 hyfI

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001187811 – 252Hydrogenase-4 component IAdd BLAST252

Proteomic databases

PaxDbiP77668
PRIDEiP77668

Interactioni

Protein-protein interaction databases

BioGridi4262153, 7 interactors
STRINGi316385.ECDH10B_2655

Structurei

3D structure databases

ProteinModelPortaliP77668
SMRiP77668
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 20 kDa subunit family.Curated

Phylogenomic databases

eggNOGiENOG4105C47 Bacteria
COG3260 LUCA
HOGENOMiHOG000228250
InParanoidiP77668
KOiK12144
OMAiLRIYHAM
PhylomeDBiP77668

Family and domain databases

InterProiView protein in InterPro
IPR006137 NADH_UbQ_OxRdtase-like_20kDa
IPR006138 NADH_UQ_OxRdtase_20Kd_su
PfamiView protein in Pfam
PF01058 Oxidored_q6, 1 hit
PROSITEiView protein in PROSITE
PS01150 COMPLEX1_20K, 1 hit

Sequencei

Sequence statusi: Complete.

P77668-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPVLTQHVS QPITLDEQTQ KMKRHLLQDI RRSAYVYRVD CGGCNACEIE
60 70 80 90 100
IFAAITPVFD AERFGIKVVS SPRHADILLF TGAVTRAMRM PALRAYESAP
110 120 130 140 150
DHKICVSYGA CGVGGGIFHD LYSVWGGSDT IVPIDVWIPG CPPTPAATIH
160 170 180 190 200
GFAVALGLLQ QKIHAVDYRD PTGVTMQPLW PQIPPSQRIA IEREARRLAG
210 220 230 240 250
YRQGREICDR LLRHLSDDPT GNRVNTWLRD ADDPRLNSIV QQLFRVLRGL

HD
Length:252
Mass (Da):28,101
Last modified:February 1, 1997 - v1
Checksum:i3BA49D62ABAEAEEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63654 Genomic DNA Translation: AAB88571.1
U00096 Genomic DNA Translation: AAC75542.1
AP009048 Genomic DNA Translation: BAA16377.2
PIRiH65024
RefSeqiNP_416984.1, NC_000913.3
WP_000075558.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75542; AAC75542; b2489
BAA16377; BAA16377; BAA16377
GeneIDi946966
KEGGiecj:JW5805
eco:b2489
PATRICifig|1411691.4.peg.4250

Similar proteinsi

Entry informationi

Entry nameiHYFI_ECOLI
AccessioniPrimary (citable) accession number: P77668
Secondary accession number(s): P76975
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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