UniProtKB - P77626 (SUTR_ECOLI)
Protein
HTH-type transcriptional regulator SutR
Gene
sutR
Organism
Escherichia coli (strain K12)
Status
Functioni
Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB, fliZ, cysE, ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes.1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 23 – 42 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: EcoCyc
- DNA-binding transcription factor activity Source: EcoCyc
- sequence-specific DNA binding Source: EcoCyc
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: EcoCyc
- positive regulation of transcription, DNA-templated Source: EcoCyc
- regulation of transcription, DNA-templated Source: GO_Central
Keywordsi
Molecular function | Activator, DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | EcoCyc:G6745-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: HTH-type transcriptional regulator SutRCuratedAlternative name(s): Sulfur utilization regulator1 Publication |
Gene namesi | Name:sutR1 Publication Synonyms:ydcN Ordered Locus Names:b1434, JW1430 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000149756 | 1 – 178 | HTH-type transcriptional regulator SutRAdd BLAST | 178 |
Proteomic databases
PaxDbi | P77626 |
PRIDEi | P77626 |
Expressioni
Inductioni
Negatively autoregulated.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260184, 6 interactors |
DIPi | DIP-11649N |
STRINGi | 511145.b1434 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 12 – 66 | HTH cro/C1-typePROSITE-ProRule annotationAdd BLAST | 55 |
Phylogenomic databases
eggNOGi | COG1396, Bacteria |
HOGENOMi | CLU_085376_5_0_6 |
InParanoidi | P77626 |
PhylomeDBi | P77626 |
Family and domain databases
CDDi | cd00093, HTH_XRE, 1 hit |
Gene3Di | 1.10.260.40, 1 hit 2.60.120.10, 1 hit |
InterProi | View protein in InterPro IPR001387, Cro/C1-type_HTH IPR013096, Cupin_2 IPR010982, Lambda_DNA-bd_dom_sf IPR014710, RmlC-like_jellyroll IPR011051, RmlC_Cupin_sf |
Pfami | View protein in Pfam PF07883, Cupin_2, 1 hit PF01381, HTH_3, 1 hit |
SMARTi | View protein in SMART SM00530, HTH_XRE, 1 hit |
SUPFAMi | SSF47413, SSF47413, 1 hit SSF51182, SSF51182, 1 hit |
PROSITEi | View protein in PROSITE PS50943, HTH_CROC1, 1 hit |
i Sequence
Sequence statusi: Complete.
P77626-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENLARFLST TLKQLRQQRG WSLSRLAEAT GVSKAMLGQI ERNESSPTVA
60 70 80 90 100
TLWKIATGLN VPFSTFISPP QSATPSVYDP QQQAMVITSL FPYDPQLCFE
110 120 130 140 150
HFSIQMASGA ISESTPHEKG VIEHVVVIDG QLDLCVDGEW QTLNCGEGVR
160 170
FAADVTHIYR NGGEQTVHFH SLIHYPRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74516.1 AP009048 Genomic DNA Translation: BAA15062.1 |
PIRi | E64895 |
RefSeqi | NP_415951.1, NC_000913.3 WP_000429155.1, NZ_SSZK01000021.1 |
Genome annotation databases
EnsemblBacteriai | AAC74516; AAC74516; b1434 BAA15062; BAA15062; BAA15062 |
GeneIDi | 946000 |
KEGGi | ecj:JW1430 eco:b1434 |
PATRICi | fig|1411691.4.peg.835 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74516.1 AP009048 Genomic DNA Translation: BAA15062.1 |
PIRi | E64895 |
RefSeqi | NP_415951.1, NC_000913.3 WP_000429155.1, NZ_SSZK01000021.1 |
3D structure databases
SMRi | P77626 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260184, 6 interactors |
DIPi | DIP-11649N |
STRINGi | 511145.b1434 |
Proteomic databases
PaxDbi | P77626 |
PRIDEi | P77626 |
Genome annotation databases
EnsemblBacteriai | AAC74516; AAC74516; b1434 BAA15062; BAA15062; BAA15062 |
GeneIDi | 946000 |
KEGGi | ecj:JW1430 eco:b1434 |
PATRICi | fig|1411691.4.peg.835 |
Phylogenomic databases
eggNOGi | COG1396, Bacteria |
HOGENOMi | CLU_085376_5_0_6 |
InParanoidi | P77626 |
PhylomeDBi | P77626 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6745-MONOMER |
Miscellaneous databases
PROi | PR:P77626 |
Family and domain databases
CDDi | cd00093, HTH_XRE, 1 hit |
Gene3Di | 1.10.260.40, 1 hit 2.60.120.10, 1 hit |
InterProi | View protein in InterPro IPR001387, Cro/C1-type_HTH IPR013096, Cupin_2 IPR010982, Lambda_DNA-bd_dom_sf IPR014710, RmlC-like_jellyroll IPR011051, RmlC_Cupin_sf |
Pfami | View protein in Pfam PF07883, Cupin_2, 1 hit PF01381, HTH_3, 1 hit |
SMARTi | View protein in SMART SM00530, HTH_XRE, 1 hit |
SUPFAMi | SSF47413, SSF47413, 1 hit SSF51182, SSF51182, 1 hit |
PROSITEi | View protein in PROSITE PS50943, HTH_CROC1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SUTR_ECOLI | |
Accessioni | P77626Primary (citable) accession number: P77626 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | February 1, 1997 | |
Last modified: | December 2, 2020 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |