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UniProtKB - P77611 (RSXC_ECOLI)

Entry version 174 (02 Jun 2021)
Sequence version 1 (01 Feb 1997)
Previous versions | rss
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Protein

Ion-translocating oxidoreductase complex subunit C

Gene

rsxC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity).

Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).

UniRule annotation1 Publication

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 2 [4Fe-4S] clusters per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi377Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi380Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi383Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi387Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi416Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi419Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi422Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi426Iron-sulfur 1 (4Fe-4S)UniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Biological processElectron transport, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:G6873-MONOMER

Protein family/group databases

Transport Classification Database

More...TCDBi		3.D.6.1.4, the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ion-translocating oxidoreductase complex subunit CUniRule annotationCurated (EC:7.-.-.-UniRule annotationCurated)
Alternative name(s):
Rsx electron transport complex subunit CUniRule annotationCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rsxC1 PublicationUniRule annotation
Synonyms:rnfC, ydgN
Ordered Locus Names:b1629, JW1621
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000732051 – 740Ion-translocating oxidoreductase complex subunit CAdd BLAST740

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P77611

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P77611

PRoteomics IDEntifications database

More...PRIDEi		P77611

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.

UniRule annotation1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4261728, 153 interactors

Database of interacting proteins

More...DIPi		DIP-28084N

Protein interaction database and analysis system

More...IntActi		P77611, 4 interactors

STRING: functional protein association networks

More...STRINGi		511145.b1629

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini369 – 3974Fe-4S ferredoxin-type 1UniRule annotationAdd BLAST29
Domaini407 – 4364Fe-4S ferredoxin-type 2UniRule annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni571 – 590DisorderedSequence analysisAdd BLAST20
Regioni602 – 716DisorderedSequence analysisAdd BLAST115

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi602 – 631Basic and acidic residuesSequence analysisAdd BLAST30
Compositional biasi656 – 695Basic and acidic residuesSequence analysisAdd BLAST40

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG4656, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_010808_2_1_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P77611

Database for complete collections of gene phylogenies

More...PhylomeDBi		P77611

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1060.10, 1 hit
3.40.50.11540, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00461, RsxC_RnfC, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR017896, 4Fe4S_Fe-S-bd
IPR017900, 4Fe4S_Fe_S_CS
IPR009051, Helical_ferredxn
IPR010208, Ion_transpt_RnfC/RsxC
IPR011538, Nuo51_FMN-bd
IPR037225, Nuo51_FMN-bd_sf
IPR026902, RnfC_N
IPR019554, Soluble_ligand-bd

The PANTHER Classification System

More...PANTHERi		PTHR43034, PTHR43034, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01512, Complex1_51K, 1 hit
PF12838, Fer4_7, 1 hit
PF13375, RnfC_N, 1 hit
PF10531, SLBB, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF142019, SSF142019, 1 hit
SSF46548, SSF46548, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01945, rnfC, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00198, 4FE4S_FER_1, 2 hits
PS51379, 4FE4S_FER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P77611-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKLFSAFRK NKIWDFNGGI HPPEMKTQSN GTPLRQVPLA QRFVIPLKQH 
        60         70         80         90        100
IGAEGELCVS VGDKVLRGQP LTRGRGKMLP VHAPTSGTVT AIAPHSTAHP 
       110        120        130        140        150
SALAELSVII DADGEDCWIP RDGWADYRTR SREELIERIH QFGVAGLGGA 
       160        170        180        190        200
GFPTGVKLQG GGDKIETLII NAAECEPYIT ADDRLMQDCA AQVVEGIRIL 
       210        220        230        240        250
AHILQPREIL IGIEDNKPQA ISMLRAVLAD SNDISLRVIP TKYPSGGAKQ 
       260        270        280        290        300
LTYILTGKQV PHGGRSSDIG VLMQNVGTAY AVKRAVIDGE PITERVVTLT 
       310        320        330        340        350
GEAIARPGNV WARLGTPVRH LLNDAGFCPS ADQMVIMGGP LMGFTLPWLD 
       360        370        380        390        400
VPVVKITNCL LAPSANELGE PQEEQSCIRC SACADACPAD LLPQQLYWFS 
       410        420        430        440        450
KGQQHDKATT HNIADCIECG ACAWVCPSNI PLVQYFRQEK AEIAAIRQEE 
       460        470        480        490        500
KRAAEAKARF EARQARLERE KAARLERHKS AAVQPAAKDK DAIAAALARV 
       510        520        530        540        550
KEKQAQATQP IVIKAGERPD NSAIIAAREA RKAQARAKQA ELQQTNDAAT 
       560        570        580        590        600
VADPRKTAVE AAIARAKARK LEQQQANAEP EQQVDPRKAA VEAAIARAKA 
       610        620        630        640        650
RKLEQQQANA EPEEQVDPRK AAVEAAIARA KARKLEQQQA NAEPEQQVDP 
       660        670        680        690        700
RKAAVEAAIA RAKARKREQQ PANAEPEEQV DPRKAAVEAA IARAKARKLE 
       710        720        730        740
QQQANAVPEE QVDPRKAAVA AAIARAQAKK AAQQKVVNED
Length:740
Mass (Da):80,172
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i381506475CD6E01F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74701.1
AP009048 Genomic DNA Translation: BAA15384.1

