UniProtKB - P77409 (YDHU_ECOLI)
Protein
Putative cytochrome YdhU
Gene
ydhU
Organism
Escherichia coli (strain K12)
Status
Functioni
Cofactori
hemeBy similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 77 | Iron (heme B 1 axial ligand); via tele nitrogenBy similarity | 1 | |
Metal bindingi | 111 | Iron (heme B 2 axial ligand); via tele nitrogenBy similarity | 1 | |
Metal bindingi | 223 | Iron (heme B 2 axial ligand); via tele nitrogenBy similarity | 1 | |
Metal bindingi | 237 | Iron (heme B 1 axial ligand); via tele nitrogenBy similarity | 1 | |
Binding sitei | 237 | Menaquinone; via pros nitrogenBy similarity | 1 |
GO - Molecular functioni
- electron transfer activity Source: InterPro
- heme binding Source: GO_Central
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- oxidation-reduction process Source: GO_Central
- respiratory electron transport chain Source: InterPro
Keywordsi
Ligand | Iron, Metal-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:G6898-MONOMER ECOL316407:JW1660-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative cytochrome YdhUCuratedAlternative name(s): Protein PhsC homologCurated |
Gene namesi | Name:ydhU Ordered Locus Names:b1670, JW1660 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane Curated; Multi-pass membrane protein Sequence analysis
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 25 – 45 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 81 – 101 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 108 – 128 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 182 – 202 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 224 – 244 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- integral component of plasma membrane Source: GO_Central
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000058407 | 1 – 261 | Putative cytochrome YdhUAdd BLAST | 261 |
Proteomic databases
PaxDbi | P77409 |
PRIDEi | P77409 |
Expressioni
Inductioni
Up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions. Repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively.1 Publication
Interactioni
Protein-protein interaction databases
BioGridi | 4262230, 6 interactors 849981, 1 interactor |
DIPi | DIP-11740N |
IntActi | P77409, 4 interactors |
STRINGi | 511145.b1670 |
Family & Domainsi
Sequence similaritiesi
Belongs to the PhsC family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG4108NWD Bacteria COG4117 LUCA |
HOGENOMi | HOG000004863 |
InParanoidi | P77409 |
KOi | K08354 |
PhylomeDBi | P77409 |
Family and domain databases
InterProi | View protein in InterPro IPR011577 Cyt_b561_bac/Ni-Hgenase IPR016174 Di-haem_cyt_TM |
Pfami | View protein in Pfam PF01292 Ni_hydr_CYTB, 1 hit |
SUPFAMi | SSF81342 SSF81342, 1 hit |
i Sequence
Sequence statusi: Complete.
P77409-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNPSQHAEQF QSQLANYVPQ FTPEFWPVWL IIAGVLLVGM WLVLGLHALL
60 70 80 90 100
RARGVKKSAT DHGEKIYLYS KAVRLWHWSN ALLFVLLLAS GLINHFAMVG
110 120 130 140 150
ATAVKSLVAV HEVCGFLLLA CWLGFVLINA VGDNGHHYRI RRQGWLERAA
160 170 180 190 200
KQTRFYLFGI MQGEEHPFPA TTQSKFNPLQ QVAYVGVMYG LLPLLLLTGL
210 220 230 240 250
LCLYPQAVGD VFPGVRYWLL QTHFALAFIS LFFIFGHLYL CTTGRTPHET
260
FKSMVDGYHR H
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U68703 Genomic DNA Translation: AAB47946.1 U00096 Genomic DNA Translation: AAC74740.1 AP009048 Genomic DNA Translation: BAA15442.1 |
PIRi | F64924 |
RefSeqi | NP_416185.1, NC_000913.3 WP_001069979.1, NZ_SSZK01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC74740; AAC74740; b1670 BAA15442; BAA15442; BAA15442 |
GeneIDi | 945608 |
KEGGi | ecj:JW1660 eco:b1670 |
PATRICi | fig|1411691.4.peg.589 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U68703 Genomic DNA Translation: AAB47946.1 U00096 Genomic DNA Translation: AAC74740.1 AP009048 Genomic DNA Translation: BAA15442.1 |
PIRi | F64924 |
RefSeqi | NP_416185.1, NC_000913.3 WP_001069979.1, NZ_SSZK01000001.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGridi | 4262230, 6 interactors 849981, 1 interactor |
DIPi | DIP-11740N |
IntActi | P77409, 4 interactors |
STRINGi | 511145.b1670 |
Proteomic databases
PaxDbi | P77409 |
PRIDEi | P77409 |
Genome annotation databases
EnsemblBacteriai | AAC74740; AAC74740; b1670 BAA15442; BAA15442; BAA15442 |
GeneIDi | 945608 |
KEGGi | ecj:JW1660 eco:b1670 |
PATRICi | fig|1411691.4.peg.589 |
Organism-specific databases
EchoBASEi | EB3713 |
Phylogenomic databases
eggNOGi | ENOG4108NWD Bacteria COG4117 LUCA |
HOGENOMi | HOG000004863 |
InParanoidi | P77409 |
KOi | K08354 |
PhylomeDBi | P77409 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6898-MONOMER ECOL316407:JW1660-MONOMER |
Miscellaneous databases
PROi | PR:P77409 |
Family and domain databases
InterProi | View protein in InterPro IPR011577 Cyt_b561_bac/Ni-Hgenase IPR016174 Di-haem_cyt_TM |
Pfami | View protein in Pfam PF01292 Ni_hydr_CYTB, 1 hit |
SUPFAMi | SSF81342 SSF81342, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YDHU_ECOLI | |
Accessioni | P77409Primary (citable) accession number: P77409 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | February 1, 1997 | |
Last modified: | November 13, 2019 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene