UniProtKB - P77611 (RSXC_ECOLI)
Protein
Ion-translocating oxidoreductase complex subunit C
Gene
rsxC
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).UniRule annotation1 Publication
Cofactori
[4Fe-4S] clusterUniRule annotationNote: Binds 2 [4Fe-4S] clusters per subunit.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 377 | Iron-sulfur 1 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 380 | Iron-sulfur 1 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 383 | Iron-sulfur 1 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 387 | Iron-sulfur 2 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 416 | Iron-sulfur 2 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 419 | Iron-sulfur 2 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 422 | Iron-sulfur 2 (4Fe-4S)UniRule annotation | 1 | |
Metal bindingi | 426 | Iron-sulfur 1 (4Fe-4S)UniRule annotation | 1 |
GO - Molecular functioni
- 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- electron transfer activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
Keywordsi
Molecular function | Translocase |
Biological process | Electron transport, Transport |
Ligand | 4Fe-4S, Iron, Iron-sulfur, Metal-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:G6873-MONOMER |
Protein family/group databases
TCDBi | 3.D.6.1.4, the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family |
Names & Taxonomyi
Protein namesi | Recommended name: Ion-translocating oxidoreductase complex subunit CUniRule annotationCurated (EC:7.-.-.-UniRule annotationCurated)Alternative name(s): Rsx electron transport complex subunit CUniRule annotationCurated |
Gene namesi | Name:rsxC1 PublicationUniRule annotation Synonyms:rnfC, ydgN Ordered Locus Names:b1629, JW1621 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation
GO - Cellular componenti
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000073205 | 1 – 740 | Ion-translocating oxidoreductase complex subunit CAdd BLAST | 740 |
Proteomic databases
jPOSTi | P77611 |
PaxDbi | P77611 |
PRIDEi | P77611 |
Interactioni
Subunit structurei
The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.
UniRule annotation1 PublicationProtein-protein interaction databases
BioGRIDi | 4261728, 153 interactors |
DIPi | DIP-28084N |
IntActi | P77611, 4 interactors |
STRINGi | 511145.b1629 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 369 – 397 | 4Fe-4S ferredoxin-type 1UniRule annotationAdd BLAST | 29 | |
Domaini | 407 – 436 | 4Fe-4S ferredoxin-type 2UniRule annotationAdd BLAST | 30 |
Sequence similaritiesi
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG4656, Bacteria |
HOGENOMi | CLU_010808_2_1_6 |
InParanoidi | P77611 |
PhylomeDBi | P77611 |
Family and domain databases
Gene3Di | 1.10.1060.10, 1 hit 3.40.50.11540, 1 hit |
HAMAPi | MF_00461, RsxC_RnfC, 1 hit |
InterProi | View protein in InterPro IPR017896, 4Fe4S_Fe-S-bd IPR017900, 4Fe4S_Fe_S_CS IPR009051, Helical_ferredxn IPR010208, Ion_transpt_RnfC/RsxC IPR011538, Nuo51_FMN-bd IPR037225, Nuo51_FMN-bd_sf IPR026902, RnfC_N IPR019554, Soluble_ligand-bd |
PANTHERi | PTHR43034, PTHR43034, 1 hit |
Pfami | View protein in Pfam PF01512, Complex1_51K, 1 hit PF12838, Fer4_7, 1 hit PF13375, RnfC_N, 1 hit PF10531, SLBB, 1 hit |
SUPFAMi | SSF142019, SSF142019, 1 hit SSF46548, SSF46548, 1 hit |
TIGRFAMsi | TIGR01945, rnfC, 1 hit |
PROSITEi | View protein in PROSITE PS00198, 4FE4S_FER_1, 2 hits PS51379, 4FE4S_FER_2, 2 hits |
i Sequence
Sequence statusi: Complete.
