UniProtKB - P77328 (YBBY_ECOLI)
Protein
Putative purine permease YbbY
Gene
ybbY
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- xanthine transmembrane transporter activity Source: GO_Central
GO - Biological processi
- xanthine transport Source: GO_Central
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:G6282-MONOMER |
Protein family/group databases
TCDBi | 2.A.40.5.1, the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family |
Names & Taxonomyi
Protein namesi | Recommended name: Putative purine permease YbbY |
Gene namesi | Name:ybbY Synonyms:glxB4 Ordered Locus Names:b0513, JW0501 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- integral component of plasma membrane Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 17 | PeriplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 18 – 38 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 39 – 42 | CytoplasmicSequence analysis | 4 | |
Transmembranei | 43 – 63 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 64 – 68 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 69 – 89 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 90 – 102 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 103 – 123 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 124 – 130 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 131 – 151 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 152 – 169 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 170 – 190 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 191 – 196 | PeriplasmicSequence analysis | 6 | |
Transmembranei | 197 – 217 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 218 – 230 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 231 – 251 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 252 – 288 | PeriplasmicSequence analysisAdd BLAST | 37 | |
Transmembranei | 289 – 309 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 310 – 319 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 320 – 340 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 341 – 345 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 346 – 366 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 367 – 379 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 380 – 400 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 401 – 407 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 408 – 428 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 429 – 433 | CytoplasmicSequence analysis | 5 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000165963 | 1 – 433 | Putative purine permease YbbYAdd BLAST | 433 |
Proteomic databases
PaxDbi | P77328 |
PRIDEi | P77328 |
Expressioni
Inductioni
By glyoxylate.
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259872, 210 interactors |
IntActi | P77328, 1 interactor |
STRINGi | 511145.b0513 |
Family & Domainsi
Sequence similaritiesi
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2233, Bacteria |
HOGENOMi | CLU_017959_0_0_6 |
InParanoidi | P77328 |
PhylomeDBi | P77328 |
Family and domain databases
InterProi | View protein in InterPro IPR006043, Xant/urac/vitC |
Pfami | View protein in Pfam PF00860, Xan_ur_permease, 1 hit |
i Sequence
Sequence statusi: Complete.
P77328-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFNFAVSRES LLSGFQWFFF IFCNTVVVPP TLLSAFQLPQ SSLLTLTQYA
60 70 80 90 100
FLATALACFA QAFCGHRRAI MEGPGGLWWG TILTITLGEA SRGTPINDIA
110 120 130 140 150
TSLAVGIALS GVLTMLIGFS GLGHRLARLF TPSVMVLFML MLGAQLTTIF
160 170 180 190 200
FKGMLGLPFG IADPNFKIQL PPFALSVAVM CLVLAMIIFL PQRFARYGLL
210 220 230 240 250
VGTITGWLLW YFCFPSSHSL SGELHWQWFP LGSGGALSPG IILTAVITGL
260 270 280 290 300
VNISNTYGAI RGTDVFYPQQ GAGNTRYRRS FVATGFMTLI TVPLAVIPFS
310 320 330 340 350
PFVSSIGLLT QTGDYTRRSF IYGSVICLLV ALVPALTRLF CSIPLPVSSA
360 370 380 390 400
VMLVSYLPLL FSALVFSQQI TFTARNIYRL ALPLFVGIFL MALPPVYLQD
410 420 430
LPLTLRPLLS NGLLVGILLA VLMDNLIPWE RIE
Sequence cautioni
The sequence AAB40265 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U89279 Genomic DNA Translation: AAB93854.1 U82664 Genomic DNA Translation: AAB40265.1 Different initiation. U00096 Genomic DNA Translation: AAC73615.2 AP009048 Genomic DNA Translation: BAE76291.1 |
RefSeqi | NP_415046.4, NC_000913.3 WP_001302767.1, NZ_SSZK01000024.1 |
Genome annotation databases
EnsemblBacteriai | AAC73615; AAC73615; b0513 BAE76291; BAE76291; BAE76291 |
GeneIDi | 945131 |
KEGGi | ecj:JW0501 eco:b0513 |
PATRICi | fig|1411691.4.peg.1765 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U89279 Genomic DNA Translation: AAB93854.1 U82664 Genomic DNA Translation: AAB40265.1 Different initiation. U00096 Genomic DNA Translation: AAC73615.2 AP009048 Genomic DNA Translation: BAE76291.1 |
RefSeqi | NP_415046.4, NC_000913.3 WP_001302767.1, NZ_SSZK01000024.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4259872, 210 interactors |
IntActi | P77328, 1 interactor |
STRINGi | 511145.b0513 |
Protein family/group databases
TCDBi | 2.A.40.5.1, the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family |
Proteomic databases
PaxDbi | P77328 |
PRIDEi | P77328 |
Protocols and materials databases
DNASUi | 945131 |
Genome annotation databases
EnsemblBacteriai | AAC73615; AAC73615; b0513 BAE76291; BAE76291; BAE76291 |
GeneIDi | 945131 |
KEGGi | ecj:JW0501 eco:b0513 |
PATRICi | fig|1411691.4.peg.1765 |
Organism-specific databases
EchoBASEi | EB3385 |
Phylogenomic databases
eggNOGi | COG2233, Bacteria |
HOGENOMi | CLU_017959_0_0_6 |
InParanoidi | P77328 |
PhylomeDBi | P77328 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6282-MONOMER |
Miscellaneous databases
PROi | PR:P77328 |
Family and domain databases
InterProi | View protein in InterPro IPR006043, Xant/urac/vitC |
Pfami | View protein in Pfam PF00860, Xan_ur_permease, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YBBY_ECOLI | |
Accessioni | P77328Primary (citable) accession number: P77328 Secondary accession number(s): Q2MBR5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | December 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 134 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families