We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P77561 (YDEP_ECOLI)
Protein
Protein YdeP
Gene
ydeP
Organism
Escherichia coli (strain K12)
Status
Functioni
Probably involved in acid resistance.
2 PublicationsCofactori
Protein has several cofactor binding sites:- [4Fe-4S] clusterCuratedNote: Binds 1 [4Fe-4S] cluster.Curated
- Mo-bis(molybdopterin guanine dinucleotide)By similarityNote: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 49 | Iron-sulfur (4Fe-4S)By similarity | 1 | |
Metal bindingi | 52 | Iron-sulfur (4Fe-4S)By similarity | 1 |
GO - Molecular functioni
- 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- formate dehydrogenase (NAD+) activity Source: InterPro
- molybdenum ion binding Source: InterPro
GO - Biological processi
- response to acidic pH Source: EcoCyc
Keywordsi
Molecular function | Oxidoreductase |
Ligand | 4Fe-4S, Iron, Iron-sulfur, Metal-binding, Molybdenum |
Enzyme and pathway databases
BioCyci | EcoCyc:G6791-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Protein YdeP |
Gene namesi | Name:ydeP Ordered Locus Names:b1501, JW1495 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000063227 | 1 – 759 | Protein YdePAdd BLAST | 759 |
Proteomic databases
PaxDbi | P77561 |
PRIDEi | P77561 |
Expressioni
Inductioni
By EvgA.2 Publications
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260213, 9 interactors 850416, 1 interactor |
DIPi | DIP-28057N |
IntActi | P77561, 11 interactors |
STRINGi | 511145.b1501 |
Family & Domainsi
Sequence similaritiesi
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.Curated
Phylogenomic databases
eggNOGi | COG0243, Bacteria |
HOGENOMi | CLU_000422_16_1_6 |
InParanoidi | P77561 |
PhylomeDBi | P77561 |
Family and domain databases
CDDi | cd02787, MopB_CT_ydeP, 1 hit cd02767, MopB_ydeP, 1 hit |
InterProi | View protein in InterPro IPR009010, Asp_de-COase-like_dom_sf IPR037951, MopB_CT_YdeP IPR006657, MoPterin_dinucl-bd_dom IPR006656, Mopterin_OxRdtase IPR010046, Mopterin_OxRdtse_a_bac IPR041953, YdeP_MopB |
PANTHERi | PTHR43105:SF4, PTHR43105:SF4, 1 hit |
Pfami | View protein in Pfam PF00384, Molybdopterin, 1 hit PF01568, Molydop_binding, 1 hit |
SUPFAMi | SSF50692, SSF50692, 1 hit |
TIGRFAMsi | TIGR01701, Fdhalpha-like, 1 hit |
i Sequence
Sequence statusi: Complete.
P77561-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKKIESYQG AAGGWGAVKS VANAVRKQMD IRQDVIAMFD MNKPEGFDCP
60 70 80 90 100
GCAWPDPKHS ASFDICENGA KAIAWEVTDK QVNASFFAEN TVQSLLTWGD
110 120 130 140 150
HELEAAGRLT QPLKYDAVSD CYKPLSWQQA FDEIGARLQS YSDPNQVEFY
160 170 180 190 200
TSGRTSNEAA FLYQLFAREY GSNNFPDCSN MCHEPTSVGL AASIGVGKGT
210 220 230 240 250
VLLEDFEKCD LVICIGHNPG TNHPRMLTSL RALVKRGAKM IAINPLQERG
260 270 280 290 300
LERFTAPQNP FEMLTNSETQ LASAYYNVRI GGDMALLKGM MRLLIERDDA
310 320 330 340 350
ASAAGRPSLL DDEFIQTHTV GFDELRRDVL NSEWKDIERI SGLSQTQIAE
360 370 380 390 400
LADAYAAAER TIICYGMGIT QHEHGTQNVQ QLVNLLLMKG NIGKPGAGIC
410 420 430 440 450
PLRGHSNVQG DRTVGITEKP SAEFLARLGE RYGFTPPHAP GHAAIASMQA
460 470 480 490 500
ICTGQARALI CMGGNFALAM PDREASAVPL TQLDLAVHVA TKLNRSHLLT
510 520 530 540 550
ARHSYILPVL GRSEIDMQKN GAQAVTVEDS MSMIHASRGV LKPAGVMLKS
560 570 580 590 600
ECAVVAGIAQ AALPQSVVAW EYLVEDYDRI RNDIEAVLPE FADYNQRIRH
610 620 630 640 650
PGGFHLINAA AERRWMTPSG KANFITSKGL LEDPSSAFNS KLVMATVRSH
660 670 680 690 700
DQYNTTIYGM DDRYRGVFGQ RDVVFMSAKQ AKICRVKNGE RVNLIALTPD
710 720 730 740 750
GKRSSRRMDR LKVVIYPMAD RSLVTYFPES NHMLTLDNHD PLSGIPGYKS
IPVELEPSN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74574.1 AP009048 Genomic DNA Translation: BAA15174.1 |
PIRi | H64903 |
RefSeqi | NP_416018.1, NC_000913.3 WP_000726691.1, NZ_SSZK01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC74574; AAC74574; b1501 BAA15174; BAA15174; BAA15174 |
GeneIDi | 946055 |
KEGGi | ecj:JW1495 eco:b1501 |
PATRICi | fig|1411691.4.peg.765 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74574.1 AP009048 Genomic DNA Translation: BAA15174.1 |
PIRi | H64903 |
RefSeqi | NP_416018.1, NC_000913.3 WP_000726691.1, NZ_SSZK01000001.1 |
3D structure databases
SMRi | P77561 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260213, 9 interactors 850416, 1 interactor |
DIPi | DIP-28057N |
IntActi | P77561, 11 interactors |
STRINGi | 511145.b1501 |
Proteomic databases
PaxDbi | P77561 |
PRIDEi | P77561 |
Genome annotation databases
EnsemblBacteriai | AAC74574; AAC74574; b1501 BAA15174; BAA15174; BAA15174 |
GeneIDi | 946055 |
KEGGi | ecj:JW1495 eco:b1501 |
PATRICi | fig|1411691.4.peg.765 |
Organism-specific databases
EchoBASEi | EB3559 |
Phylogenomic databases
eggNOGi | COG0243, Bacteria |
HOGENOMi | CLU_000422_16_1_6 |
InParanoidi | P77561 |
PhylomeDBi | P77561 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6791-MONOMER |
Miscellaneous databases
PROi | PR:P77561 |
Family and domain databases
CDDi | cd02787, MopB_CT_ydeP, 1 hit cd02767, MopB_ydeP, 1 hit |
InterProi | View protein in InterPro IPR009010, Asp_de-COase-like_dom_sf IPR037951, MopB_CT_YdeP IPR006657, MoPterin_dinucl-bd_dom IPR006656, Mopterin_OxRdtase IPR010046, Mopterin_OxRdtse_a_bac IPR041953, YdeP_MopB |
PANTHERi | PTHR43105:SF4, PTHR43105:SF4, 1 hit |
Pfami | View protein in Pfam PF00384, Molybdopterin, 1 hit PF01568, Molydop_binding, 1 hit |
SUPFAMi | SSF50692, SSF50692, 1 hit |
TIGRFAMsi | TIGR01701, Fdhalpha-like, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YDEP_ECOLI | |
Accessioni | P77561Primary (citable) accession number: P77561 Secondary accession number(s): P78160 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 27, 2002 |
Last sequence update: | February 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 149 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families