P77611-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKLFSAFRK NKIWDFNGGI HPPEMKTQSN GTPLRQVPLA QRFVIPLKQH
60 70 80 90 100
IGAEGELCVS VGDKVLRGQP LTRGRGKMLP VHAPTSGTVT AIAPHSTAHP
110 120 130 140 150
SALAELSVII DADGEDCWIP RDGWADYRTR SREELIERIH QFGVAGLGGA
160 170 180 190 200
GFPTGVKLQG GGDKIETLII NAAECEPYIT ADDRLMQDCA AQVVEGIRIL
210 220 230 240 250
AHILQPREIL IGIEDNKPQA ISMLRAVLAD SNDISLRVIP TKYPSGGAKQ
260 270 280 290 300
LTYILTGKQV PHGGRSSDIG VLMQNVGTAY AVKRAVIDGE PITERVVTLT
310 320 330 340 350
GEAIARPGNV WARLGTPVRH LLNDAGFCPS ADQMVIMGGP LMGFTLPWLD
360 370 380 390 400
VPVVKITNCL LAPSANELGE PQEEQSCIRC SACADACPAD LLPQQLYWFS
410 420 430 440 450
KGQQHDKATT HNIADCIECG ACAWVCPSNI PLVQYFRQEK AEIAAIRQEE
460 470 480 490 500
KRAAEAKARF EARQARLERE KAARLERHKS AAVQPAAKDK DAIAAALARV
510 520 530 540 550
KEKQAQATQP IVIKAGERPD NSAIIAAREA RKAQARAKQA ELQQTNDAAT
560 570 580 590 600
VADPRKTAVE AAIARAKARK LEQQQANAEP EQQVDPRKAA VEAAIARAKA
610 620 630 640 650
RKLEQQQANA EPEEQVDPRK AAVEAAIARA KARKLEQQQA NAEPEQQVDP
660 670 680 690 700
RKAAVEAAIA RAKARKREQQ PANAEPEEQV DPRKAAVEAA IARAKARKLE
710 720 730 740
QQQANAVPEE QVDPRKAAVA AAIARAQAKK AAQQKVVNED
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74701.1 AP009048 Genomic DNA Translation: BAA15384.1 |
PIRi | G64919 |
RefSeqi | NP_416146.1, NC_000913.3 WP_000915778.1, NZ_SSUW01000005.1 |
Genome annotation databases
EnsemblBacteriai | AAC74701; AAC74701; b1629 BAA15384; BAA15384; BAA15384 |
GeneIDi | 946137 |
KEGGi | ecj:JW1621 eco:b1629 |
PATRICi | fig|1411691.4.peg.632 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74701.1 AP009048 Genomic DNA Translation: BAA15384.1 |
PIRi | G64919 |
RefSeqi | NP_416146.1, NC_000913.3 WP_000915778.1, NZ_SSUW01000005.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261728, 153 interactors |
DIPi | DIP-28084N |
IntActi | P77611, 4 interactors |
STRINGi | 511145.b1629 |
Protein family/group databases
TCDBi | 3.D.6.1.4, the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family |
Proteomic databases
jPOSTi | P77611 |
PaxDbi | P77611 |
PRIDEi | P77611 |
Genome annotation databases
EnsemblBacteriai | AAC74701; AAC74701; b1629 BAA15384; BAA15384; BAA15384 |
GeneIDi | 946137 |
KEGGi | ecj:JW1621 eco:b1629 |
PATRICi | fig|1411691.4.peg.632 |
Organism-specific databases
EchoBASEi | EB3694 |
Phylogenomic databases
eggNOGi | COG4656, Bacteria |
HOGENOMi | CLU_010808_2_1_6 |
InParanoidi | P77611 |
PhylomeDBi | P77611 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6873-MONOMER |
Miscellaneous databases
PROi | PR:P77611 |
Family and domain databases
Gene3Di | 1.10.1060.10, 1 hit 3.40.50.11540, 1 hit |
HAMAPi | MF_00461, RsxC_RnfC, 1 hit |
InterProi | View protein in InterPro IPR017896, 4Fe4S_Fe-S-bd IPR017900, 4Fe4S_Fe_S_CS IPR009051, Helical_ferredxn IPR010208, Ion_transpt_RnfC/RsxC IPR011538, Nuo51_FMN-bd IPR037225, Nuo51_FMN-bd_sf IPR026902, RnfC_N IPR019554, Soluble_ligand-bd |
PANTHERi | PTHR43034, PTHR43034, 1 hit |
Pfami | View protein in Pfam PF01512, Complex1_51K, 1 hit PF12838, Fer4_7, 1 hit PF13375, RnfC_N, 1 hit PF10531, SLBB, 1 hit |
SUPFAMi | SSF142019, SSF142019, 1 hit SSF46548, SSF46548, 1 hit |
TIGRFAMsi | TIGR01945, rnfC, 1 hit |
PROSITEi | View protein in PROSITE PS00198, 4FE4S_FER_1, 2 hits PS51379, 4FE4S_FER_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RSXC_ECOLI | |
Accessioni | P77611Primary (citable) accession number: P77611 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 24, 2001 |
Last sequence update: | February 1, 1997 | |
Last modified: | December 2, 2020 | |
This is version 173 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families