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UniProtKB - P77389 (YDHP_ECOLI)
Protein
Inner membrane transport protein YdhP
Gene
ydhP
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:B1657-MONOMER |
Protein family/group databases
TCDBi | 2.A.1.2.65, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Inner membrane transport protein YdhP |
Gene namesi | Name:ydhP Ordered Locus Names:b1657, JW1649 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 6 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 7 – 27 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 28 – 43 | PeriplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 44 – 64 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 65 – 70 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 71 – 91 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 92 – 100 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 101 – 121 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 122 – 130 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 131 – 151 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 152 – 159 | PeriplasmicSequence analysis | 8 | |
Transmembranei | 160 – 180 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 181 – 203 | CytoplasmicSequence analysisAdd BLAST | 23 | |
Transmembranei | 204 – 224 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 225 – 236 | PeriplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 237 – 257 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 258 – 266 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 267 – 287 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 288 – 290 | PeriplasmicSequence analysis | 3 | |
Transmembranei | 291 – 311 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 312 – 330 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 331 – 351 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 352 – 356 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 357 – 377 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 378 – 389 | CytoplasmicSequence analysisAdd BLAST | 12 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000173402 | 1 – 389 | Inner membrane transport protein YdhPAdd BLAST | 389 |
Proteomic databases
PaxDbi | P77389 |
PRIDEi | P77389 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260270, 170 interactors |
STRINGi | 511145.b1657 |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2814, Bacteria |
HOGENOMi | CLU_001265_61_2_6 |
InParanoidi | P77389 |
OMAi | EFAPMGL |
PhylomeDBi | P77389 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
P77389-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKINYPLLAL AIGAFGIGTT EFSPMGLLPV IARGVDVSIP AAGMLISAYA
60 70 80 90 100
VGVMVGAPLM TLLLSHRARR SALIFLMAIF TLGNVLSAIA PDYMTLMLSR
110 120 130 140 150
ILTSLNHGAF FGLGSVVAAS VVPKHKQASA VATMFMGLTL ANIGGVPAAT
160 170 180 190 200
WLGETIGWRM SFLATAGLGV ISMVSLFFSL PKGGAGARPE VKKELAVLMR
210 220 230 240 250
PQVLSALLTT VLGAGAMFTL YTYISPVLQS ITHATPVFVT AMLVLIGVGF
260 270 280 290 300
SIGNYLGGKL ADRSVNGTLK GFLLLLMVIM LAIPFLARNE FGAAISMVVW
310 320 330 340 350
GAATFAVVPP LQMRVMRVAS EAPGLSSSVN IGAFNLGNAL GAAAGGAVIS
360 370 380
AGLGYSFVPV MGAIVAGLAL LLVFMSARKQ PETVCVANS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74729.1 AP009048 Genomic DNA Translation: BAA15423.1 |
PIRi | C64923 |
RefSeqi | NP_416174.1, NC_000913.3 WP_000701040.1, NZ_STEB01000003.1 |
Genome annotation databases
EnsemblBacteriai | AAC74729; AAC74729; b1657 BAA15423; BAA15423; BAA15423 |
GeneIDi | 66674451 947340 |
KEGGi | ecj:JW1649 eco:b1657 |
PATRICi | fig|1411691.4.peg.601 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74729.1 AP009048 Genomic DNA Translation: BAA15423.1 |
PIRi | C64923 |
RefSeqi | NP_416174.1, NC_000913.3 WP_000701040.1, NZ_STEB01000003.1 |
3D structure databases
AlphaFoldDBi | P77389 |
SMRi | P77389 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260270, 170 interactors |
STRINGi | 511145.b1657 |
Protein family/group databases
TCDBi | 2.A.1.2.65, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P77389 |
PRIDEi | P77389 |
Genome annotation databases
EnsemblBacteriai | AAC74729; AAC74729; b1657 BAA15423; BAA15423; BAA15423 |
GeneIDi | 66674451 947340 |
KEGGi | ecj:JW1649 eco:b1657 |
PATRICi | fig|1411691.4.peg.601 |
Organism-specific databases
EchoBASEi | EB3708 |
Phylogenomic databases
eggNOGi | COG2814, Bacteria |
HOGENOMi | CLU_001265_61_2_6 |
InParanoidi | P77389 |
OMAi | EFAPMGL |
PhylomeDBi | P77389 |
Enzyme and pathway databases
BioCyci | EcoCyc:B1657-MONOMER |
Miscellaneous databases
PROi | PR:P77389 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YDHP_ECOLI | |
Accessioni | P77389Primary (citable) accession number: P77389 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2002 |
Last sequence update: | February 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families