UniProtKB - P77509 (YPHE_ECOLI)
Protein
Uncharacterized ABC transporter ATP-binding protein YphE
Gene
yphE
Organism
Escherichia coli (strain K12)
Status
Functioni
Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 43 – 50 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-KW
Keywordsi
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:YPHE-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.2.27, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized ABC transporter ATP-binding protein YphE |
Gene namesi | Name:yphE Ordered Locus Names:b2547, JW2531 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093197 | 1 – 503 | Uncharacterized ABC transporter ATP-binding protein YphEAdd BLAST | 503 |
Proteomic databases
PaxDbi | P77509 |
PRIDEi | P77509 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261315, 141 interactors |
ComplexPortali | CPX-4468, YphDEF ABC transporter complex |
DIPi | DIP-12830N |
IntActi | P77509, 7 interactors |
STRINGi | 511145.b2547 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 249 | ABC transporter 1PROSITE-ProRule annotationAdd BLAST | 242 | |
Domaini | 261 – 499 | ABC transporter 2PROSITE-ProRule annotationAdd BLAST | 239 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG1129, Bacteria |
HOGENOMi | CLU_000604_92_3_6 |
InParanoidi | P77509 |
PhylomeDBi | P77509 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits |
i Sequence
Sequence statusi: Complete.
P77509-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFTATEAVPV AKVVAGNKRY PGVVALDNVN FTLNKGEVRA LLGKNGAGKS
60 70 80 90 100
TLIRMLTGSE RPDSGDIWIG ETRLEGDEAT LTRRAAELGV RAVYQELSLV
110 120 130 140 150
EGLTVAENLC LGQWPRRNGM IDYLQMAQDA QRCLQALGVD VSPEQLVSTL
160 170 180 190 200
SPAQKQLVEI ARVMKGEPRV VILDEPTSSL ASAEVELVIS AVKKMSALGV
210 220 230 240 250
AVIYVSHRME EIRRIASCAT VMRDGQVAGD VMLENTSTHH IVSLMLGRDH
260 270 280 290 300
VDIAPVAPQE IVDQAVLEVR ALRHKPKLED ISFTLRRGEV LGIAGLLGAG
310 320 330 340 350
RSELLKAIVG LEEYEQGEIV INGEKITRPD YGDMLKRGIG YTPENRKEAG
360 370 380 390 400
IIPWLGVDEN TVLTNRQKIS ANGVLQWSTI RRLTEEVMQR MTVKAASSET
410 420 430 440 450
PIGTLSGGNQ QKVVIGRWVY AASQILLLDE PTRGVDIEAK QQIYRIVREL
460 470 480 490 500
AAEGKSVVFI SSEVEELPLV CDRILLLQHG TFSQEFHAPV NVDELMSAIL
SVH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75600.1 AP009048 Genomic DNA Translation: BAA16449.1 |
PIRi | B65032 |
RefSeqi | NP_417042.1, NC_000913.3 WP_000493470.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC75600; AAC75600; b2547 BAA16449; BAA16449; BAA16449 |
GeneIDi | 57732351 948990 |
KEGGi | ecj:JW2531 eco:b2547 |
PATRICi | fig|1411691.4.peg.4187 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75600.1 AP009048 Genomic DNA Translation: BAA16449.1 |
PIRi | B65032 |
RefSeqi | NP_417042.1, NC_000913.3 WP_000493470.1, NZ_LN832404.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261315, 141 interactors |
ComplexPortali | CPX-4468, YphDEF ABC transporter complex |
DIPi | DIP-12830N |
IntActi | P77509, 7 interactors |
STRINGi | 511145.b2547 |
Protein family/group databases
TCDBi | 3.A.1.2.27, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P77509 |
PRIDEi | P77509 |
Genome annotation databases
EnsemblBacteriai | AAC75600; AAC75600; b2547 BAA16449; BAA16449; BAA16449 |
GeneIDi | 57732351 948990 |
KEGGi | ecj:JW2531 eco:b2547 |
PATRICi | fig|1411691.4.peg.4187 |
Organism-specific databases
EchoBASEi | EB3239 |
Phylogenomic databases
eggNOGi | COG1129, Bacteria |
HOGENOMi | CLU_000604_92_3_6 |
InParanoidi | P77509 |
PhylomeDBi | P77509 |
Enzyme and pathway databases
BioCyci | EcoCyc:YPHE-MONOMER |
Miscellaneous databases
PROi | PR:P77509 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YPHE_ECOLI | |
Accessioni | P77509Primary (citable) accession number: P77509 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | February 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families