Protein sequence database of the Protein Information Resource

More...PIRi		G64919

NCBI Reference Sequences

More...RefSeqi		NP_416146.1, NC_000913.3
WP_000915778.1, NZ_SSUW01000005.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC74701; AAC74701; b1629
BAA15384; BAA15384; BAA15384

Database of genes from NCBI RefSeq genomes

More...GeneIDi		946137

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW1621
eco:b1629

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.632

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74701.1
AP009048 Genomic DNA Translation: BAA15384.1
PIRiG64919
RefSeqiNP_416146.1, NC_000913.3
WP_000915778.1, NZ_SSUW01000005.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi4261728, 153 interactors
DIPiDIP-28084N
IntActiP77611, 4 interactors
STRINGi511145.b1629

Protein family/group databases

TCDBi3.D.6.1.4, the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family

Proteomic databases

jPOSTiP77611
PaxDbiP77611
PRIDEiP77611

Genome annotation databases

EnsemblBacteriaiAAC74701; AAC74701; b1629
BAA15384; BAA15384; BAA15384
GeneIDi946137
KEGGiecj:JW1621
eco:b1629
PATRICifig|1411691.4.peg.632

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB3694

Phylogenomic databases

eggNOGiCOG4656, Bacteria
HOGENOMiCLU_010808_2_1_6
InParanoidiP77611
PhylomeDBiP77611

Enzyme and pathway databases

BioCyciEcoCyc:G6873-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P77611

Family and domain databases

Gene3Di1.10.1060.10, 1 hit
3.40.50.11540, 1 hit
HAMAPiMF_00461, RsxC_RnfC, 1 hit
InterProiView protein in InterPro
IPR017896, 4Fe4S_Fe-S-bd
IPR017900, 4Fe4S_Fe_S_CS
IPR009051, Helical_ferredxn
IPR010208, Ion_transpt_RnfC/RsxC
IPR011538, Nuo51_FMN-bd
IPR037225, Nuo51_FMN-bd_sf
IPR026902, RnfC_N
IPR019554, Soluble_ligand-bd
PANTHERiPTHR43034, PTHR43034, 1 hit
PfamiView protein in Pfam
PF01512, Complex1_51K, 1 hit
PF12838, Fer4_7, 1 hit
PF13375, RnfC_N, 1 hit
PF10531, SLBB, 1 hit
SUPFAMiSSF142019, SSF142019, 1 hit
SSF46548, SSF46548, 1 hit
TIGRFAMsiTIGR01945, rnfC, 1 hit
PROSITEiView protein in PROSITE
PS00198, 4FE4S_FER_1, 2 hits
PS51379, 4FE4S_FER_2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRSXC_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P77611
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2001
Last sequence update: February 1, 1997
Last modified: June 2, 2021
This is version 174 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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