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UniProtKB - P77360 (YPHC_ECOLI)
Protein
Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC
Gene
yphC
Organism
Escherichia coli (strain K12)
Status
Functioni
Cofactori
Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 40 | Zinc 1; catalyticBy similarity | 1 | |
Metal bindingi | 70 | Zinc 1; catalyticBy similarity | 1 | |
Metal bindingi | 100 | Zinc 2By similarity | 1 | |
Metal bindingi | 103 | Zinc 2By similarity | 1 | |
Metal bindingi | 106 | Zinc 2By similarity | 1 | |
Metal bindingi | 114 | Zinc 2By similarity | 1 | |
Metal bindingi | 158 | Zinc 1; catalyticBy similarity | 1 |
GO - Molecular functioni
- oxidoreductase activity Source: UniProtKB-KW
- zinc ion binding Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | EcoCyc:YPHC-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:yphC Ordered Locus Names:b2545, JW5842 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000160899 | 1 – 353 | Uncharacterized zinc-type alcohol dehydrogenase-like protein YphCAdd BLAST | 353 |
Proteomic databases
PaxDbi | P77360 |
PRIDEi | P77360 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261318, 8 interactors |
STRINGi | 511145.b2545 |
Family & Domainsi
Sequence similaritiesi
Belongs to the zinc-containing alcohol dehydrogenase family.Curated
Phylogenomic databases
eggNOGi | COG1063, Bacteria |
HOGENOMi | CLU_026673_11_2_6 |
InParanoidi | P77360 |
PhylomeDBi | P77360 |
Family and domain databases
InterProi | View protein in InterPro IPR013149, ADH_C IPR013154, ADH_N IPR002328, ADH_Zn_CS IPR011032, GroES-like_sf IPR036291, NAD(P)-bd_dom_sf IPR020843, PKS_ER |
Pfami | View protein in Pfam PF08240, ADH_N, 1 hit PF00107, ADH_zinc_N, 1 hit |
SMARTi | View protein in SMART SM00829, PKS_ER, 1 hit |
SUPFAMi | SSF50129, SSF50129, 1 hit SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00059, ADH_ZINC, 1 hit |
i Sequence
Sequence statusi: Complete.
P77360-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKTMLAAYLP GNSTVDLREV AVPTPGINQV LIKMKSSGIC GSDVHYIYHQ
60 70 80 90 100
HRATAAAPDK PLYQGFINGH EPCGQIVAMG QGCRHFKEGD RVLVYHISGC
110 120 130 140 150
GFCPNCRRGF PISCTGEGKA AYGWQRDGGH AEYLLAEEKD LILLPDALSY
160 170 180 190 200
EDGAFISCGV GTAYEGILRG EVSGSDNVLV VGLGPVGMMA MMLAKGRGAK
210 220 230 240 250
RIIGVDMLPE RLAMAKQLGV MDHGYLATTE GLPQIIAELT HGGADVALDC
260 270 280 290 300
SGNAAGRLLA LQSTADWGRV VYIGETGKVE FEVSADLMHH QRRIIGSWVT
310 320 330 340 350
SLFHMEKCAH DLTDWKLWPR NAITHRFSLE QAGDAYALMA SGKCGKVVIN
FPD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75598.2 AP009048 Genomic DNA Translation: BAA16447.2 |
PIRi | H65031 |
RefSeqi | NP_417040.2, NC_000913.3 WP_001393448.1, NZ_CP047127.1 |
Genome annotation databases
EnsemblBacteriai | AAC75598; AAC75598; b2545 BAA16447; BAA16447; BAA16447 |
GeneIDi | 947019 |
KEGGi | ecj:JW5842 eco:b2545 |
PATRICi | fig|1411691.4.peg.4189 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75598.2 AP009048 Genomic DNA Translation: BAA16447.2 |
PIRi | H65031 |
RefSeqi | NP_417040.2, NC_000913.3 WP_001393448.1, NZ_CP047127.1 |
3D structure databases
SMRi | P77360 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261318, 8 interactors |
STRINGi | 511145.b2545 |
Proteomic databases
PaxDbi | P77360 |
PRIDEi | P77360 |
Genome annotation databases
EnsemblBacteriai | AAC75598; AAC75598; b2545 BAA16447; BAA16447; BAA16447 |
GeneIDi | 947019 |
KEGGi | ecj:JW5842 eco:b2545 |
PATRICi | fig|1411691.4.peg.4189 |
Organism-specific databases
EchoBASEi | EB3237 |
Phylogenomic databases
eggNOGi | COG1063, Bacteria |
HOGENOMi | CLU_026673_11_2_6 |
InParanoidi | P77360 |
PhylomeDBi | P77360 |
Enzyme and pathway databases
BioCyci | EcoCyc:YPHC-MONOMER |
Miscellaneous databases
PROi | PR:P77360 |
Family and domain databases
InterProi | View protein in InterPro IPR013149, ADH_C IPR013154, ADH_N IPR002328, ADH_Zn_CS IPR011032, GroES-like_sf IPR036291, NAD(P)-bd_dom_sf IPR020843, PKS_ER |
Pfami | View protein in Pfam PF08240, ADH_N, 1 hit PF00107, ADH_zinc_N, 1 hit |
SMARTi | View protein in SMART SM00829, PKS_ER, 1 hit |
SUPFAMi | SSF50129, SSF50129, 1 hit SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00059, ADH_ZINC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YPHC_ECOLI | |
Accessioni | P77360Primary (citable) accession number: P77360 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | May 30, 2000 | |
Last modified: | December 2, 2020 | |
This is version 140 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families