Chaperone protein HscC

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATPase activity Source: EcoCyc <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 9735342
• ATPase activity, coupled Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • 21873635
• ATP binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• heat shock protein binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• misfolded protein binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• protein binding involved in protein folding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• unfolded protein binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635

GO - Biological processⁱ

• cellular response to heat Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• cellular response to unfolded protein Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• chaperone cofactor-dependent protein refolding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• protein refolding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• response to unfolded protein Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

GO - Cellular componentⁱ

• cytoplasm Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductionⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

GO - Molecular functionⁱ

• heat shock protein binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• misfolded protein binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• protein binding involved in protein folding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635
• unfolded protein binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • 21873635

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MDNAELAIGI DLGTTNSLIA VWKDGAAQLI PNKFGEYLTP SIISMDENNH 
        60         70         80         90        100
ILVGKPAVSR RTSHPDKTAA LFKRAMGSNT NWRLGSDTFN APELSSLVLR 
       110        120        130        140        150
SLKEDAEEFL QRPIKDVVIS VPAYFSDEQR KHTRLAAELA GLNAVRLINE 
       160        170        180        190        200
PTAAAMAYGL HTQQNTRSLV FDLGGGTFDV TVLEYATPVI EVHASAGDNF 
       210        220        230        240        250
LGGEDFTHML VDEVLKRADV ARTTLNESEL AALYACVEAA KCSNQSPLHI 
       260        270        280        290        300
RWQYQEETRE CEFYENELED LWLPLLNRLR VPIEQALRDA RLKPSQIDSL 
       310        320        330        340        350
VLVGGASQMP LVQRIAVRLF GKLPYQSYDP STIVALGAAI QAACRLRSED 
       360        370        380        390        400
IEEVILTDIC PYSLGVEVNR QGVSGIFSPI IERNTTVPVS RVETYSTMHP 
       410        420        430        440        450
EQDSITVNVY QGENHKVKNN ILVESFDVPL KKTGAYQSID IRFSYDINGL 
       460        470        480        490        500
LEVDVLLEDG SVKSRVINHS PVTLSAQQIE ESRTRLSALK IYPRDMLINR 
       510        520        530        540        550
TFKAKLEELW ARALGDEREE IGRVITDFDA ALQSNDMARV DEVRRRASDY 

LAIEIP                                                 

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. SIMILARITY comments
   Index of protein domains and families
2. Escherichia coli
   Escherichia coli (strain K12): entries and cross-references to EcoGene